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In-Silico and Pharmacological Evaluation of Papaverine Derivatives

Thesis Info

Author

Hamida Shahnawaz

Supervisor

Madiha Kanwal

Program

Mphil

Institute

Riphah International University

Institute Type

Private

City

Islamabad

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Page

vii, 38 . : ill., Col. ; 30 cm.+CD

Subject

Medicine & Health

Language

English

Other

A thesis is submitted in partial fulfillment of the requirements for the degree of Master of Philosophy to the Faculty of Pharmaceutical Sciences.; Includes bibliographic references; Thesis (M.Phil.)--Riphah International University, 2019; English; Call No: 615.19 HAM

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676711260677

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اختر لایمان کی نظم ’’مسجد ‘‘کا تنقیدی جائزہ

منظر نگاری:
اختر الایمان نے جو منظر کشی کی ہے وہ المناک ہوتے ہوئے بھی دل فریب ہے۔اس نظم میں شاعر نے کہیں دور اشارہ کر کے ایک مسجد کی نشاندہی کی ہے۔ برگدی گھنی چھاؤں میں ماضی اور حال گناہگار نمازی کی طرح رات کی تاریک کفن کے نیچے اپنے اعمال پر آہ و زاری کرتے ہیں۔ اسی برگد کی چھاؤں میں ایک ویران سی مسجد ہے جس کا ٹوٹا ہوا کلس پاس بہتی ہوئی ندی کو تکا کرتا ہے۔ اسی مسجد کی ٹوٹی ہوئی دیوار پر کوئی الّو (چنڈول) کوئی پھیکا سا گیت چھیڑ دیا کرتا ہے۔
دور برگد کی گھنی چھاؤں میں خاموش و ملول
جس جگہ رات کے تاریک کفن کے نیچے
ماضی و حال گنہ گار نمازی کی طرح
اپنے اعمال پہ رو لیتے ہیں چپکے چپکے
تشبیہات کا استعمال:
اس نظم میں برگدی گھنی چھاؤں ماضی سے مشابہ ہے۔ رات کو تاریک کفن سے موسوم کیا گیا ہے۔ ماضی و حال کا خاموش و ملول ہونا، شکستہ کلس کا ندی کو تکنا ، بے بسی، مایوسی اورپاسیت کو واضح کرتا ہے۔ چنڈول ایک منحوس پرندہ مانا جاتا ہے اور پھر اس الّو کا کوئی پھیکا سا گیت چھیڑنا یہ بھی توجہ طلب ہے۔ شاعر نے نظم میں ڈوبتے سورج کے لئے ’ سورج کے وداعی انفاس‘کا استعمال کیاہے جس سے اس بات کا اندازہ ہوتا ہے کہ قدرت نے بھی اس مسجد کی طرف منہ موڑ لیا ہے۔
ایک ویران سی مسجد کا شکستہ سا کلس
پاس بہتی ہوئی ندی کو تکا کرتا ہے
اور ٹوٹی ہوئی دیوار پہ چنڈول کبھی
گیت پھیکا سا کوئی چھیڑ دیا کرتا ہے
تجسیم نگاری:
نظم میں جوسب سے بڑی فن کاری دکھائی گئی ہے وہ یہ ہے کہ اس دعاؤں کوسننے والا کوئی شخص نہیں بلکہ ان دعاؤں کے گواہ شام و سحر ہیں...

اسلامی تعلیمات کی روشنی میں مروجہ پاکستانی ٹریفک قوانین کی پاسداری کی اہمیت

Islam is a comprehensive code of conduct which encompasses to each sphere of human life. This also owns and endorses those manmade rules which serve the cause of humanity and not entering to its fundamentals. Adherence to Pakistani Traffic rules also falls under the preview of the same doctrine. It is very pertinent to note here, that the same traffic rules such as fastening of seat built, proper use of indicators, speed control etc. Have been devised to ensure the safety which starts from a pedestrian and ends up to a rider of any vehicle class. Any violation of traffic rules is an indirect breech of divine discipline imposed by Allah the Almighty. If the violation costs any damage, injury or fatal accident, this will directly be dealt under the principles set by Islam. This study aims at highlighting the significance of adherence to traffic rules which is directly linked to the ground safety. This ultimately serves the main purpose of saving any precious human life. If the same is ensured, no doubt the purpose of the holy verse would be fulfilled

Spatio-Temporal Wave Packet Dynamics in Fermi-Ulam Accelerator

The idea of wave packet, that clarified many conceptual difficulties, has more recently been revisited to address interferometric and dynamical issues. Present work focuses on the spatio-temporal dynamics of the quantum wave packets in the Fermi-Ulam Accelerator Model. The specific system considered here is a one-dimensional box under periodic oscillations at one boundary. Such a seemingly simple system can be mapped to non-trivial problems like BEC trapped in an oscillating cavity or dynamics of atomic wave packet in different potential in presence or absence of gravitational field. The system is shown to display rich dynamical features including transitions from regular to stochastic and further to chaotic domain in classical phase space. We have obtained the approximated eigen-value solutions of the problem through time dependent Schrodinger’s equation under rescaling transformations that effectively replace moving boundary with a static one. Consequently the running time becomes a nonlinear function of the continuously changing boundary. Based on these solutions, revivals or the resurrection of the original wave packet, in the driven and un-driven Fermi-Ulam model are presented. Such revivals correspond to the constructive interference whereas the wave packet’s collapse owes to destructive interference. Furthermore, interplay of constructive and destructive interferences also readily mimics the fractional revivals. It is further demonstrated that initial position and momentum play a highly crucial role in the emergent revival and fractional revival patterns. It is shown that the symmetries exhibited by such structures in un-driven systems are usually lost under driven conditions and the revival/fractional revival times can only be predicted through a transcendental equation whose solution mainly depends on the strength of the external driving force. In present thesis we have proposed a comprehensive mathematical technique to calculate these hitherto unpredictable times. In addition, a graphical method is also suggested to observe these asymmetric revival/fractional revival times. This apparent asymmetry, do display an overall periodicity over a comparatively long span covering many times of revivals. It is found that whenever the ratio between the period of wall oscillation and quantum revival time `α/β'' is a rational number then the revivals time shows a periodicity after β viinumber of revival times over α wall oscillation. Standard tools of autocorrelation and quantum carpets, a consequence of quantum interference, have been employed for visual manifestation of these revivals. These carpets amply demonstrate the explicit asymmetric shifting of revival times for the driven case. These micro changes exhibited in quantum carpet morphologies consequently yield amended phase velocities associated with the canals and ridges in the driven framework. Furthermore, to grasp the quantum phase space dynamics in its entirety, we have also utilized the more sophisticated techniques of the Wigner function and information entropy. It is demonstrated mathematically that revivals not apparent via autocorrelation become prominent in the Wigner phase space description along with the appearance of smooth mini wave packets in the fractional revivals. These interference patterns emerge due to the state vector formed through the linear combination of Gaussians with different positions and momenta having pure Gaussian as well as oscillatory terms. Moreover, the information entropy, like the Wigner function also predicts the revivals when and where they happen. Thus a rich pattern of fractional revivals, including some altogether new ones, are observed through this tool in both driven and un-driven situations. Finally we have elucidated various scenarios including cold atoms in magneto-optical traps where such a system can be experimentally realized along with the suggestions for future work in this specific domain.