Immunological memory as the fundamentals of vaccines Immunological memory and vaccines

The immune system also called as the defense system involves many different cells that work as soldiers in an individual. These immune cells provide protection against various pathogens. For better protection of an individual the immune systems has the ability to memorize or remember the pathogen. This ability is known as immunological memory. With the help of immunological memory the immune memory cells remember the antigen and are prepared if there is an encounter with the antigen in future. The immunological memory can be developed against certain strains with the help of different types of vaccines. Such types of vaccines that are currently being used to save lives are, Live attenuated vaccines, Toxoid vaccines, Subunit vaccines, Glyco-conjugated vaccines, and Killed/Inactivated vaccines. These vaccine show different efficiency. Hence, the immunological memory generated after a single vaccination may wear off with time. Multiple numbers of shots are required for the development of long term memory. All these types of vaccines vary from each other in their manufacturing and also in their mechanism of providing long term immunological memory. They show many pros and cons but their advantages are greater than their disadvantages. Thus, are preferred to be used for the betterment of mankind.   

Onshore Offshore Software Process Model

Offshore software development model is one of the most successful development models being adopted by different worldwide organizations. The main reason behind the offshore development is the higher cost of the software development in the local industry. So the organizations take the projects from the local industry and send their projects to their offshore offices where development cost is significantly lower. In countries like Pakistan, India, Sri Lanka and Philippines etc, most of the software companies are working as offshore development offices. These software companies are using different software development methodologies like Waterfall, Spiral, Iterative, Incremental and Agile. The projects developed by these software companies face time, cost and quality constraints because of opting inappropriate software development lifecycles. A detailed study is conducted by gathering data from different offshore software companies in Pakistan and then based upon this data their common problems are identified. The major problems faced by the software companies in Pakistan include non static and ambiguous nature of requirements which cause the software developers to make certain assumptions. There is no direct interaction between the software developers and the clients, so the product developed is not an exact match of the client requirements and expectations. These issues are major bottleneck in delivering the quality software products in case of offshore development in Pakistan. We propose a new process model that addresses the needs of the onshore/offshore software development industry.