دل کی بات نہیں سنتا ہے
میں نے کہا اجازت ہو تو
دل کی بات کہوں اک تم سے
اُس نے کہا نہیں رہنے دو
Pseudomonas aeruginosa is a widespread organism, caused severe nosocomial infection in human and associated with multiple drug resistance (MDR)Objective: The present study was carried out to observe current antimicrobial resistant pattern of Pseudomonas aeruginosa in Lahore and to detect the Metallo-beta-lactamase (MBL) gene in carbapenem resistantPseudomonas aeruginosaMethods: By screening 360 samples total 123 Pseudomonas aeruginosa was identified by standard microbiology techniques such as microscopy and biochemical testing. The isolated Pseudomonas aeruginosa was evaluated for drug resistance by disc diffusion method and polymerase chain reaction(PCR) was used to identify the carbapenem resistance causing gene (bla-VIM and bla-IMP) Results: Following antibiotic resistant pattern was observed, Gentamycin (59.00%), Ceftazidime(58.7%), Ceftriaxone (58.00%), Cefotazime (57.0%) and Ciprofloxacin (55.00%). Resistance rates to carbapenem group of antibiotics is Doripenem (30.5%) Meropenem(31.0%) and Imipenem (28.0%). Out of 123 samples of Pseudomonas aeruginosa, 28 isolates were found resistant to carbapenem group of antibiotic which was supposed to be highly sensitive for this bacterium. Molecular based identification of resistance genes showed that bla-IMP gene was present in 32.1% (09) and bla-VIM was found positive in 17.8% (04) samples. Metallo-beta-lactamasesproducing genes (bla-VIM and bla-IMP), amongcarbapenem resistant Pseudomonas aeruginosa were detectedin 28.1% of samples. If other carbapenem resistant gene were also included this number might be higherConclusions: PCRbased test should be included in routine laboratory examination for quick detection of the resistancecausing genes.
Value crisis in corporate world around the globe significantly increased the need to find new management paradigm to deal with existing ethical dilemma. Study investigates inherent flaws of the contemporary corporate management in general and value based corporate management in particular. Study identifies that weaknesses of current corporate management stem form two main factors first lack of values and ethics and second loss of leadership integrity. A questionnaire containing 50 items was developed and validated. Study was carried out by taking a sample of 302 managers from manufacturing and service sectors of Pakistan. Data was processed and analyzed in SPSS and VPLS. Results of the study indicate that there is significant and positive relationship among values and ethics, managerial performance and welfare and protection of all stakeholders of organization. Findings suggest that management by example is a better management paradigm to curb many ethical ailments of modern enterprise. The current study developed ‘Islamic VBM Score’ to assess VBM practices in an organization from Islamic perspective. Furthermore, results suggest that Islamic leadership tries to take the organization towards total value based management through ensuring welfare and protection for all stakeholders of organization including shareholders, employees, customers and society at large. This study concludes that Islamic leadership in value based corporate management theory ensures satisfaction of all stakeholders of organization.