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Development and in Vitro Evaluation of Self Nano Emulsifying Drug Delivery System for Aceclofenac

Thesis Info

Author

Kalsoom Saleem

Supervisor

Muhammad Ijaz

Program

Mphil

Institute

Riphah International University

Institute Type

Private

City

Islamabad

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Page

iii, v, 53 . : ill. ; 30 cm.+ CD

Subject

Medicine & Health

Language

English

Other

A thesis is submitted in partial fulfillment of the requirements for the degree of Master of Philosophy to the Faculty of Pharmaceutical Sciences.; Includes bibliographic references; Thesis (M.Phil.)--Riphah International University, 2019.; English; Call No: 615.19 KAL

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676711200676

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آیاتِ استفہام اور فہم معاملات

اسلامی معاشرے کا قیام اس لیے ضروری ہے تاکہ خیر کے فروغ اور شر کے خاتمے کو یقینی بنایا جا سکے لیکن اس مقصد کے حصول کے لئے معاشرے کے ہر فرد کو اپنا اپنا کردار کرنا ہوگا۔ کیونکہ اسلام انسانیت کی فلاح و بہبود، بقاو ارتقاء کے زریں اصولوں کا امین ہے اور حق کی پاسداری، معاشرے کے اعلیٰ اقدار کا قیام اور انسانی معاشرے میں باہمی حقوق کا احترام اسلامی تعلیمات کی بنیادی روح ہے۔

اللہ تبارک و تعالی انسان کے خالق ہیں اور انسان کی فطرت سے اچھی طرح واقف ہیں۔ اللہ تعالی نے سیدھے راستے کی طرف اپنے بندوں کو بلایا ہے ۔ اور زندگی کے ہر معاملے میں رہنمائی فراہم کی۔

قرآن مجید کا مرکزی موضوع ہونے کے ناطے ، کتاب مقدس میں انسان سے متعلق مختلف پہلوؤں کے بارے میں بات کی گئی ہے ، جس سے انھیں ایک خاص اہمیت حاصل ہے۔ اسلام انسانی اقدار اور خاندانی زندگی کے بارے میں ایک واضح اور قابل تقلید تصور پیش کرتا ہے۔ خاص طور پر ، اسلام کے ذریعہ پیش کردہ انسانیت کا احترام کرنے کا تصور غیرمعمولی ہے اور دوسری قومیں اس سے محروم ہیں۔ اسلام نے سب سے پہلے انسانی نسل اور وقار کی مساوات پر مبنی ایک نظام کی بنیاد رکھی۔ اس کے بعد ہی مذہب اسلام نے انسانوں کو مذہبی ، اخلاقی ، معاشی ، معاشرتی اور سیاسی شعبوں میں لاتعداد حقوق دیئے۔ انسانی حقوق اور آزادی کا اسلامی تصور آفاقی اور عدل پر مبنی ہے ، جس میں وقت اور جگہ کی تاریخی اور جغرافیائی حدود کا کوئی لحاظ نہیں ہے۔ اسلام کا انسانی حقوق کا چارٹر اللہ رب العزت نے عطا کیا ، جو ساری کائنات کا خدا ہے ، اور یہ پیغام اللہ نے آخری نبی حضرت محمد...

Exploring the Objectives of Model Madaris Curriculum: Practical Approach Analysis

Islamic history reveals that Muslim rulers had taken keen interest to establish educational institutions during their rule. To keep going on this legacy of the Muslim rulers, various governments in Pakistan, since its creation, has announced a number of educational policies. Besides suggestions for Islamic education, a concept of Model Madaris at federal level was introduced for the first time during Musharraf’s regime [1999-2008]. Ministry of Religious Affairs (MORA) was made responsible to develop the curriculum for these Madaris from middle to master levels; however, as per constitution the Education Act 1976, it is the responsibility of Curriculum Wing, Ministry of Education to develop the curriculum up to higher secondary level with pre-framed objectives. While at graduate and post graduate level, it is the responsibility of the universities to develop curriculum through their statutory bodies i.e. Board of Studies, Board of Faculty and Academic Council as per guide lines set by the Higher Education Commission of Pakistan. This study is an effort to explore the main objectives of Model Madaris curriculum. Moreover, it will be cross checked with course contents from middle to bachelor levels and policy suggestions will be directed that how these objectives and course contents can be amalgamated in one line.

