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Synthesis spectral analysis and pharmacological studies on new organic molicules containing 1- 2-furoyl piperazine moiety

Thesis Info

Author

Ghulam hussain

Department

Department of Chemistry

Program

PhD

Institute

Government College University

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Degree Starting Year

2012

Degree End Year

2015

Subject

Chemistry

Language

English

Other

CD is also available at PG Library

Added

2021-02-17 19:49:13

Modified

2023-02-17 21:08:06

ARI ID

1676711014142

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علامہ شبلی نعمانی

علامہ شبلی نعمانی تعمذہ اﷲ برحمۃ

(اکثر حضرات ہم سے علامہ مرحوم کے حالاتِ زندگی کے طالب ہیں، بہار اسٹوڈنٹس کانفرنس نے علامہ مرحوم پر سب سے بہتر مضمون نگار کے لیے انعام مقرر کیا، سوانح و حالات کے لیے اکثر اشخاص کے خطوط آتے ہیں، مطول لائف تو جب لکھی جائے گی، اس وقت اس مختصر رسالہ پر قناعت کرتے ہیں کہ منتظر احباب کو زحمت انتظار سے کسی قدر نجات مل سکے، اس مضمون سے پنجاب کے ان بعض اخبارات کی تحریروں کی تصیح بھی ہوجائے گی، جو حادثۂ وفات کی تقریب نے مولانا کے مرحوم کے سوانح زندگی کے متعلق انھوں نے لکھی تھیں)

          اسلام کا گہرا بادل ایک ہزار سال سے برابر ہندوستان کی اقلیم پر مصروف بارش ہے، کتنی بار بادل ابرنیساں بن کر برسا اور اس عجائب زار ہند کا دامن لعل و گہر سے بھرگیا لیکن ۱۸۵۷؁ء میں سارے ملک پر ایک خونی بادل نے تراوش کی، جس سے ہر جگہ تو خون برسا، لیکن کہیں کہیں خون کے قطروں کے بجائے سرخ یاقوت کے دانے برسے، جن میں سے ایک کو قدرت نے شبلی کے نام سے موسوم کیا۔

          ہندوستان کی سیر حاصل زمین نے علوم و فنون میں جو بالیدگی پیدا کی، اس کی تفصیل کا یہ موقع نہیں، تاہم مختلف دروں میں جو کلام و اسرارِ شریعت میں بحرِؔالعلوم اور شاہ ولی اﷲ، ادب و معانی میں قاضی عبدالمقتدر، ملک العلماء دولت آبادی، اور ملا محمود جونپوری، فلسفہ و منطق میں ملا نظام الدین اور ملا محب اﷲ بہاری، ادب و شاعری میں مسعود سعد سلمان، خسرو اور فیضی، تاریخ و خبر میں ضیا برنی، ابوالفضل اور آزاد بلگرامی کو پیدا کیا، لیکن اس کی آغوش کا آخری فرزند (شبلی) وہ تھا جو ملا محمود بھی...

جدید اور ہم عصر ریاستوں كے مقابلے میں خلافت راشدہ كی انفرادیت

During the Dark middle ages of Europe, The Holy Prophet Muhammad (PBUH) established the first ever Islamic state, in the Arab soil, at Medinah. The successors of the Prophet, known as Khulfa-i- Rashideen (the Glorious Caliphs) not only maintained it rather they extended with further development. The Caliphate was not only a model statefor the world but also a unique one with respect to its political appratus, principles and the governance. This paper discovers the same uniqueness of the Caliphate in past and modern perspective.

Biochemical Changes in Gestational Diabetes in Comparison to Healthy Pregnant Women

