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مولاناعبدالماجد بدایونی

مولانا عبدالماجد بدایونی
افسوس ہے کہ اس سال کا خاتمہ بھی ماتم پر ہوتا ہے، خطیب الامت مولانا عبدالماجد بدایونی رحمۃ اﷲ علیہ کا ناگہانی سانحۂ ارتحال ہمارے لئے ذاتی اور قومی دونوں حیثیتوں سے وہ غم ہے جو بھلائے نہیں بھولتا۔
۱۴؍ دسمبر ۱۹۳۱؁ء کی نصف شب کو یہ واقعہ لکھنؤ صدر میں پیش آیا تو میں وہاں اس صبح کو موجود تھا، ۸ بجے صبح کو خبر ہوئی جب ۹ بجے کے بعد وہاں پہنچا تو مرحوم کی زندہ روح خدا کے پاس اور مردہ لاش بدایوں کو منتقل ہوچکی تھی۔
مولانا عبدالماجد بدایونی کون تھے؟ لکھنے والے ان کے محامد و اوصاف صفحوں میں لکھیں گے اور بیان کرنے والے گھنٹوں بیان کریں گے، لیکن اس سارے دفتر کو صرف ایک لفظ میں اگر ادا کرنا چاہیں تو کہہ سکتے کہ وہ ہستی جو سرتاپا محبت تھی، خدا سے محبت رسول سے محبت، آل رسول سے محبت، اکابر سے محبت، دوستوں سے محبت، کارکنوں سے محبت، عزیزوں سے محبت۔
حضرات علماء کے طبقہ میں ان کی ذات ہر حیثیت سے قابل فخر تھی، ان تمام لوگوں پر جنھوں نے طرابلس کے زمانہ سے اسلامی جدوجہد میں شرکت کی، ان بیس برسوں میں مختلف دور گزرے، یعنی کچھ آرام و سکون، پھر کچھ سعی و محنت، کچھ عزلت گزینی اور پھر ہنگامہ آرائی، کچھ توقف، پھر تیزرفتاری، اس طرح ان کی زندگی کے ایام وقتاًفوقتاً گزرتے رہے، مگر جماعت علماء میں یہی ایک ہستی تھی جس کی زندگی کے ایک لمحہ کو بھی اس وقت سے چین نصیب نہ ہوا، ہر وقت و ہر نفس ان کو کام کی ایک دھن لگی ہوئی تھی، جس کے پیچھے ان کا آرام چین خانگی سکون، اہل و عیال اور جان و مال ہر چیز قربان تھی، یہ بھی سماں گزرا ہے کہ ان کے گھر میں کفن دفن کا...

صلح حدیبیہ: آنحضرت کی ﷺ سیاسی، معاشرتی اور دفاعی حکمت عملی

Hazrat Muhammad (SAW) is the last Apostle to human beings. He was gifted with a divine Deen having complete code of life. Every field of life has been discussed in the Holy Quran and Sunnah of the Prophet r. As an Apostle, head of the state and army commander, He guided the mankind and provided an excellent example in all the perspectives of life. As a commander of the Islamic forces, the Holy Prophet r fought twenty seven Ghazwat after migration to Madina. In Zeqaida 6 AH, during the pact of Hudaibia a complete turn was taken by Muslims. After this event, the Muslim army role changed to offensive rather than defensive. Immediately, after the pact, the Holy Prophet r attacked on Khyber in Muharram 7th AH, while the whole Hijaz region was captured during the Ghazwa Fath-i-Makkah. In this article, the strategy and tactics employed by the Holy Prophet r during Hudaibia truce have been discussed. These tactics are useful and beneficial in modern era warfare also. As an ideal for all the Ummah, lessons should be extracted by the commanders to defend their motherland and ideological boundries.

Synthesis and Applications of Piperazine, Bis-Indole Derivatives and Gold Nanoparticles of Thiolated Ligands

This dissertation has been divided into four chapters and each chapter has its own numbering of compounds and references. General introduction related to the importance of heterocycle based drugs, drug designing and value of lead molecules in drug designing. This research work describes synthesis and bioactivities of different class of heterocycles such as piperazine, bisindole analogs in search of important therapeutic agents and also includes functionalized gold nanoparticles for catalytic study. During this research study, a variety of piperazine, and bisindole analogs were synthesized and screened for enzyme inhibition studies (thymidine phosphorylase, urease, antioxidant, β-glucuronidase and α-glucosidase, anti-Leishmania). Functionalized gold nanoparticles were synthesized for modulating their catalytic ability. The results obtained from this study are encouraging which are discussed separately in the forthcoming chapters 1, 2, 3 and 4. In first chapter, piperazine analogues are studied. We have synthesized eighteen piperazine derivatives (1-18) and evaluated for thymidine phosphorylase, urease, antioxidant, b-glucuronidase and α-glucosidase activity. All analogues showed potent thymidine phosphorylase inhibitory potential with IC50 values ranging between 0.2 ± 0.01 to 42.20 ± 0.70 μM when compared with standard 7-Deazaxanthine (IC50 value of 38.68 ± 1.12 μM). Compound 17 was found to be the most active among the series while compound 18 was found to be the least active. All these analogues showed varying degree of urease, antioxidant, b-glucuronidase and α-glucosidase activity. xi In second chapter, bis-indole analogues are studied. We have synthesized twenty seven bis-indole analogues (1-27) and evaluate their anti-leishmanial, urease, antioxidant, and b-glucuronidase activity. All compounds showed outstanding anti-leishmanial inhibitory potential with IC50 values ranging from 0.7 ± 0.01 to 13.30 ± 0.50 μM respectively when compared with standard pentamidine with IC50 value of 7.20 ± 0.20 μM. All analogues showed greater potential than standard except 23 when compared with standard. All these compounds showed varying degree of urease, antioxidant, b-glucuronidase and α-glucosidase activity. In third chapter, functionalized gold nanoparticles are studied. We report the fabrication of a family of nanozymes comprised of bioorthogonal ruthenium catalysts inserted in the protective monolayer of gold nanoparticles. By introducing simple modifications to the functional groups at the surface of the nanozymes, we have demonstrated control over the kinetic mechanism of our system. Cationic nanozymes with hydrophobic surface functionalities tend to replicate the classical Michaelis Menten model, while those with polar groups display substrate inhibition behaviour, a key mechanism present in 20% of natural enzymes. The structural parameters described herein can be used for creating artificial nano-systems that mimic the complexity observed in cell machinery. In fourth chapter we discussed the different bioassay protocols in detail.
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