دین اسلام کی ترویج میں دعوت و تبلیغ کی اہمیت: ایک تحقیقی جائزہ

Before the birth of the Holy prophet, human society yet again got at the verge of destruction due to apostasy and ignorance. The Holy Prophet introduced Islam to the sinking humanity. For spreading its message "Dawat"; Calling (To God) was made everybody's job. As Allah says in the holy Quran: "The Believers, men and women, are protectors, one of another: they enjoin what is just and forbid  what is evil: " (9: 71). There are three fundamental groups of preachers. The first is the "Dawat" of common people to others. It is imperative for such a preacher that he himself should get the knowledge of religion through Islamic law and then communicate every virtue of it to his family, friends, neighbors and close relatives. The second is the place of Nobles. They include the commentators of the Quran, the narrators of the Prophet's Sayings, theologians and the learned scholars. The commentators of the Quran explain the meanings of the verses of the Quran keeping in view the conditions of the Quranic sciences. The narrators interpret the meanings of the Sayings of the Holy Prophet. The theologians or the learned scholars are entitled to discuss the Quran, Prophet's Sayings and the problems of the Islamic laws. The third is the place of the favorites. These people are the perfect successors of the Prophets. They have full control over the knowledge of laws as well as over the knowledge of mysteries. As Allah says: "and purify them", (one of the responsibilities of the Holy Prophet was to purify the souls). At a place it is said: "Truly he succeeds that purifies it" (91: 9). In this article research is done on "Calling (to God) and conveying His message".

Association Analysis of Dna Variants With Dyslipidemia and Cardiovascular Disease

The recent insight that inflammation due to enhancing level of TNF (Tumor Necrosis factor) alpha cause to increase in LDL and decrease in HDL that results in dyslipidemia, which further leads toatherosclerosis and cardiovascular disease. Tumor necrosis factor-a (TNF alpha) hasreported to perform a pivotal role in inflammation involving reactions that further tend to lead toward cardiovascular disease (CVD). Elevated levels of TNF alpha are found during observation, in acute and chronic inflammatory conditions, which include proatherogenic lipid profile (LDL, HDL). The prevalence of obesity and other related disease risk becomes high when luckily are influenced by the diet related transition, usually associated to the urbanization. This study was designed to investigate the individuals with dyslipidemia (n=50) and control group (n=50) with normal lipid profile. Blood samples were collected for lipid profile and genotyping analysis. TNFA -308 polymorphism was screened in both the disease and control group. Allele G was related with normolipidemic and allele A with risk. RFLP method was performed using NcoI enzyme for genotyping and then run on agarose gel. The allele frequency of the TNFA-308 polymorphism significantly different gender wise (P = 0.036). The genotyping data showed significant variation with respect to LDL levels (P = 0.026) in control and disease group. This study suggested that TNFA-308 can be potential marker for risk assessment, however exploration on a large cohort would add to the conclusion.