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Preparation and characterization of polyvinyl alcohol-gelatin hydrogel membranes for biomedical application

Thesis Info

Author

Naila Imtiaz

Supervisor

Bushra Uzair; Bilal Khan Niazi

Department

Department of Bioinformatics and Biotechnology

Program

MS

Institute

International Islamic University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2016

Thesis Completion Status

Completed

Page

105

Subject

Bioinformatics & Biotechnology

Language

English

Other

MS 668.405 NAP

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676721465669

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شمس العلماء عبدالرحمن شاطرؔ

شمس العلماء عبدالرحمان شاطرؔ مرحوم
دکن ٹائمز مدراس میں یہ پڑھ کر بہت افسوس ہوا کہ مدراس کے مشہور و ممتاز فلسفی شاعر مولانا شاطرؔ کا وسط اپریل ۱۹۴۳؁ء میں انتقال ہوگیا۔
ارکاٹ احاطۂ مدراس میں اسلامی علم و تمدن کی فراموش شدہ تاریخ کا ایک ورق ہے، نواب ارکاٹ کا محل ارکاٹ کے جنگی خاتمہ کے بعد خود شہر مدراس ہے، شمس العلماء عبدالرحمان شاطر اسی برج فلکی کے آفتاب تھے، عمر ستر کے قریب ہوگی، اردو، عربی، فارسی اور انگریزی زبانوں سے واقف تھے، نواب صاحب ارکاٹ کے سکریٹری بھی تھے اور مدراس ہائیکورٹ میں مترجم بھی رہے تھے، گو وطن مدراس تھا، مگر ۱۹۰۱؁ء اور ۱۹۰۳؁ء میں حیدرآباد دکن کے بزم علمی میں اس کے شریک تھے، جب مولانا شررؔ اور داغؔ اور گرامیؔ حیدرآباد کی زینت تھے، وہ ان کی مجلسوں میں شریک ہوتے تھے اور ان سے اپنے ذوقِ ادب کی پرورش کرتے تھے اور اسی زمانہ سے وہ مولانا کے قریب رہنے والوں اور قریب سے جاننے والوں میں تھے اور ان کی وہی محبت تھی جو حضرت الاستاذ کی وراثت میں مجھے ملی تھی۔
عبدالرحمان مرحوم شاعر تھے، شاطرؔ تخلص کرتے تھے، اشعار حکیمانہ اور فلسفیانہ کہتے تھے، قطعات، رباعیات اور قصائد موزوں کرتے تھے، جدید سائنس اور فلسفہ کے مسائل کو اسلامی الٓہیات سے تطبیق دیتے تھے، زبان سخت تھی اور مشکل الفاظ کے استعمال سے ان کو پرہیز نہ تھا، ان کی سب سے مشہور فلسفیانہ نظم ’’اعجازِ عشق‘‘ ہے، جو ایک طویل رائیہ قصیدہ ہے جس میں جدید و قدیم فلسفیانہ مسائل و آراء سے الہیات اسلامیہ کی تفسیر و تشریح کی ہے یہ نظم ۱۹۰۴؁ء میں لکھی گئی تھی اور اس زمانہ کے تمام اکابر و مشاہیر مولانا حالی،مولاناشبلی، مولانا نذیر احمد، مولوی ذکاء اﷲ خاں، نواب عمادالملک، مولوی سیداکبر حسین، پروفیسر عبدالغفور شہباز، امجد...

Awareness about Workplace Harassment among Female Nursing Students and Nursing Staff of a Teaching Hospital in Lahore

Background: Harassment of working women is a common social and human rights problem and healthcare settings are no exception. This unacceptable situation has many avoidable determinants that need preventive measures to ensure, safe and secure working environment for nurses. Objectives: To assess the knowledge and understanding among female nursing students and nursing staff about workplace harassment in a tertiary healthcare facility. Methods: It was a cross-sectional study conducted at Tertiary care hospital Lahore from July to September 2018. Convenient sampling technique was used to collect data. Verbal informed consent of voluntary participants was taken. Anonymity and confidentiality was assured. SPSS version 21 was used for data analysis. The participants (n=80) comprised of senior female nurses students (62.5%) and senior nursing staff (37.5%), aged 18 to 46 years. Results: Awareness about common harassment forms was adequate (81.3%). Adverse effects included mental health problems (83.8%) and low self-esteem (72.5%). A large percentage of nurses (62.5%) intended to report such personal incident to institutional head and 72.5% were willing to accompany victims for such reporting. 77.5% desired arranging informative sessions and holding counseling for victims (78.8%) at workplace. Only 22.5% had vague idea about official protective legal frameworks. Conclusions: Workplace harassment of female workers is quite prevalent but under-reported phenomena in Pakistan. All organizations and institutions must have a harassment policy to protect the females.  

