Search or add a thesis

Advanced Search (Beta)
Home > Extraction, Structure Elucidation and Microbial Transformation of Protease Inhibitors from Medicinal Plants

Extraction, Structure Elucidation and Microbial Transformation of Protease Inhibitors from Medicinal Plants

Thesis Info

Access Option

External Link

Author

Muhammad Asam Raza

Department

Department of Chemistry

Program

PhD

Institute

Government College University

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Degree Starting Year

2007

Degree End Year

2010

Subject

Chemistry

Language

English

Link

https://library.gcu.edu.pk/Thesis/PhD/Asam25PhDChem07.pdf  

Other

CD is also available at PG Library

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676711017547

Similar


Loading...
Loading...

Similar Books

Loading...

Similar Chapters

Loading...

Similar News

Loading...

Similar Articles

Loading...

Similar Article Headings

Loading...

مولانا ابوالمحاسن محمد سجاد بہاری

آہ مولانا ابوالمحاسن محمد سجاد بہاری!
پچھلے دونوں ہندوستان نے اس خبر وحشت اثر کو نہایت رنج واندوہ سے سُنا کہ مولانا ابوالمحاسن سید محمد سجاد بہاری چندروز کی علالت کے بعد اس دنیائے فانی سے رخصت فرماگئے۔خبر چونکہ بالکل غیر متوقع طورپر ملی تھی اس لیے فرط حزن والم نے حیرت کی صورت اختیار کرلی۔ یعنی ہم یہ جانتے ہیں کہ ہماری بزم علم وعمل کاکوئی لعل شب چراغ گم ہوگیا ہے، لیکن اس احساس کے باوجود تحیر کی فراوانی ہم کو رخصت گریہ اورفرصت نوحہ بھی نہیں دیتی۔
مولانا ابوالمحاسن محامدِ اخلاق اورمحاسن فضائل کے جامع تھے۔فکر ونظر،علم و عمل، محنت ودیانت،تفقہ وتدبر،ایثار وجفاکشی،خلوص وﷲیت۔ان سب اوصاف کے بیک وقت جمع ہونے نے اُن کی ذات کوایسا گلدستۂ خوبی بنادیا تھا کہ وہ’’ای تو مجموعۂ خوبی بچہ نامت خوانم‘‘کا مصداق بن گئے تھے اوراُن پر’’ابوالمحاسن‘‘کی کنیت واقعی طورپر صادق آتی تھی۔ہندوستان میں کوئی قومی اورمذہبی تحریک ایسی نہیں ہے جس میں مولانا نے پورے جوش وخروش کے ساتھ حصہ نہ لیا ہو اوراس میدان میں اپنے ساتھیوں سے پیش پیش نہ رہے ہوں۔سب سے بڑی خوبی یہ تھی کہ اُن کادماغ نہایت دقیقہ رس اور معاملہ فہم تھا۔وہ موضوع فکر کے ایک ایک پہلو پربڑی سنجیدگی اورعالی ہمتی کے ساتھ غوروخوض کرتے تھے،اوراُس میں ایسی ایسی باریکیاں پید اکرتے تھے کہ لوگ حیران رہ جاتے تھے۔وہ عملاً بڑے جری اوربہادر تھے لیکن اُن کادماغ انتہائی جوش وخروش کے عالم میں بھی کبھی مغلوب نہیں ہوتاتھا۔جذبات کی گرمی کے ساتھ وہ ہر معاملہ پرٹھنڈے دل سے غور کرتے تھے۔حق یہ ہے کہ جماعت علما ہند میں وہ اپنی گوناگوں خصوصیات کے لحاظ سے گوہر یکتا تھے۔بقول کسی کے وہ ہرشخص کی قائم مقامی کرسکتے تھے لیکن اُن کی قائم مقامی کوئی نہیں کرسکتا۔فواحسر تاکہ ہماری انجمن کایہ گل سرسبدآج خزاں دیدۂ اجل ہوکرآغوش لحد میں آسودۂ...

