بادِ صبا کا وعدہ کر کے اپنے ہاتھ میں
اُس نے ہمیں تھما د ی ہے طوفاں سی زندگی
A collection of Aḥādīth of Prophet Muḥammad (May peace and blessing be upon him) compiled by Imām Bukhārī. The Muslim scholars of past and present time gave great importance to this book by making their efforts to extract the treasures hidden in this book and to present the different approaches and benefits of this book. “Al Kawākib al-Durārī” by Imām Al kirmānī is an old explanation of Ṣaḥīḥ Bukhārī. He was among those scholars who were expert in many fields at a time like knowledge about ╓adīth, its narrators, Commentary, Qirā’t, Qur‘ānic Sciences, Islamic Jurisprudence, Arabic language, Faith, Medicine, History, Geography, Astronomy etc. ╓afiz Ibn ╓ajar who also had the specialization in science of hadith and knowledge about biographies of narrators. During studying “Fatḥ al Bārī” I found that ╓afiz Ibn ╓ajar criticized on the commentary of Al kirmānī at many times in relating different sayings and signals. In this article I studied these comments of ╓afiz Ibn ╓ajar on Imam Alkirmani a critical comparison. After research I have found that ╓afiz Ibn ╓ajar has consulted “Al Kawākib al- Durārī” and quoted Imām Al kirmānī’s commentary and added it. This article approves that judgments of ╓afiz Ibn ╓ajar on conversion and transformation of text and on distorted, additional and incomplete words in the text are more authentic than Imām Al kirmānī.
The advancement in microscopic imaging techniques results in the generation of a large amount of high quality data in no time. The accurate, real time and autonomous analysis of this data is crucial for the theoretical biomedical research and clinical diagnosis. A lot of vigorous attempts are dedicated for the evolution of computer aided techniques, which improve human diagnosis by increasing efficiency, decreasing variability in the observations and reducing the human effort on labelling and classifying images. Among such determined attempts, histology image classification is one of the most significant fields due to its extensive application in pathological diagnosis such as tumor/cancer diagnosis. Inherent heterogeneous nature and random spatial intensity differences of histopathology images make the histology tissue classification a complex task. In this thesis four novel, robust and adaptive frameworks are proposed for automated and correct classification of histopathology images. The goal of this research is to achieve the expert pathologists’s diagnosis by catering inherent complexity and prevailing the variations in the opinion of different pathologists. The key contributions of this reseach are: First, a histopathological classification problem is explored from all the perspectives by performing pattern analysis at image level and cell level individually and collectively. The first proposed framework is an abstract feature based framework which performs image-level analysis to capture global texture information. The second framework performs cell-level analysis to get nuclei structure and texture. The third and fourth frameworks perform cell-level and image-level analysis to get nuclei structure and image global texture. Second, the exploration of RGB colour space is preferred to mimic the pathologists’ diagnosis process. The imperative role of RGB color channels is investigated in histopathology image classification by extracting nuclear and global image features across these color channels. Third, instead of analyzing various colour spaces a number of feature measures are explored from spatial and frequency domain to encounter maximum diversity. The individual and combined effect of a large number of statistical, structural and spectral feature measures are analyzed including co-occurrence matrices, run-length matrices, local binary patterns with Fourier transforms, morphology features and intensity features. Fourth, an extensive investigation of rank-based feature selection schemes is performed and proved that elitism is not an optimal strategy for feature selection in histopathology image classification. An abstract feature i.e. an optimal combination of functionally collaborating features having implicit linkages is identified based on classification accuracy through evolutionary search process. Fifth, a number of classifiers are explored and an automatic selection of parameters of classification model (classifier and classifier’s parameters) is performed through Genetic Algorithm based evolutionary technique. The experimentation is performed on images of grade-I benign meningioma four subtypes (meningothelial, fibroblastic, transitional and psammomatous) and pre-invasive breast lesions four classes (usual ductal hyperplasia (UDH) and three nuclear grades of ductal carcinoma in situ (DCIS)). The proposed frameworks achieved the promising classification results for four meningioma subtypes and breast lesions grades. In most of the cases, optimal sets of features obtained from the combination of three color channels and classified through linear support vector machine classifier presented the highest classification accuracy. The extraction of nuclear texture in spatial and frequency domain presented promising classification results.