مولانا شیخ محمد عالم بدر میرٹھی
افسوس ہے ہماری بزمِ انوری کی ایک اورشمع فروزاں بُجھ گئی یعنی حضرت الاستاذ مولانا محمدانور شاہ الکشمیریؒکے تلمیذِ رشید اورہمارے دیرینہ رفیقِ کار اورساتھی مولانا الشیخ محمدبدر عالم میرٹھی نے گزشتہ ماہ کے آخری ہفتہ میں تین برس کی مسلسل اور شدید علالت ومعذوری کے بعد مدینہ منورہ میں وفات پائی۔ مولانا کے والد ماجد پولیس کے افسرِ اعلیٰ تھے۔ مگران کی نیکی اور دین داری کایہ عالم تھا کہ اس ملازمت کے باوجود انھوں نے بیٹے کوعربی ودینی تعلیم کے لیے سہارنپور بھیجا، وہاں سے فارغ ہو کر مولانا دیوبند آئے اورحضرت الاستاذ کے درسِ بخاری میں شریک ہوکرکئی سال مسلسل سماع کیااور درسی تقریریں قلمبند کیں۔ علاوہ ازیں حضرت شاہ صاحب کی خدمت میں صبح وشام یوں بھی حاضر رہتے اور برابر علمی استفادہ کرتے رہتے تھے۔ اسی زمانہ میں مختلف علوم وفنون کے اسباق آپ کے سپرد ہوگئے۔ مولاناکی استعداد بڑی پختہ اوران کاذوق ہمہ گیرتھا۔منطق، فلسفہ، ادب، حدیث اور فقہ، ان میں سے ہر مضمون کی کتاب اس طرح پڑھاتے تھے کہ گویا وہ ان کا کوئی خاص فن تھا۔۲۸ء میں حضرت شاہ صاحب اپنی جماعت کے ساتھ ڈابھیل گئے تومولانا بھی اس جماعت کے رکن ِرکین تھے۔ وہاں انھوں نے نہایت محنت اور توجہ سے بڑی سے بڑی کتابوں کا درس دیا۔ لیکن حضرت الاستاذسے استفادہ کی تشنگی کم نہیں ہوئی،بلکہ اُس میں روز بروز اضافہ ہوتا اور یہ مس ِ خام کندن بنتا رہا۔ یُوں بھی وہ حضرت الاستاذ کے عاشق تھے۔صورت کے بھی اور سیرت کے بھی! ان سب چیزوں کا مجموعی اثر یہ ہواکہ حضرت الاستاذ کے ہزاروں شاگردوں میں بڑے بڑے نامور علماء وفضلاء بھی ہیں اورمحققین واساتذہ بھی، لیکن خاص فن ِ حدیث میں جوجامعیت اورکمال (مولانا محمدیوسف بنوری کو مستثنیٰ کرکے) مولانا کے حصہ میں آیا وہ کسی...
Current scenario of newer diseases with multiple causes has drawn the attention of the researchers in the field of therapeutics and they are now inclined to identify molecules effective for targeted therapy. Objective: Quinoline (1-azanaphthalene); belongs to heterocyclic aromatic nitrogen compound. Some quinoline-based derivatives are also known for their anti-tumor activity. The study was planned to evaluate the cytotoxic potential of quinoline derivatives. Methods: Berberine; a quinoline compound was made part of study to make structural analogs which were docked against potential target proteins. Cytotoxic profiling of all derivatives was done using MTT cytotoxicity assay. Results: The pharmacoinformatic and structure activity relationship studies of analogs were done. The cytotoxic profiles were elucidated by comparing viability rates of analogs treated hepatic cancerous cell line with untreated hepatic cells and untreated mesenchymal stem cells as standards. Marked cytotoxicity was seen in all molecules at low doses than reported in past studies with relevance to parent compound. Conclusions: The results will be further confirmed through various other cell culture assays targeting different marker proteins, pharmacoinformatics tools and structure activity relationship studies
The purpose of present study was to analyze occupational stress and personality type of academic
managers serving in public sector degree colleges in Punjab. Major objectives of the study were to find
out the relationship between occupational stress and personality types among academic managers of
the higher education institutions, to identify the level of occupational stress among academic managers
of the higher education institutions, to determine the gender differences regarding occupational stress
and personality types. All the 295 government degree colleges in Punjab constituted the population of
the study, out of which 120 were taken as representative sample. Data were collected through
Occupational Stress Inventory–Revised and Myers Briggs type indicator personality. Data were
analyzed by using descriptive statistics such as Mean, Standard deviation, Percentages and Inferential
statistics such as t-test and Pearson Correlation. Analyses of the data lead to the findings.
On the basis of findings major conclusions were drawn which indicated a high level of occupational
stress in females than males. The occupational role that academic managers perform was reported as
the main source of stress. Data revealed that main domain of personality types among both male and
female academic managers were found as extroversion, sensing, thinking and judging. It was also
concluded that there is significant positive correlation between extroversion, sensing, thinking, judging
types of personality and occupational stress whereas significant negative correlation was found
between introversion type of personality with occupational stress.
Based on conclusions it was recommended that steps should be taken to reduce the occupational stress
of academic managers in higher education in order to improve the physical and mental health of
academic manager which will ultimately lead to the development of healthy and calm environment in
higher education institutions consequently enhancing the quality of higher education.