سجاد، ابوالمحاسن محمد، مولانا
سجاد کی یاد
۲۳؍ نومبر ۱۹۴۰ء اور ۲۱؍ شوال ۱۳۵۹ھ کی سہ پہر تھی کہ پھلواری سے مولانا ابوالمحاسن محمد سجاد نائب امیر شریعت بہار کی وفات کی خبر آئی، دل کو یارائے ضبط نہ رہا، آنسوؤں کے چند قطرے زمین پر گرے، وہ زمین جواب مرنے والی کی خوابگاہ ہے، ابھی قلب میں یہ ہمت بھی نہیں کہ جی بھر کر ماتم کروں اور دل کے شیون کو سپرد قلم،
دریں آشوب غم عذرم بنہ گرنالہ زن گریم
جہانے راجگر خوں شد، ہمیں تنہا نہ من گریم
مرنا اور جینا دنیا کے روازنہ کے کاروبار ہیں، کون نہیں مرا اور کون نہیں مرے گا، آج وہ، کل ہماری باری ہے، اس پر بھی عزیزوں اور دوستوں کی موت پر رونے والے روتے ہیں، ان کی دائمی فراق پر ماتم اور فریاد کرتے ہیں، ان کی ایک ایک خوبی کو یاد کرکے ان کا نوحہ پڑھتے ہیں۔ عام حالت یہی ہے، لیکن بعض موتیں ایسی بھی ہوتی ہیں کہ ان کی خبر سن کر زبان بند ہوجاتی ہے، آنسو سوکھ جاتے ہیں، دل کی حرکت بڑھ جانے کے بجائے گھٹ جاتی ہے، اندر ہی اندر گھٹن محسوس ہوتی ہے، مگر جی نہیں چاہتا کہ کچھ بول کر دل کی بھڑاس نکالئے اور آنسو بہا کر غم ہلکا کیجئے، مولانا ابوالمحاسن محمد سجاد مرحوم کے سانحہ کا مجھ پر بالکل یہی اثر ہوا، دن بیت گئے ہفتے گزر گئے، مہینے ختم ہوگئے مگر زبان نہ کھلی اور دل کی امانت قلم کے سپرد نہ ہوسکی، عزیزوں اور دوستوں کو تعجب ہے کہ میرا قلم جو احباب کے سوگ میں ہمیشہ اشک زیر رہتا ہے، اس پہلی دفعہ وہ اپنے فرض کو کیوں بھولا ہے، مگر یہ کیسے بتاؤں کہ اس ناگہانی اور غیر متوقع غم سے مجھے کیوں چپ سی لگ گئی، ہر...
A judge should be honest, transparent, free and fair. He should always respect law. The question arises that if a judge who disrespects law and makes unbalanced decisions: as a result of which people get affected then will he or she be penalized? The Ḥanafi Scholars opine that if a judge passes a wrong decision intentionally, he should be penalized from his own property. Because in Islamic jurisprudence, judiciary owns a supremacy over the masses and everyone irrespective of the position is equal and has to obey law. Whether he is a judge or a commoner, he has to follow the rules and regulations as prescribed by law. In practice, Pakistani judges are not held responsible for making a wrong verdict. Our judges make judgments on the basis of already manipulated evidence. A judge bars himself from the responsibility of collecting evidence. Similarly, if a judge has developed personal grudges with the criminal then the criminal reserves right of appealing the higher court where the decision is reviewed and rectified. In such situation, there is a compulsion between the legal maxim "وَالْأَصْلُ عَدَمُ الضَّمَان" and the Pakistani laws. However, Ḥanafi jurisprudence and Pakistani Laws are not in accordance with each other. This study concentrates upon the nature of punishment and tort to be applied on judges in case of making a decision based on falsehood. It is suggested that Pakistan’s Judiciary should be reread as that the already in-practice system does not comply with the standards of Islamic teachings.
Introduction: Molecular characterisation of the breast cancer has allowed for targeted therapies that are improving outcomes. The gains achieved by these treatments have fuelled the search for other targets, including cyclin-dependent kinase inhibitors such as p21. p21 expression in breast cancer has been shown to be variably associated with clinical and pathological parameters in different populations. It is possible that either methodological or biological differences underlie these variations.
Objective: The current study sought to determine the association of p21 expression and clinico-pathological parameters in breast cancer patients at the Aga Khan University Hospital in Nairobi, Kenya.
Methods: Clinically annotated tissue samples were obtained in a consecutive fashion. Specimen were immunohistochemically stained for p21 expression with clinicopathological data extracted for corresponding cases. p21 expression was assessed against age, parity, menopausal status, body mass index, hormonal receptor status, tumour size and grade. Distribution of mean p21 score was assessed for normality and data were analysed using Kruskall-Wallis test, chi-square and Fisher's exact test at an alpha level of 0.05. They were presented in form of tables, charts and photomicrographs.
Results: Ninety-eight cases were included in the study. Mean age was 47.55 years with mean parity 2.96 live births. A slight majority of patients were pre-menopausal (56.3% versus 42.5%). Average body-mass index was 29.69 kilograms per square metre. Majority of patients had invasive ductal carcinoma (87.6%) that was moderate-to-high grade (92.7%), 2 centimetres or larger (95%), with lymphovascular invasion (70.4%), and vi hormone-receptor positive. Mean expression of p21 at 1:100 dilution was approximately 20% was statistically significant with tumour size.
Conclusion: The findings of the current study demonstrate a possible association of p21 expression with tumour size. The demonstration of a trend towards p21 loss with increasing body mass index may benefit from exploration with a larger dataset.