قرآن کریم میں مذکورہ انبیا ء کرام کے واقعات سراغ رسانی

Intelligence system is considered to be one of the important tools used by military and civil secret agencies to defend and strengthen a nation. Intelligence system is thought to be one of the oldest studies of known history. Intelligence system consists of correct and accurate information, gathered after great struggle and facing difficulties. This department is related to both peace and war. Intelligence is a basis of formulating all military strategies and plans. The importance of Intelligence system both in day to day life and as a nation cannot be overemphasized. This article narrates the history of espionage, which is as old as the history of mankind itself. Five thousand years ago, the Egyptians has a well-organized secret service. In the ancient western country, it was called as; hakim’, in Spain (Undles) as ‘Sahib al Madina’, in Tunis as ‘Ray’ and in Iran the as “Areef”. Nowadays it is known as ‘Muqadama-Tul-Haaraat’, Salaf-Us-Saliheen calls its “Shurtaa” and some calls it as ‘Sahib al-us-us’ as they use to move throughout the night to look for anti-state elements. The first ever victim of intelligence warfare was Hazrat Adam (A) where Satan revolt against him. Similarly, the incident of Hazrat Yousaf (A) is the indication of old age practice of espionage. Due to jealousy, his brothers sold him as slave and told their father that he has been eaten alive by a wolf. Hazrat Musa (A) had his network of espionage. Even birds had been used for spying, like in the case of Hazrat Suleman (A) where he was informed by the hopp bird about the Queen of Saba. The study of the Bible reveals that instead of Hazrat Eessa (A), Yehuda Skruti was crucified but still nobody knows for sure that whether he was a true follower of the Jesus or was an implanted agent of the Romans Intelligence Agency. Anyhow, Bible declared him as a Roman spy. The ongoing tribal wars in ancient Arabs further emphasized this activity. The rest of the world had already well developed intelligence system. But in Arab, it was in its development phase and it was the Holy Prophet (PBUH) who got it from his ancestors and developed it. In addition to the intelligence systems of the early prophets, the relevant events in the realm of Nijashi of Habsha and Alexander the Great, have been narrated in this article.

Study of Organometallics

A series of novel and biologically potent organometallic complexes using Nheterocyclic carbenes (NHCs), cephalosporin derivatives, quinolilone derivatives, vitamins and antiviral molecules as ligands has been synthesized. The geometry of the synthesized ligands and their metal adducts are done through state of the art spectral tools like NMR (1H, 11B, 19F) UV/Visible and FT-IR. It is confirmed through these spectral studies that in the NHCs the metal is bonded through the active carbine side while in other classes metal is bonded through either oxygen or through nitrogen in some cases. After synthesizing the ligand and the metals molecules are subjected to a variety of biological tests like, antibacterial, antifungal, antioxidant, Positron emission topography and ADMET studies in order to evaluate the bio-potential of the synthesized molecules. Some of the selected compounds are screened with various microorganisms like Gram positive bacteria, Gram negative bacteria and with some fungi. The results obtained are quite impressive, it can be shown that ligands in its free state possess less activity while it is clear from the results that their activity shifts to greater extent while treated with various metals. This clearly shows that metals are responsible for the bioactivity. Further, the molecular docking study was also carried out for Tin(IV) Schiff bases complex in order to correlate the biological experimental results. As in the parent study the Tin(IV) Schiff base complexes derived from piperenol and Entecavir exhibit excellent biological results which were further confirmed through molecular docking study. For some of the molecules ADMET study was also carried out in order to check/correlate the experimental data. ADMET study also confirmed the experimental results. It can be concluded from the present study that the organometallic complexes/metal molecules can serve as potent agents in curing many diseases and may prove their role as future metal base drugs.