Search or add a thesis

Advanced Search (Beta)
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
Loading...

ہویا جثہ ڈانواں ڈول

ہویا جثہ ڈانواں ڈول
مینوں اندروں ویکھ پھرول
میرے منہ وچ تیرا ناں
کردے مینوں لوک مخول
سن کے خبر مہنگائیاں والی
دل وچ ہندا ہردم ھول
گلاں رج کے کر نہ سکے
بھانویں رہندے کول کول
کوئی بھانویں ویکھے نہ ویکھے
ڈر کے رب توں پورا تول
موت سرے تے ہر دم بندیا
اُچا بول نہ ہر گز بول
اگاں وچ نہ ساڑ گلاباں
مٹی وچ نہ موتی رول

A Comparison of Bahaullah’s Religious Unity With Akbar’s Eclectic Din-E-Elāhi

Mirza Husayn Ali Nuri (1817-1892) was one of the early followers of the Bab, and later took the title of Bahaullah’s mission was about to bring unity of all the mankind. He invited the world’s religion followers to peaceful coexistence with amity and harmony. He claimed that he was unique, in giving the idea of ‘ Most Great Peace’ through ‘Religious unity’ and a ‘Global civilization’ as a chosen ‘Manifestation of God’. He claimed to be a messenger from God referring to the fulfillment of the eschatological expectations of Islam, Christianity, and other major religions. He wrote many religious works, most notably the Kitab i Aqdas, the Kitab i Iqan and Hidden Words. In the History of Sub-continent, Great Mughal emperor Jallal ud Din Mohammad Akbar (1542-1605) is also known for the great task of ‘Religious unity’. Disillusioned with orthodox Islam and perhaps hoping to bring about religious unity within his empire, Akbar promulgated Din i Ilahi, a syncretic creed derived from Islam, Hinduism, Zoroastrianism, and Christianity. Majority of muslims condemned him to deform the real shape of true Islam. Akbar was deeply interested in religious and philosophical matters. In 1575, he built a hall called the Ibadat Khana ("House of Worship") at Fatehpur Sikri, to which he invited theologians, mystics and selected courtiers renowned for their intellectual achievements and discussed matters of spirituality with them. The policy of sulh-e-kul, which formed the essence of D┘n-e-Elāhi, was adopted by Akbar not merely for religious purposes, but as a part of general imperial administrative policy. With the passage of time D┘n-e-Elāhi lost its attraction and became a dead religion. It is interesting to make a comparison between the two.

Antimicrobial, Antioxidant and Protective Efficacy of Flower and Leaf Extracts of Calotropis Procera Against Free Radical Damage

Different soluble fractions viz., hexane, ethyl acetate, butanol and ethanol of Calotropis procera (Ait.) R. Br. were screened for their antimicrobial properties by using agar-well diffusion method against the human pathogens viz., Escherichia coli and Salmonella typhi (Gram negative), methcillin resistant Staphylococcus aureus and Micrococcus luteus (Gram positive), in vitro antioxidant properties were analyzed by means of DPPH free radical scavenging method, reducing ability assay and lipid peroxidation inhibition method. Furthermore, in vivo protective efficacy of C. procera extract against (NSAID) ibuprofen-induced nephrotoxicity in rat model was also determined by evaluating renal function markers, plasma measure of antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT) along with the determination of tissue lipid peroxidation markers, i.e. aldehyde products malonyldialdehyde (MDA) and 4- hydroxy-nonenal (4-HNE). Phytochemical analysis was also carried out for the detection of phenolic constituents, amino acids, protein, carbohydrates, reducing and non-reducing sugars in test plant. In the present findings the hexane fraction of C. procera flower and leaf have been proved very significant with maximum zones of inhibition i.e., flower (22mm) and leaf (23mm) against M. luteus. While, other tested fractions of C. procera flower and leaf showed significant antimicrobial activity against all pathogens. Whereas, in the present finding it was also determined that the flower ethanol extract showed the highest DPPH free radical scavenging activity (88.19% with 8 mg/ml) as compared to BHA which showed 85% scavenging activity as standard. Similarly, C. procera flower and leaf extracts were also analyzed for reducing capacity. The highest absorbance (i.e., 1.827 with 10mg/ml) was recorded in C. procera flower water extract as compared to standard which showed (0.238) absorbance. In vitro lipid peroxidation inhibition, another model was used to check the antioxidant capacity of C. procera. Flower water extract exhibited a concentration dependent increase in lipid peroxidation inhibition, the highest value is (89.58% with 10mg/ml) while the lipid peroxidation value in C. procera leaf water extract (i.e., 75.11% with 10mg/ml) and leaf ethyl acetate extract showed (75.11% with 8mg/ml). While, BHA (85%) and ascorbic acid (75.5%) showed lower values as compared to tested plant. However, body weight loss was successfully restored by the coadministration of Ibuprofen with C. procera hexane extract. While, increased level of renal function markers (urea, creatinine) was normalized by the administration of C. procera hexane with ibuprofen treatment. The imbalance in oxidative status was determined by evaluating decreased level of catalase, superoxide dismutase and glutathione along with increased levels of malonyldialdehyde and 4- hydroxynonenal, which was counteracted by the co-administration of C. procera hexane extract with ibuprofen which maintained cell sustainability and indicated nephro-protective activity of C. procera. Besides the above results C. procera leaf and flower aqueous extract were also used to check enzymatic activities of glucoamylase, α-amylase and urease enzymes. The flower extract is found proved to be a good enhancer of glucoamylase, α-amylase and urease activity as compared to leaf extract. A number of phytoconstituents were also detected. The presence of phytochemicals in C. procera may indicate a good correlation with that of antibacterial, antioxidant potential and protective role for in vivo model which also proved as a good enhancer of enzyme activities. Thus due to aforementioned activities, Calotropis procera may serve as a better and a protective therapeutic agent than any other synthetic drug.
Author