Biogenic Synthesis, Characterization and Pharmacological Evaluation of Nano-Particles Prepared by Using the Extracts of Arisaema Jacquemontii, Hedera Nepalensis and Valeriana Jatamansi

Nanobiotechnology and green synthesis of nanoparticles (NPs) are novel and efficient alternatives for synthesis of metal NPs using extracts of medicinal plants. Arisaema jacquemontii (family: Araceae), Hedera nepalensis (family: Araliaceae) and Valariana jatamansi (family: Valerianaceae) are important medicinal plants of Himalayas and Kashmir. A. jacquemontii has anti-proliferative property and is traditionally used as snakebite antidote, ringworm killer and to treat skin diseases. Leaf juice of H. nepalensis is given in dyspepsia and leaves paste is applied on ulcers. V. jatamansi is used as tranquilliser, carminative, anti-inflammatory, expectorant and muscle relaxant. The aim of the present study was to investigate the green synthesis and characterization of nanoparticles (NPs) and pharmacological evaluation of the three plants. Methanolic extract solution (50mg/100ml de-ionized water) of selected parts of the test plants was used to synthesize gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs). Methanolic extract was mixed with gold chloride (AuCl3) solution (0.1 mM concentration) in 3:1 ratios to produce AuNPs from A. jacquemontii tuber and 4:1 ratios for AuNPs from the rest of the samples. To synthesize AgNPs from tubers, 0.1mM AgNO3 was mixed with extract at 1:5 ratios. AgNPs were formed from H. nepalensis stem and leaves at 1:5 and 1:2 ratios respectively. AgNPs of V. jatamansi root and shoot were synthesized at 1:10 and 1:5 ratios respectively. Preliminary observation of synthesis of NPs was carried out by visual detection of color change from light yellow to dark purple and dark yellow/brown for AuNPs and AgNPs synthesis respectively. UV-vis spectrophotometric analysis further confirmed the synthesis of AgNPs and AuNPs by showing SPR peak in 400-500nm and 500-600nm range respectively. Temperature and salt stability studies of AgNPs and AuNPs revealed the stability of NPs at 20-40°C temperature and at milimolar salt concentration. FTIR confirmed the involvement of mainly carboxylic acid/phenol, tertiary alcohol, alkene, alkane and alcohol of plant extracts in reduction of Au-metal to form AuNPs. XRD analysis revealed that all AuNPs were crystalline in nature and the average nanocrystallite size for AuNPs synthesized from all three test plants was in the range of 6.23nm-10.92nm. Crystals were cubic in nature. SEM analysis revealed average size of 36nm, 32nm, 29nm, 25nm and 24nm for tubers, stem, leaves, root and shoot nanosphere AuNPs. According to XRD data, synthesized AgNPs were mainly crystalline in nature. SEM results reported size of synthesized AgNPs in 30nm-49nm range. AgNPs of all the samples were spherical in shape. FTIR analysis revealed the involvement of mainly alkenes, carboxylic acids, ether and aromatic ring (aryl) groups in reduction of Ag-metal. Overall among all the tested microbes, P. aeruginosa was the most sensitive microbe (62-88% growth inhibition) followed by C. albicans (59-82% growth inhibition). The most resistant bacterium was K. pneumonia (35-47% growth inhibition). V. jatamansi showed better antimicrobial activities than the other two tested plant species. AgNPs reported greater antimicrobial activity than AuNPs. Among all the tested extracts, generally, n-butanol fractions and methanolic crude extracts showed higher antioxidant activity. NPs also reported their antioxidant potential. Phytochemical screening of extracts indicated the presence of several bioactive compounds in the extract including flavonoids, sterols, saponins, tannins, alkaloids and oils in different extracts of different parts of all the three test plant species. On the basis of these results it is evident that all the three plants can be used for stable and active NPs synthesis that posses antimicrobial and antioxidant properties. Extracts of test plants also revealed antifungal, antibacterial and antioxidant properties due to the presence of bioactive compounds in it.