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Home > التنبہ علی مشکات الھدیۃ کا ترجمہ اور تحقیقی و تجزیاتی مطالعہ: ایم فل علوم اسلامیہ

التنبہ علی مشکات الھدیۃ کا ترجمہ اور تحقیقی و تجزیاتی مطالعہ: ایم فل علوم اسلامیہ

Thesis Info

Author

مفتاح الدین

Supervisor

ہدایت اللہ خان

Department

Department of Islamic Studies

Program

Mphil

Institute

Allama Iqbal Open University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2018

Thesis Completion Status

Completed

Page

207ص

Subject

Islamic Studies

Language

Urdu

Other

Classification: 340.59 م ف ت

Added

2022-07-09 15:11:20

Modified

2023-02-19 12:33:56

ARI ID

1676729886795

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دشتِ افسوس میں اک پھول کھلا ہو جیسے

دشتِ افسوس میں اک پھول کھلا ہو جیسے
تو خزاں زاد شجر سے ہی ملا ہو جیسے

ایک مدت سے بیابانی تھی دل میں میرے
تو مرے غم مرے ہر دکھ کا صلہ ہو جیسے

روح مجروح تھی اور ادھڑے تھے ٹانکے دل کے
تیرے آنے سے ہر اک زخم سلا ہو جیسے

تم سے بچھڑیں تو کسی طور بھی ہم جی نہ سکیں
سانس تو سانس ہے تم دل کی جلا ہو جیسے

تم فضاؔ چھائی ہو اک ابرِ کرم کی صورت
ہم نہ مل پائے یہی خود سے گلہ ہو جیسے

برصغیر میں اصول تفسیر کے مناہج و دبستان اور نمائندہ شخصیات کی علمی تراث کا تجزیاتی مطالعہ

The Quranic sciences of interpretations and principles of interpretations were originated in the epoch of holy prophet (saw) but compilation of both were started later. This is called principles of interpretations, which is the basic and important part of Islamic studies. Islamic scholars, commentators and explicators explained the holy Quran in the light of principles of interpretations. These are such basic principles those are guide lines for them so they will not deviate or drop the right way while interpreting and explaining the holy verses. These principles are laid down and followed by them so that they may find the will of Allah and actual meaning of holy Quran. A little difference in principles causes a huge difference in interpretation. Different methodology in principles resulted in many schools of thought. This article focusses on examining these schools of thought found in sub-continent and introduce their main books. This article deals with chronological evolution of said knowledge i.e. Principles of interpretations, and Quranic sciences specially originated by the famous principalities and interpreters of sub-continent.

Possible Role of Neuropeptide Y Npy on Hormones During Different Phases of Menstrual Cycle in Adult Rhesus Monkey

Neuropeptide Y (NPY) acts at the hypothalamus to regulate the reproductive function by stimulating the release of GnRH from hypothalamus. In the present study a group of 5 female adult rhesus monkeys (Macaca mulatta), 5.5-9 years old, mean body weight of 10.31±0.90 kg and with menstrual cycle of 31 days was used. Changes in their body weight, behavior and sex skin color were observed throughout the cycle. Menstrual cycle of each monkey was monitored daily by recording the onset and duration of menstrual bleeding with vaginal swabs. Baseline profile of estradiol (E2), progesterone (P), prolactin (PRL) and growth hormone (GH) were measured by collecting blood sample (2 ml) on different days throughout the menstrual cycle of 31 days. Sequential blood samples (2 ml) were collected at an interval of 15 minutes for one hour before NPY administration for the hormonal baseline and for 2 hours and 15 minutes after NPY administration. In order to study the effect of NPY on plasma E2, P, PRL and GH levels on day 1 (menstrual phase), day 7 (follicular phase), day 15 (peri-ovulatory phase) and day 21 (luteal phase) of menstrual cycle, 200 μg of NPY in single bolus intravenous injection was given. Individual and mean body weight during the menstrual cycle was not significantly different. After NPY administration monkeys were relaxed and comfortable. Sex skin coloration changed progressively from whitish pink to deep red following menstrual to periovulatory phase and then decrease in colour intensity occurred during luteal phase. Baseline profile of estradiol showed that plasma E2 concentration was significantly high (P<0.001) in the periovulatory phase of menstrual cycle compared to menstrual, follicular and luteal phases. The luteal phase plasma E2 level was significantly low compared to follicular phase (P<0.003) but not significantly different from the menstrual phase. Plasma estradiol level 15 minutes after NPY administration increased non-significantly in all the four phases of menstrual cycle compared to baseline at 0 minute. Then, subsequent significant temporal increase till 45 minutes on day 1, 75 minutes on day 15, 60 minutes on day 7 and day 21 followed by subsequent significant temporal decrease. At the end of experiment plasma estradiol attained the basal level in all the four phases. Baseline profile of plasma progesterone showed significantly low levels during menstrual, follicular and periovulatory phases compared to the luteal phase. No significant difference was observed in the plasma P concentration between menstrual, follicular, and ovulatory phases. In all the four phases of menstrual cycle plasma progesterone level 15 minutes after NPY administration increased non-significantly followed by significant temporal increase till 60 minutes on day 1, 105 minutes on day 7, 135 minutes (i.e. till the end of experiment) on day 15 and 30 minutes on day 21. After then non-significant temporal decrease on day 7 and significant on day 1 (P<0.0002) and day 21 (P<0.0007) was observed. The baseline profile of plasma PRL showed that plasma PRL levels were significantly high during menstrual (P<0.013) and periovulatory phases (P<0.023) compared to luteal phase. Plasma prolactin level of follicular phase was non-significantly lower than menstrual and peri-ovulatory phases. The plasma prolactin levels of follicular and luteal phases were not different. In plasma prolactin concentration after 15 minutes of NPY bolus injection a non-significant rise was observed on day 1 followed by non-significant temporal increase till 30 minutes and then significant temporal decrease till the end of experiment. On day 7 non-significant and on day 15 significant increase in plasma prolactin level was observed 15 minutes after NPY administration followed by significant temporal decrease on day 7 (P<0.0005) and day 15 (P<0.009). On day 21 a non-significant decrease in plasma prolactin level after 15 minutes of NPY administration followed by significant temporal decreased till the end of experiment. Regression analysis of variance showed highly significant temporal decrease (P<0.0003). The base line plasma in all the four phases of menstrual cycle GH levels in all the four phases of menstrual cycle were non-significantly different (P>0.05). NPY administration inhibited the plasma GH level in all the four phases of menstrual cycle. On day 1 (menstrual phase) of menstrual cycle plasma growth hormone level 15 minutes after NPY administration decreased non-significantly with subsequent non-significant temporal decrease till 45 minutes followed by significant temporal increase till the end of experiment. A highly significant decrease in plasma GH level was observed on day 7 (follicular phase) and non-significantly on day 15 (periovulatory phase) and day 21 (luteal phase) of menstrual cycle 15 minutes after NPY administration followed by non- significant temporal decrease on day 7 and day 15, but significant temporal decrease on day 21 (P<0.004) till the end of experiment. These results show that NPY has stimulatory and inhibitory effects on the ovarian and pituitary hormones by acting as a modulator, neurotransmitter and neurohormone. NPY has applications in pharmacological fields and can be used for further research.