مولانا عبدالصمد رحمانی
تین مہینہ کے سفر کے بعد جب ۳/جون کوبحمداﷲ بہمہ وجوہ خیریت و عافیت واپسی ہوئی توجن احباب اوربزرگوں کے انتقال پرملال کی خبر سے سخت افسوس اوررنج ہوا ان میں مولانا عبدالصمد صاحب رحمانی بھی تھے۔مولانا ان اکابر علم وفضل اوراصحاب ورع وتقوی میں سے تھے جن کے دم سے اسلام کی روحانی اوردینی واخلاقی عظمت کی آبرو قائم ہے۔ ان کی استعداد بڑی پختہ تھی، مطالعہ وسیع، نظر دقیق اورفہم ثاقب رکھتے تھے۔ یوں تو سب ہی علوم دینیہ و مروجۂ مدارس عربیہ سے ان کو قلبی لگاؤ تھا لیکن فقہ اورحدیث سے ان کوزیادہ دلچسپی اور مناسبت تھی۔ جب گفتگو کرتے تھے توان کی باتوں سے رسوخ فی العلم کے ساتھ سنجیدگی ٔرائے،ذہانت اورتوازن فکر کے بھبکے آتے تھے۔عملاً بڑے قناعت پسند اور درویش صفت بزرگ تھے، ہرچیز میں سادگی اور بے تکلفی ملحوظ رکھتے تھے۔ صاحب درس اورصاحب تصنیف وتالیف بھی تھے۔ ملک کی تحریک آزادی کے ہراوّل دستے میں تھے لیکن آزادی کے بعد ملک میں جوحالات پیش آئے اورجن کا سلسلہ اب بھی جاری ہے، انھوں نے بعض دوسرے مجاہدین وطن کی طرح ان کو اس درجہ دل شکستہ اور مایوس کردیا تھا کہ وہ سب کچھ چھوڑ چھاڑ گوشہ نشین ہوگئے تھے۔ چند برس سے مجموعۂ امراض واسقام تھے اوربہت کمزور ہوگئے تھے، آخر وقت موعود بھی آپہنچا۔اﷲ تعالیٰ مغفرت وبخشش اور رفع درجات کی نعمتوں سے سرفراز فرمائے۔آمین [جون۱۹۷۳ء]
Mysticism is the practice of religious ecstasies, together with whatever ideologies, ethics, rights, legends, and magic may be related to them. It may also refer to the attainment of insight in ultimate or hidden truth, and to human transformation supported by various practices and experiences. Sufism also known as Tasawwuf variously defined as Islamic mysticism. The inward dimension of Islam is mysticism in Islam characterized by particular values, ritual practices, doctrines and institutions which began very early in Islamic history and represents "the main manifestation and the most important and central crystallization of mystical practice in Islam. Practitioners of Sufism have been referred to as "Sufis". Sufis have been characterized by their asceticism, especially by their attachment to dhikr, the practice of remembrance of god, often performed after prayers. This article describes of the reality and fact of mysticism, its verbal and literal meanings, and its historical background and also describes its regional division and causes of Tasawwuf. It also analyses of the objections and its answers of which occurred on it.
Inflammatory diseases are associated with a number of ailments; these disorders could be life threatening like hepatitis, cancer, trauma injury while some decreases the quality of life such as rheumatism, arthritis, tuberculosis etc. Oxa and thiazoles, having unparalleled share in pharmacological activity of especially anti-inflammatory, have arisen as superb templates in drug discovery. Their unique attributes have instigated synthetic chemists to access their innovative analogues by efficient and viable strategies. Insightful insertion of other heterocyclic cores, bicyclic rings and other active functionalities at appropriate sites has greatly enhanced their diversified bioactivities. This research endeavor is made to synthesize some novel anti-inflammatory agents based on oxa/thiazole via green protocol. Hence synthesis of new derivatives of oxa and thiazoles by novel routes focusing green strategy such as DES mediated preparation were carried out by adopting Hantzsch approach. For this purpose, ketones containing simple alkyl to pretentious alkyl functionalities such as tetrahydrocarbazoles and aryl moieties like phenyl and coumarin were used. Besides this, novel amide and thioamide analogues were also synthesized by functionalizing established bioactive heterocycles at their N position and the second step is annulation of these analogous with a series of bioactive ketones. A series of novel oxa and thiazoles each comprising twenty one compounds were synthesized. All new molecules were screened for in vitro anti-inflammatory potential by HRBC membrane stabilization method. Precursors were also subjected to antiinflammatory screening and only those were employed for the synthesis of oxazole and thiazoles which were found comparatively potent. N N NH 2 X R 1 O CH3 N N X R 1 N H X N R 1 N Oxa/ thiazoles N H R H X 2N N R H X 2N Green / Conv. Precursors Characterization of all of the innovative derivatives was done by analytical techniques like FTIR, 1HNMR and MS and CHNS analyser. Compounds 110, 111, 113d, 113b, 113g, 114a, 114b, 114c, 114f, 115b, 115e, 115f, 116d, 117b, 117c, 118a, 118b were found to possess best anti-inflammatory activity.