Prevalence and Management of Meloidogyne Graminicola Golden and Birchfield on Rice Oryza Sativa L.

Meloidogyne graminicola is one of the major pest threatening rice production in the world. Studies to estimate M. graminicola prevalence and incidence were conducted during 2014-2016 in rice fields of Faisalabad and Chiniot districts of central Punjab, Pakistan. Studies revealed variation in prevalence and incidence of M. graminicola at both districts. Maximum prevalence of M. graminicola was observed 22.5% and 27.5% in Chiniot and Faisalabad respectively during the rice growing season of 2016, while, 20% from Chiniot and 25% from Faisalabad during 2015 and minimum prevalence was recorded 17.5% and 20% during 2014 respectively. The severity of nematode attack on the rice roots and infested fields was based on different attributes like galling index, root-knot nematodes (RKN) per root system, RKN per 100ml of soil, stylet bearing nematodes and non-stylet bearing nematodes were recorded with varying degree of infestation at various locations. Meloidogyne graminicola isolates were recovered from soil and root samples. The isolates were identified on the basis of perineal pattern and ITS based sequencing. Eleven alternate host plant species were examined in this study that showed varying degree of M. graminicola infestation. ITS sequencing and phylogenetic analysis of eight isolates indicated that most of the isolates from this study clustered together with isolates of India, Nepal, Vietnam and China. The results indicate that rice is severely attacked by M. graminicola, necessitating the development of appropriate control measures for its management in rice and other crops related to gramineae family. Twelve cultivars of rice and forty eight advance lines showed different reaction against M. graminicola i.e. tolerant, partially tolerant, susceptible and highly susceptible. Response of forty eight advance lines and 12 cultivars against root knot nematode M. graminicola were observed. Among twelve cultivars Basmati Pak, Super Basmati, PK-386 and Sheen Basmati showed susceptible reaction while Basmati 385 showed highly susceptible reaction and rest seven varieties were moderately susceptible (PS-2, Kashmir basmati, IR-24) and partial tolerant (Basmati-2000, NIAB IR-9, Basmati-198, Basmati 515 ). Among 48 advance lines ten lines showed tolerant reaction, fourteen lines showed partial tolerant, fifteen advance lines showed moderately susceptible and eight advance lines showed susceptible response. Nematicidal potential of five synthetic chemicals i.e., Furadan Rugby, Match, Polo and Matanza were tested against M. graminicola at their standard (S), half (S/2) and double dose (2S) levels. Results of in vitro study disclosed that all chemicals except Polo significantly inhibited egg hatching and J2s mortality of M. graminicola. Furadan, Rugby, Match and Matanza were found effective to inhibit 88.4, 86.3, 89.7 and 81.0% egg hatching, respectively as compare to control while Polo inhibited only 32% egg hatching. Moreover, Furadan and Rugby significantly inhibited the invasion and development of nematodes on rice compared to control. In field study, all chemicals were applied either as root dip or soil application. Match, Furadan and Matanza treated plants observed significantly lower number of eggs and J2s against control. Both applications methods were effective, but soil application was the best. All the chemicals applied either as root dip or soil application improved plant height, shoot weight, grain weight by inhibiting nematode reproduction i.e., gall formation, development of adult females, eggs and nematode population in soil except Rugby that caused phytotoxic effects on plants. All the chemicals were found more effective at their standard dose than double or half dose. In conclusion, soil application of all tested chemicals in this study except Rugby seemed viable option for chemicall control of M. graminicola in rice fields of Pakistan.