Perceptions of students about the educational environment in Gomal Medical College Dera Ismail Khan

Introduction: Student satisfaction, academic performance, and learning effectiveness have all been related to the educational environmental perceptions in medical institutes. Students' opinions of their educational environment might help medical schools discover impediments and opportunities to improve student learning. Objective: To evaluate student perception related to current traditional and integrated learning methodologies in the Gomal Medical College Dera Ismail Khan. Methods:  The Dundee Ready Education Environment Measure (DREEM) questionnaire was provided to students of Gomal Medical College Dera Ismail Khan after approval from the institute. One hundred and sixty-one students out of 190 returned the questionnaire. The data was analyzed with SPSS 27.0. All questions were evaluated on a 5-point Likert scale. Results: The mean age of the students was 21.34±1.73 years. There were 89 (55.34%) males and 72 (42.66%) female students. The mean DREEM score among the students was 116.15±3.73. The highest score among the students was 153 and the lowest score was 42. The scores were higher among males than females. Conclusion:  The students were more positive and self-assured. Students had a more positive attitude toward teachers, the learning environment, and the atmosphere. However, they were lacking in social perceptionrequiring attention. KEYWORDS: Dundee Ready Educational Environment Measure, educational environment, medical institutes, perception

Molecular Markers of Susceptibility to Prion Diseases in Local Humans and Domesticated Bovids

This thesis presents the lacking information on genetic susceptibility of Pakistani population to human prion disease variants and of local domesticated bovids to Bovine Spongiform Encephalopathy (BSE). In study 1, a total of 909 unrelated individuals including 221 hemophiliacs representing all 4 major provinces of Pakistan were screened for M129V polymorphism and insertions or deletions of octapeptide repeats (OPRIs/OPRDs) using Polymerase Chain Reaction coupled with Restriction Fragment Length Polymorphism (PCR-RFLP). Concordance of the results of some PCR-RFLP reactions was also confirmed by dideoxy automated Sanger sequencing. The frequencies of M129V alleles (129M and 129V) and genotypes (129MM, 129MV and 129VV) were found in all 909 individuals to be 0.7101, 0.2899, 0.5270, 0.3663 and 0.1067, respectively. Deletion of 1 octapeptide repeat (1-OPRD) was detected in heterozygous state in PRNP of 10 individuals and in homozygous state in 1 individual. An insertion of 3 octapeptide repeats (3-OPRI) was found in 1 individual and an insertion of 1 octapeptide repeat (1-OPRI) in two individuals. Both 3-OPRI and 1-OPRI were present in heterozygous state and were linked to 129M allele. There were no significant χ2 differences between M129V allelic and genotypic frequencies of healthy individuals and hemophiliacs. However, M129V allelic and genotypic frequencies differed significantly between Pakistani population and East Asian and Western populations. Non-significant χ2 differences between M129V frequencies of healthy individuals and hemophiliacs suggest that individuals manifesting single gene disorders may provide naturally randomized samples for studies aiming at surveying the genetic variation. The combined excess of 129MM and 129VV homozygosity and the presence of 3-OPRI in 1 individual imply that Pakistani population may be susceptible to prion disorders. In study 2, a total of 236 cattle from 7 breeds and 281 buffaloes from 5 breeds were screened for E211K polymorphism and 23 bp and 12 bp indels employing triplex PCR. The E211K polymorphism was not detected in any of the animals studied. The 23 bp insertion allele was underrepresented in studied cattle breeds while the 12 bp insertion allele was overrepresented. Both 23 bp and 12 bp insertion alleles were overrepresented in studied buffalo breeds. Almost 90% of alleles were insertion alleles across all studied buffalo breeds. The average frequency of 23 bp and 12 bp insertion alleles across all studied cattle breeds was found to be 0.1822 and 0.9407, respectively. There were significant differences between Pakistani and worldwide cattle in terms of allele, genotype and haplotype frequencies of 23 bp and 12 bp indels. The higher observed frequency of 12 bp insertion allele suggests that Pakistani cattle are relatively more resistant to classical BSE than European cattle.