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Mutational analysis of CEACAMI gene involved in Insulin resistance in Pakistani population

Thesis Info

Author

Shah, Syeda Saba

Supervisor

Asma Gul; Muhammad Ismail

Department

Department of Bioinformatics and Biotechnology

Program

MS

Institute

International Islamic University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2016

Thesis Completion Status

Completed

Page

49

Subject

Bioinformatics & Biotechnology

Language

English

Other

MS 576.5 SHM

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676721988220

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پہلی بات

    سیالکوٹ ایک تاریخی اور ادبی خطہ رہا ہے۔ اس کی تاریخ پانچ ہزار سال پر محیط ہے۔ سیالکوٹ تاریخی ، جغرافیائی ، ثقافتی،سماجی،تہذیبی،علمی اور ادبی لہاظ سے دوسرے عالمی ادبی شہروں سے کم نہیں۔سیالکوٹ کو اقبال و فیض کے مولد ہونے کا بھی لازوال فخر حاصل ہے۔ بقول گوپی چند نارنگ :
    ’’ بیسویں صدی کے اردو ادب کو سیالکوٹ کھا گیا نصف اوّل اقبال اور نصف دوم فیض‘‘۔
    سیالکوٹ کی مٹی بڑی زرخیز اور مردم خیز ہے ۔ سر زمینِ سیالکوٹ نے علم و ادب اور فنونِ لطیفہ کے میدانوں میں گراں قدر خدمات سر انجام دی ہیں۔ داغ دہلوی اور اقبال کے کئی شاگرد سیالکوٹ کے رہنے والے تھے۔ اقبال و فیض کے علاوہ ارض اقبال میں متعدد مشاہیر پیدا ہوئے جن کے شعری و نثری سرمائے میں آ فاقی موضوعات ، اصناف اور اسالیب موجود ہیں۔ اس طرح خطہء سیالکوٹ کا تخلیقی ادب عالمی ادب کے ہم پلہ ہے۔ راقم الحروف نے اپنی تخلیق بعنوان’’ ارضِ اقبال ۔ آ فاقیت کے آ ئینے میں‘‘ سیالکوٹ سے منسلک مختلف شعرا و ادبا کی ادبی خدمات کا تحقیقی و تنقیدی جائزہ لیا ہے۔ یہ تحقیقی وتنقیدی جائزہ ادبی خدمات کے علاوہ ادبی رجحانات، ادبی اصناف، اسالیب اور اقبال شناسی کے حوالے سے بھی ہے۔
     یہ تصنیف پندرہ مقالات پر مشتمل ہے ۔ جس میں حوالہ جات ، حواشی اور تعلیقات کا خاص خیال رکھا گیا ہے۔ یہ مقالات ہائر ایجوکیشن کمیشن اسلام آباد ،پاکستان کے منظور شدہ ریسرچ جرنلز میں شائع ہو چکے ہیں۔
 ڈاکٹر نصیر احمد اسد
سیالکوٹ، پنجاب، پاکستان

موقف محمود سامي البارودي ومحمد إقبال من السياسة: دراسة تحليلية وموازنة

It is obvious to everyone who has associated with Arabic and Urdu literature that both Mahmood Sami al Baroodi and Allma Muhammad Iqbal are the shining stars in the orbit of Arabic and Urdu literature, because each of them made the world busy by his literature, and tied to blow the spirit of innovation in the style of poetry and made free it from affectation and returned it to sincerity and integrity of expression, and each of them  developed his political and cultural thought by traveling to Europe. In this article we have tried to highlight the political and literary life of Iqbal and al Barood, we also tried to analyze their efforts in the field of literature and their stand on the politics

Influence of Salt Stress on Some Physiological and Biochemical Attributes and Oil Composition of a Potential Oilseed Crop Safflower Carthamus Tinctorius L. .

The principal objectives of the present investigation were to assess inter- cultivar variation for salt tolerance in safflower, draw relationships of various physiological and biochemical attributes to salt tolerance of safflower, identify selection criteria for further improvement in salt tolerance of safflower through specific breeding programs and to appraise whether or not salt stress alters the composition and quality of safflower oil. Different experiments were carried out to assess variation in salt tolerance in 10 accessions (Safflower-31, Safflower-32, Safflower-33, Safflower-34, Safflower-35, Safflower-36, Safflower-37, Safflower-38, Safflower-39, Safflower-78) of safflower (Carthamus tinctorius L.) at varying levels of salt (NaCl) at different growth stages, germination, seedling and adult stages. The results of the germination experiment showed that salt stress had an inhibitory effect on germination percentage and seedling biomass of all 10 accessions. A significant variation in the accessions was observed at the two higher salt levels (180 and 240 mM). While ranking the accessions on the basis of their potential for germination and producing seedling biomass at 240 mM NaCl, lines Safflower- 31 and Safflower-35 were found to be tolerant, Safflower-33, Safflower-37, Safflower-38 and Safflower-78 salt sensitive, and Safflower-32, Safflower- 34, Safflower-36 and Safflower-39 moderately tolerant. To further evaluate safflower lines for their performance at later growth stages, an experiment was conducted using two salt levels (0 control, 150 mM NaCl). Salt stress caused a marked reduction in biomass production, photosynthetic pigments, leaf water relations, gas exchange characteristics, proline content, mineral nutrients, activities of some key antioxidant enzymes, different fatty acids, tocopherol contents and yield attributes. A significant inter-cultivar variation was found in the set of 10 diverse safflower accessions at the adult stage. Although variation for salt tolerance was found at all growth stages, that found at the germination and seedling stage was not maintained at the vegetative or adult growth stages. On the basis of shoot biomass production at the vegetative stage, accession Safflower-37 was ranked as tolerant, while Safflower-31, Safflower-32, Safflower-34, Safflower-39, and Safflower-78 as salt sensitive. In contrast, in terms of seed yield, accessions Safflower- 32, Safflower-34, and Safflower-39 were ranked as tolerant, while Safflower-31, Safflower-33, Safflower-35, Safflower-36, and Safflower-38 as salt sensitive. A positiveassociation of net photosynthetic rate (A) with growth and seed yield was observed in the 10 diverse safflower lines under saline conditions, and thus it could be used as an effective selection criterion for salinity 2 tolerance in safflower.