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Association of G196A rs6265 Gene Variant of BDNF With Obesity Associated Depression

Thesis Info

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Author

Sehrish Imtiaz

Department

Department of Bioinformatics/Biosciences

Program

MS

Institute

Capital University of Science & Technology

Institute Type

Private

City

Islamabad

Country

Pakistan

Thesis Completing Year

2019

Subject

Bioinformatics/Biosciences

Language

English

Link

https://thesis.cust.edu.pk/UploadedFiles/Thesis.pdf

Added

2021-02-17 19:49:13

Modified

2023-02-17 21:08:06

ARI ID

1676709387859

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ہاتھ ہاتھوں میں دلربا دے دو

ہاتھ ہاتھوں میں دلربا دے دو
ایک بیمار کو شفا دے دو

لڑکھڑا کر میں گرنے والا ہوں
اپنی بانہوں کا آسرا دے دو

منصفو! میرا جرم الفت ہے
جو بھی چاہو مجھے سزا دے دو

پھر نہ باہم رہے گی کچھ تلخی
تم جو اپنی مجھے انا دے دو

پھر نہ روئے گا عمر بھر تائبؔ
تم جو تھوڑا سا حوصلہ دے دو

برما میں روہنگیا مسلمانوں کے مذہبی مسائل اور اس کے اسباب و اثرات

Buddhism is dominated by such other characteristics as sympathy, pity, and kindness. Furthermore, it forbids all kind of cruelty, violence, murder, brutality, and giving pain to any living creature. However, contrary to his teachings, the way his followers have targeted the Rohingya Muslims with violence and atrocities only shows how little they follow Gautama Buddha. Right from the independence of Burma, Buddhists,  declaring Muslims as a threat, started their genocide, which involved attacking their mosques, their homes, dishonoring Muslim women, and harassing the Muslims without any reason. This compelled Muslims to leave their homes and migrate. The recent wave of violence, starting in June 2012,  seriously affected the Muslim majority province of Arakan. Keeping in mind, Arakan is one of the fourteen Burmese provinces, where Islam have ruled since the time of Isalmic Caliphate. Unfortunately, in 1784, Burmese Prince Bodo Phia violated this garden of Islam by carrying out Muslim genocide. He banned all symbols of Islam such as pilgrimage, sacrifice,  prayers, Friday and Eid Prayers, and preaching. This study points out the religious problems and issues of Muslims believers in Arakan including its impact, causes and consequences on their lives. The analytical research Methodolgy has been adopted in this studty.

Assessment of Physico-Chemical and Molecular Diversity in Capsicum Annuum L. Germplasm

Assessment, identification and characterization of germplasm is a significant link among the conservation, utilization and improvement of plant genetic resources. In current investigation 133 genotypes of (Capsicum annuum) were evaluated at morphological level for 9 quantitative and 21 qualitative traits, the comprehensive approach of these studies delivers useful information on variability of traits for consecutive two years 2016-17. The genotypes were also evaluated for macro, micro elements, antioxidants and proximate analysis. But very little variation was found at proximate level. Among minerals potassium, iron and calcium showed wide range of variability. Potassium ranged from 209.0 to 352.3 mg/100g. Iron displayed variation ranged from 56.2 to 139.4 mg/100g and calcium content varied from 20.2-135.2 mg/100g. Additionally a precise, simple and accurate HPLC technique was used for determination of antioxidants (ascorbic acid and beta carotene) showed wide variation. Ascorbic acid ranged from 85.99 to 317.65 mg/100g whereas beta-carotene varied from 129.37 to 1318.07 ug/g. Furthermore, capsinoids, unique feature of Capsicum annuum were also determined by HPLC technique, exhibited immense variations for capsiacin ranged from 5.96 to 3924.27 ug/g, whereas range of dihydrocapsiacin varied from 1.96 to 1428.05 ug/g among diverse genotypes. Cluster analysis exposed grouping of genotypes based on similarities indices regardless of geographical origin. Correlation of yield with agronomic trait presented complex pattern of association. Principal component analysis was performed to observe the percentage contribution of each parameter to total biochemical variability. The first principal component (PC1) elucidated 64.53 % of variation. (PC2) exhibited 32.5 % of variability among genotypes for all biochemical traits. Germplasm displayed substantial variation, on the basis of agronomic performance, 20 genotypes were identified for future breeding either through direct exploitation or involved in the improvement of Capsicum through breeding programs. For better understanding molecular diversity was tested through 29 SSR markers to detect polymorphism in 133 genotypes. An average of 2.0 allele per marker was perceived. In the conclusion 28 characters studied in a set of 133 genotypes displayed a wide range of variability for yield, single fruit weight, plant height, potassium, iron, calcium, ascorbic acid, beta-carotene and capsinoids contents.