کواڑی دی کھچڑی
اک وار دی گل اے کہ اک بندہ اپنے پنڈ توں دوجے پنڈ کسے کم نال جا رہیا ہوندا اے۔ ایہہ پنڈ اوس دے پنڈ توں بہت دور ہوندا اے۔ سفر کردے ہوئے اوہنوں اک ویران جگہ اُتے شام پے جاندی اے۔ اوتھے اوہنوں کوئی گھر نظر نئیں آندا۔ جتھے اوہ رات گزار سکے۔ تھوڑا ہور فاصلہ کرن توں بعد اوہنوں دوروں اک گھر وچ روشنی نظر آندی اے۔ اوہ اوس روشنی ول سفر کر کے اوس گھر اپڑ جاندا اے۔ اوہدے بوہے اُتے دستک دیون توں بعد گھر وچوں اک مائی نکلدی اے تے اوس کولوں دستک دیون دی وجہ پچھدی اے۔ اوہ آکھدا اے کہ اوہ اک مسافر اے تے اوہنوں سفر وچ شام پے گئی اے۔ اوہ مائی نوں آکھدا اے کہ اج دی رات مینوں ایتھے سون دی اجازت دیو۔ میں سویر چلا جاواں گا۔ مائی اوس نوں اندر لے آندی اے تے سون لئی اک منجی دے دیندی اے۔
مائی بڑی کنجوس ہوندی اے اوہ اوس نوں کھاون لئی کجھ نئیںدیندی۔ کافی دیر بھکھے رہن توں بعد اوس نوں اک خیال آندا اے تے اوہ مائی نوں آکھدا اے کہ اماں توں کدے کواڑی دی کھچڑی کھاہدی اے۔ مائی آکھدی اے کہ نہیں پترا۔ اوہ مائی نوں آکھدا اے کہ میں اج تہانوں کھچڑی بنا کے کھوانا واں بس توں مینوں کواڑی تے برتن دے۔ مائی اوس نوں برتن دے دیندی اے۔ اوہ کواڑی نوں برتن وچ رکھ کے اوہدے وچ پانی پاندا اے تے برتن نوں چلہے اُتے رکھ دیندا اے۔
کجھ دیر توں بعد اوہ مائی نوں آکھدا اے کہ اماں جے ایہدے وچ تھوڑے جیہے چول تے تھوڑی دال پا دتی جاوے تاں کھچڑی بڑی مزے دار بنے گی۔ مائی اوس نوں چول تے دال دے دیندی...
Background and Aims: The study identified the risks of increased screen time on generation z considering two parameters i.e., insomnia and obesity and the moderating role of self-control.
Methodology: A cross-sectional study was conducted by convenient sampling technique. The survey only included people who were born between 1997 and 2002. The analysis of the effects of variables took into account only a few parameters. Discriminant validity and convergent validity was used to check reliability and validity while path coefficient analyzed the hypothesis.
Results: Binge-watching has positive significant impact on insomnia and obesity (p<0.05), and the self-control strongly effect the relationship of binge-watching, obesity and insomnia as a moderator (p<0.05).
Conclusion: Binge-watching caused insomnia and obesity while self-control in direct relation to obesity and insomnia controlled the prevalence rate. The moderating role of self-control showed that insufficiency of self-control during binge-watching led to obesity and insomnia. The outcome indicated that Generation Z needs to be encouraged to practice self-control through public health initiatives, social media, seminars, workshops, etc. At the same time, people need to be made aware of how binge-watching affects their health.
Keywords: Insomnia, obesity, self-control, screen time, technology, mortality, exercise.
The work embodied in this dissertation is mainly concerned with the isolation and characterization of natural chemical constituents having some biological importance. The isolated compounds were either new or previously been reported in the literature and they were characterized by various sophisticated spectroscopic techniques. The dissertation deals with purification and biological screening of secondary metabolites isolated from three indigenous medicinal plants of Pakistan namely Launaea nudicaulis, Launaea intybacea and Carissa opaca. The whole dissertation is divided into six chapters. The chapter 1 entitled as “Human Health and Role of Natural products” describes significance of terrestrial plants in Human life for the cure of various diseases, some FDA approved natural product drugs, natural products under clinical trials for FDA approval and new challenges in the field of natural products research. The second chapter entitled as “The Genus Launaea and its Importance” describes the genus Launaea, its economical, pharmacological and phytochemical properties. In this chapter the pharmacology of various isolates from the genus Launaea and biological activities of various species v or their extract has been discussed. Almost all secondary metabolites isolated up to date from the different species of Launaea have been described year wise. The third chapter entitled as “Phytochemical Investigations on Launaea nudicaulis” deals with the phytochemical studies on Launaea nudicaulis collected from Cholistan desert covers the isolation, structure elucidation and experimental detail of eight new and same number of known secondary metabolites. The methanolic extract of this plant was divided into n-hexane and ethyl acetate fractions. The n-hexane soluble part yielded four new sphingolipids: nudicualin A (112), nudicualin B (113), nudicualin D (114), nudicualin C (115) together with known compounds, 1-hexatriacontanol (109), elaidic acid (110), oleanolic acid (111) and β-sitosterol glucoside (67). The column chromatography of ethyl acetate part yielded four new compounds: a sesquiterpene lactone, nudicholoid (116), a diacetylene derivative, trideca-12-ene-4,6-diyne 2,8,9,10,11-pentaol (119), quinic acid derivative,cholistaquinate (121) and a flavonoid di-C-glycoside, cholistaflaside (123) along with four known compounds, ergosta-7,22-diene-3,5,6-triol (117), benzyl glucopyranoside (118), 3,7,12-trihydroxycholan-24-oic acid (120) and 20-hydroxyecdysone (122). Their structures were assigned by ID and 2D-NMR in combination with EIMS, HR-MS and FAB-MS techniques. Structures of the known compounds were determined by spectroscopic analyses and in comparison with the literature.