ظفر احمد صدیقی مرحوم
( ڈاکٹر محمد اشتیاق حسین قریشی)
۴؍ اکتوبر ۱۹۸۰ء کو جناب ظفر احمد صدیقی وکیل، سکریٹری دینی تعلیم کونسل کا انتقال اپنے آبائی وطن راما بھاری تحصیل بسواں ضلع سیتاپور میں ۳۰:۷ بجے صبح کو طویل علالت کے بعد ہوگیا، دفتر دینی تعلیمی کونسل لکھنو میں وہ حضرت مولانا علی میاں صاحب کے ایماء پر ۵۹ء سے مقیم تھے، یہ ایک طرح سے ان کا وطن ثانی بن گیا تھا، اپنی وفات سے ۴۸ گھنٹے پہلے اس حال میں رخصت ہوئے تھے کہ انہیں ہوش نہیں تھا، بلڈ یوریا کی وجہ سے ایک ہفتہ سے غفلت تھی، احباب اور رفقاء نے اسی وقت یہ سمجھ لیا تھا کہ برسوں کا یہ تھکا ہوا مسافر اور ساتھی اب لکھنؤ واپس نہیں آئے گا، سیتاپور سے فون پر اطلاع ملی، وہ سب سے جدا ہوکر اﷲ کو پیارے ہوگئے، ان کی اہلیہ کا انتقال سال بھر پہلے ہوچکا تھا، اولاد کوئی نہیں تھی، بھتیجوں کو اولاد سمجھتے رہے، جن کو اپنی نگرانی میں تعلیم دلائی، ان کے حقیقی بھائی کا قیام رامابھاری میں ہے، جہاں ان کا خاندان صدیوں سے آباد ہے۔
ظفر صاحب نے تعلیم مسلم یونیورسٹی میں پائی، ان کا قیام میکڈانلڈ ہوسٹل میں تھا، تعلیم کے بعد سیتاپور میں وکالت شروع کی ان کا شمار وہاں کے کامیاب وکیلوں میں تھا، ۴۷ء سے پہلے مسلم لیگ سے وابستہ رہے، تبلیغی کاموں سے بھی شغف رکھا، لیکن جب قاضی محمد عدیل عباسی مرحوم نے ۵۹ء میں بستی میں بچوں کی تعلیم کے سلسلہ میں کنونشن کیا اور وہاں یہ فیصلہ ہوا کہ اس سلسلہ میں مستقل کام کی ضرورت ہے، تو حضرت مولانا علی میاں صاحب کے ایماء پر ظفر صاحب نے اپنی کامیاب وکالت چھوڑ دی اور دینی تعلیمی کونسل کے کاموں کے لئے اپنے کو وقف کردیا، پھر ان کو ایسی...
Background of the study: Mechanical pain of musculoskeletal origin, known as nonspecific LBP (NSLBP), has symptoms that change depending on the type of physical activity [1]. About 85% of her LBP patients present in primary care settings are NSLBP patients.
Methodology: Randomized control trial (RCT) conducted between between January 2020 and October, 2021, Rawal General and Dental Hospital and Al-Nafees, the hospital in Islamabad. Thirty patients were included in the study. Two participants were discontinued. There were two groups of patients i.e., 15 patients in the KT group and 13 patients in the DN group diagnosed of NSCLBP by orthopedic surgeon and referral to outpatient physiotherapy clinic. The Sample size was calculated using the OpenEpi scale. The Consent form was filled out by the participants before the initiation of the study. Pain Rating Scale, Roland-Morris Disability Index Questionnaire (RMDQ) and Global patient rating scale (PGR) were assessed at baseline, two weeks post-intervention and four weeks post-treatment.
Results: Before treatment, there were no differences between the groups for PNRS, RMDQ and PGR. Both DN and KT produced significant improvements in all baseline measures (PNRS, RMDQ and PGR) after two weeks and four weeks of treatment (p<0.05). Considerable improvements were observed in all variables in both groups after treatment. However, Statistical analysis ANOVA showed no significant differences in almost all measures between groups. (p>0.05).
Conclusion: Kinesio-taping is as effective as DN in managing back pain. When treating back pain, adding DN or KT to your exercise program can make a significant contribution to your treatment.
Complete genome of HBV is almost 3200 base pair long having semicircular shaped double stranded DNA, so far classified into ten genotypes labeled A to J, about 40 sub genotypes and 4 serotypes adr, adw, ayr, ayw. Distribution of HBV genotype D and sub genotype D1 is mostly predominant in Pakistan and India about more than 80% among all genotypes of HBV. While it is less dominant in China where genotype B and C predominates. Focus of this study is the computational analysis of HBV genotype D sub genotype D1 comprising Sequence analysis done using PROBCONS, Phylogenetic analysis performed by MEGA software program, Gene structure analysis using GSDS 2.0 version and Protein structure analysis using BLASTP and SWISS-MODEL.For all these analysis sample of 54 complete genome sequences of HBV genotype D sub genotype D1 were used. Representation of 3 selected countries was subject to the availability of data at Genbank. Six complete genome sequences were obtained from Pakistan 14 from China and 34 sequences were from India. Sequence alignment shows less than 4% divergence in reported sequences from Pakistan, India and China. C and X genes showed divergence of less than 3%. While comparison over the S gene showed similarity ratio of genotype D sub genotype D1 is 97?98%. Phylogenetic analysis suggested that Pakistan HBV, complete genome isolate have the closest evolutionary relationship with its neighboring countries China and India. Sub genotype D1 isolates from China (HQ833466) and Pakistan (AB583680.1) share same ancestor. Gene structure showed coding region exons of ?P? gene is largest about 75% of the gene size while gene ?S? has 2nd largest coding region. However, ?C? and ?X? genes have one smallest exon. Using BLASTP Protein structure showed that similar kind of proteins from different sequences share identical structure format. X proteins were 92% identical, both of Polymerase and Middle S proteins were 99% identical, large surface and pre-core/core proteins have 98% similar structural features relative to its own type. Results from all three X proteins homology models using SWISS MODEL revealed GMQE=0.1. Global and local quality estimate scores including Z-scores for QMEAN CBeta, All Atom, Solvation and Torsion Energy scores were similar indicating good quality, accuracy and reliability of predicted models. 3D visualization showed similar structures and Ramachandran plots showed high percentage of protein residues into favorable region for X Protein Models.