Biochemical changes in women with gestational diabetes mellitus (GDM) and healthy pregnant women (HPW) were studied. 103 GDM women and 97 HPW were selected and registered for the study from the admitted pregnant women of Gynea Ward of Khyber Teaching Hospital, Peshawar. Sociodemographic and other pregnancy related information, including monthly-income, age, body mass index (BMI), parity, previous history of gestational diabetes and family history of diabetes, were collected on a well-designed questionnaire. Fasting blood sugar (FBS), random blood sugar (RBS), glycosylated hemoglobin (HbA1c), hemoglobin (Hb), platelet count (PC), total cholesterol (TC), triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), liver function tests namely alanine amino transferase (ALT), alkaline phosphatase (ALP), serum bilirubin, renal function tests namely urea, creatinine, and hormones like insulin, prolactin, cortisol, triiodothyronine (T3), thyroxin (T4) and thyroid stimulating hormone (TSH) were determined by standard procedures using recommended kit for each procedure. The data were statistically analyzed using computer software, SPSS version 10. The mean monthly income of GDM and HPW was Rs.30845 ± 11107 vs Rs.28360 ± 11511, mean age was 34.01 ± 4.54 years vs 30.30 ± 5.86 years, mean BMI was 28.07 ± 2.90 kg/m 2 vs 27.30 ± 1.94 kg/ m 2 , mean parity was 5.44 ± 2.49 vs 4.95 ± 2.43, mean systolic BP was 114.80 ± 17.14 mm Hg vs 107.70 ± 19.40 mm Hg and mean diastolic BP was 86.50 ± 7.48 mm Hg vs 80.70 ± 10.02 mm Hg respectively. Age, BMI, systolic and diastolic BP was significantly higher (P<0.05) according to Pearson Chi- square test in GDM women as vicompared to HPW. The mean FBS, RBS and HbA1c of GDM women and HPW were 111.69 ± 8.70 mg/dL vs 86.59 ± 6.91, 145.45 ± 6.62 mg/dL vs 123.52 ± 9.37mg/dL and 6.58 ± 1.30 vs 4.95 ± 0.45 respectively. The FBS, RBS and HbA1c of GDM women were significantly higher than the HPW (P<0.001). The mean Hb concentration and PC of GDM women and HPW were 10.98 ± 1.12% vs 11.01 ± 1.03% and 226.31 thousand/mL vs 228.14 ± 37.61 thousand/mL. In lipid profile TC and TG of GDM group were significantly higher than the contol group (P<0.01). The mean TC of GDM and HPW was 206.01 ± 18.79 mg/dL vs 195.01 ± 24.15 mg/dL, TG was 190.12 ± 19.83 mg/dL vs 172.13 ± 21.66 mg/dL, HDL-C was 55.21 ± 8.20 mg/dL vs 56.20 ± 8.82 mg/dL and LDL-C was 93.13 ± 18.71 mg/dL vs 88.10 ± 16.36 mg/dL respectively. Liver and renal function tests of GDM women were not significantly different (P<0.05) from HPW. In liver function tests the mean ALT, ALP and serum bilirubin values of GDM women were 30.21 ± 12.47 U/L, 190.55 ± 22.20 U/L, 0.67 ± 0.41 mg/dL while of HPW were 29.64 ± 7.96 U/L, 189.95 ± 21.28 U/L, 0.58 ± 0.17 mg/dL respectively. In renal function tests the mean serum urea and serum creatinine values of GDM women were 23.70 ± 8.54 mg/dL and 0.82 ± 0.32 mg/dL while of HPW were 21.97 ± 6.16 mg/dL and 0.74 ± 0.15 mg/dL respectively. The mean insulin level of GDM women were 33.68 ± 3.69 μIU/mL, which was significantly higher (P<0.01) than the mean insulin level of HPW (29.80 ± 2.80 μIU/mL ). Among placental hormones the mean prolactin values of GDM women and HPW were 135.47 ± 9.83 ng/mL vs 131.80 ± 8.54 ng/mL and mean serum cortisol values were 734.9 ± 51.1 ng/mL vs 719.2 ± 54.7 ng/mL. The mean serum prolactin and serum cortisol values of GDM women were significantly higher (P< 0.05) when compared to HPW. No significant differences were viiobserved in the concentration of thyroid hormones. The mean TSH values of GDM and HPW were 1.72 ± 0.95 mlU/L vs 1.87 ± 0.83 mlU/L, mean T 3 values were 2.51 ± 0.62 nmol/L vs 2.62 ± 0.57 nmol/L, mean T 4 values were 103. 86 ± 14.74 nmol/L vs 105.38 ± 13.93 nmol/L. Cesarean sections (P=0.009), still birth rate (P=0.003) and macrosomic babies (P=0.001) were significantly more in GDM group.