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Formal Modeling and Analysis of Insulin Resistance Pathway

Thesis Info

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Author

Alamdar Hussain

Department

Department of Bioinformatics/Biosciences

Program

MS

Institute

Capital University of Science & Technology

Institute Type

Private

City

Islamabad

Country

Pakistan

Thesis Completing Year

2019

Subject

Bioinformatics/Biosciences

Language

English

Link

https://thesis.cust.edu.pk/UploadedFiles/MBI173005.pdf

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676709389077

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ان کو خبر نہیں کہ لہو بولتا بھی ہے

ان کو خبرنہیں کہ لہو بولتا بھی ہے
نحمدہ ونصلی علی رسولہ الکریم امّا بعد فاعوذ بااللہ من الشیطن الرجیم
بسم اللہ الرحمن الرحیم
معزز اسا تذہ کرام اور میرے ہم مکتب شاہینو!
آج مجھے جس موضوع پر گفتگو کرنی ہے وہ ہے:’’ان کو خبرنہیں کہ لہو بولتا بھی ہے ‘‘
جنابِ صدر!
ہر اک کا انداز گفتگو مختلف ہے، فلک کی فضاء میں طیور بولتے ہیں، جنگل و بیاباں میں درندے بولتے ہیں، گھر میں کو چہ گرد مرغ بولتے ہیں، رات کی تنہائیوں میں مختلف جانور آوازیں نکالتے ہیں، فصیح زبان میں حیوان ناطق بولتے ہیں، انسانوں کے گروہ کانمائندہ انسان زبان کھول کر بولتا ہے۔
معزز سامعین!
جو عظمت کی داستاں رقم کر جاتے ہیں، جو اپنی جان کا نذرانہ پیش کر کے تاریخ کے اوراق کی زینت بن جاتے ہیں، جو زندگی کی بازی ہار کر بھی دامنِ حیات سے وابستہ رہتے ہیں وہ لوگ زندگی میں نہیں بعد از وفات بھی فلک جرأت و شجاعت پر آفتاب بن کر چمکتے ہیں۔ ان کی رگوں میں دوڑنے والا خون بھی حرارت و تمازت لیے ہوتا ہے اور شہادت کی منزل پر فائز ہونے کے باوجود بھی ان کا لہو بولتا ہے۔ جیسے آج کل کشمیر کے مجاہدین دشمن کے خلاف صف آرا ہیں۔
جنابِ صدر!
زندگی کے پر لطف لمحات گزارنے کے بعد جب وہ شہادت کے مقام پر رفیعہ کے حصول میں کامیاب ہوتے ہیں تو ان کے جسم سے بہنے والا خون بھی پس ماندگان کے لیے مہمیز ثابت ہوتا ہے اور یہی اس کی آواز ہے کہ انسانیت کے دامن سے مر بوط لوگ ایک ایسے جذبے سے حصول منزل کے لیے مستعد ہو جاتے ہیں۔
جنابِ صدر!
قوموں کی زندگی میں کچھ ایسے لمحات بھی آتے ہیں۔ جب انہیں تاریخ کے نازک ترین...

Art and Architecture as A Space for Kalash Identity (A Case Study of Bumburet Valley in District Chitral Pakistan)

The present study was conducted in Bumburet valley of Kalash, District Chitral, Pakistan. The key technique used for data collection was participant observation in which the researcher lived in the community, observed and documented their cultural patterns as an indicator of their traditional culture which includes religious songs, folklore, dress, art and crafts, as a basis for identity. The basic purpose of the study was to understand the role and significance of arts and architecture as a prime tool for establishing identity for the conventional people of Kalash. The people of Kalash have managed to maintain their identity through their unique arts and crafts. Tradition resists change and most often remains unaltered in a static spatial arrangement. The changes which incorporate in Kalash traditions may find their way through peripheral adjustments. The traditions in art and crafts are scanty to find and the present artifacts does not throw any light on their origin. The art and architecture available signify their unique ways, and tradition which is definitely different from the other ethnic tribes in the shared geographical arrangement. The Kalash ethnic identity has faced several challenges like colonization in the past and modernization and technological advancement and conversion to Islam in the present. The Kalash insist on keeping their self-identity as well as participating in modernity. They have maintained their centuries old traditional culture, despite the fact of current globalization, and modernization.

Iron Availability in Calcareous Soils

Iron (Fe) is a widely deficient micronutrient in agriculture particularly on alkaline and calcareous soils due to formation of insoluble compounds in soil as well its inactivation in plant body. Several soil-related characteristics may lead to development of Fe chlorosis. Prediction of development of Fe chlorosis on basis of single soil parameter is not easy for perennial crops. To cure Fe deficiencies, right choice of rootstock and efficient Fe sources for soil application need to be explored. The present project was designed to study the different soil Fe forms, soil properties and their relation with citrus leaf Fe. For soil solution Fe studies, Buchner Funnel Technique (BFT) was used to determine water soluble Fe in different soils and Fe buffer power of different soils. Different Fe sources were tested in their ability to provide soluble Fe over period of time. Responses of different citrus rootstock seedling were evaluated in calcareous medium. DTPA-extractable Fe and water soluble Fe though represents the available Fe in soils were found unable to justify the symptoms of Fe chlorosis on citrus leaves in our study. Ferrihydrite Fe oxide is the main source of soil Fe in calcareous soils and controls plant available Fe at each depth. Soil pH was found in inverse relation to leaf active Fe. Water soluble Fe extracted from different soils using BFT revealed that all soils were above the critical level of 1 μM Fe required for mass flow. While comparing different Fe sources, we found organic amendments better than inorganic amendments in their ability to supply Fe over long period of time. Inorganic Fe sources rapidly became insoluble regardless of soil type. Vivianite was found slightly resistant to oxidation as compared to FeSO 4 . Among chelates EDDHA is highly stable as compared to DTPA. Citrus rootstock seedlings responded differently with application of Fe with and without CaCO 3 in growth medium. Rootstocks differed in their ability to take up Fe from CaCO 3 medium and to efficiently utilize Fe. Rough lemon found to be efficient rootstock to cope Fe nutrition disorders