ہم سے وہ بدگماں نہ ہو جائیں
کوششیں رائیگاں نہ ہو جائیں
اپنے اشکوں کو کب تلک روکوں
خوف یہ ہے رواں نہ ہو جائیں
یاالٰہی! یہ راحتیں اتنی
باعثِ امتحاں نہ ہو جائیں
اپنی آنکھوں کو آپ سمجھائیں
دل کی باتیں عیاں نہ ہو جائیں
پاس میرے نہ بن سنور کے آ
خواہشیں پھر جواں نہ ہو جائیں
راحتوں نے چھڑا لیا دامن
غم بھی نا مہرباں نہ ہو جائیں
قربتوں میں یہ ڈر رہا تائبؔ
اُن سے پھر دوریاں نہ ہو جائیں
Cardiovascular diseases (CVDs) are the top most cause of morality around the world. It is predicted that the number casualties from CVDs will increase to more than 24 million till 2030 people. Medicinal plants provide the major raw materials for medicine preparations. They are gaining high consideration due to their effectiveness and increasing cost of modern medicines. Many successful drugs are plant based, including aspirin from the willow bark, morphine from opium poppy, quinine from the cinchona bark, and digoxin from the foxglove. According to World Health Organization (WTO), ~70% to 80% of people around the world rely on herbal sources for the treatment of their disease. Plant sources are endorsed due to the fact that they contain an optimal amount of antioxidants and phytochemicals that help to avoid and treat many diseases. Phoenix dactylifera L. Particularly Ajwa variety, is the most rich in phytonutrientsthat can benefit to control many cardiovascular diseases. It contains6 vitamins (vitamin A, C, B1, B2, B3 &riboflavin), high amount of fibers, Potassium, Magnesium and 23 amino acids which play a healthy role towards hypertension, muscular contractions, and blood pressure control. It has been studied that Niacin (B3) helps to control cholesterol and low density lipoprotein levels (LDL), as high cholesterol is the one of the main cause of cardiovascular diseases so, Ajwa could be a vital regulatory source. According to the findings of Sabbah M. Et al, Ajwa extracts significantly improved the DNA integrity and also reduced the cardiomyocytes congestion, edema and the cellular stress wielded on cardiac muscles resulting the restoration of cardiomyocytes architecture in Doxorubicin (DOX) induced cardiotoxicity in rats. Research done by Alqarni et al, proves that Ajwa extracts has successfully decreased the LDL‐C, VLDL‐C, and triglycerides concentration. Additionally, treatment with ajwa pulp also improved the HDL‐C level and antioxidant enzymes activity. In another invivo study, Ajwa preparation has successfullydecreased the diclofenac-induced pulmonary and hepatic instabilities. Vitamin-K play important role in blood coagulation, and in case of anticoagulant therapy, activity of vitamin-K controlled by drugs (warfarin) that sometimes causes serious side effects. According to the reported data, Salicylic acid is the vitamin-K antagonist and has capability to block the action of vitamin K during the coagulation pathway. Dates contain ~3.75 to 4.50 mg/100 g of salicylic acid. Thus, providing anticoagulation effect too. So, the limelight of the reported data provides an enough reason that plants can be used as primary source of drug designing for the cardiovascular disease. They hold true momentum to address the increasing healthdiseases, which cannot be lost to distraction or apathy. Fight against the burden of CDVs, is affecting all countries and specially, under developing and the poor countries.
Since global powers shape politics of the world for their self-interests and United States is the most influential power in the world today. Therefore, US foreign policy and its relations with other nations, especially with Pakistan in the South and west Asia is a prominent theme of international politics. So, this study helps us to understand the nature of US relationship with Pakistan i.e a cyclical pattern of cooperation and estrangement. This also enables us to understand the internal and external forces, which determine the cyclical pattern of relationship between the two countries during cold-war, post-cold-war and post 9/11, 2001 relations. It also sharpens insight regarding the transitional change in the relationship between Pakistan and US, i.e. Patron-Client relationship to Estranged-Client Relationship, due to transformation in international system. This dissertation also puts light on how such uneven interactions have affected the politics and security of Pakistan and expected future path of interaction. This also attempts to set forth a theoretical foundation that helps in understanding the identity (security related) construction that accompanies the Pakistan’s foreign policy collaboration with US. Major focus of the research is on the period of eight years i.e. 9/11, 2001 to 2008 that covers president Georg W. Bush junior’s administration in US and Gen. (Rtd) Musharraf’s regime in Pakistan.