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In-Vitro Pharmacological Evaluation and Docking Studies of Heterocyclic Nucleosides Novel Derivatives

Thesis Info

Author

Azar Abbas

Supervisor

Fawad Ali

Program

MS

Institute

Riphah International University

Institute Type

Private

City

Islamabad

Country

Pakistan

Thesis Completing Year

2016

Thesis Completion Status

Completed

Page

xiv, 65 . : ill.; 30 cm.+CD

Subject

Medicine & Health

Language

English

Other

A thesis submitted in partial fulfillment of the requirements for the degree of Master of philosophy; Includes bibliographic references; Thesis (MS)--Riphah International University, 2016; English; Call No: 615.1 AZA

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676711661569

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خاندانی پس منظر
ڈاکٹر شہزاد احمد کا خاندان رواداری ، تقویٰ ، طہارت اور اکل حلال کے حصول کے لیے بہت مشہور ہے۔ آبائواجداد کا تعلق حبیب گنج علی گڑھ (انڈیا) سے ہے۔ یہ خاندان پٹھانوں کے قبیلے ’’یوسف زئی‘‘ سے تعلق رکھتا ہے جب کہ ڈاکٹر شہزاد احمد کی والدہ محترمہ کی نسبت ’’آفریدی‘‘ قبیلے سے ہے۔ والد کے خاندان کے مورثِ اعلیٰ حافظ نتھے خان تھے جو پابندِ شریعت اور صوم وصلوٰۃ کے دل دادا تھے انھیں عشقِ رسول صلی اللہ علیہ و آلہٖ وسلم وراثت میں ملا تھا۔ صحیح العقیدہ مسلک حق اہل سنت والجماعت کے پیروکار تھے۔ تمامی انبیائے کرام علیہم السلام ، اہل بیت اطہارؓ، صحابہ کرامؓ، اولیائے کاملینؒ بالخصوص حضرت پیران پیر ، روشن ضمیر ، غوث الاعظم دستگیر رحمتہ اللہ علیہ اور حضرت خواجہ خواجگان، سلطان الہند ، حضور غریب نواز رحمتہ اللہ علیہ کے عقیدت مندوں میں شامل تھے۔
اس خاندان کے مورثِ اعلیٰ قبلہ حافظ صاحب کے چار فرزند ارجمند تولد ہوئے: اصغر خان ، اکبر خان ، صفدر خان، اشرف خان۔ان سطور میں صرف ڈاکٹر شہزاد احمد کے دادا صفدر خان کا ذکر خیر مقصود ہے جو حافظ صاحب کے تیسرے نمبر کے صاحبزادے ہیں ۔ انھیں اللہ تعالیٰ نے سات صاحبزادوں...

POLA PEMBINAAN KEAGAMAAN PESERTA DIDIK MELALUI PROGRAM PALU KANA MAPANDE (PKM) DI KOTA PALU

This study discusses the pattern of religious guidance of learners through PKM program, learning interests, and the implications of religious guidance through PKM program in Elementary School Inpres Perumnas Palu Barat. This research is a qualitative descriptive research based on phenomenological approach, that is describing various events and its relation to learners in certain situations. Data collection is done through observation, interview, and documentation. The results showed that the pattern of religious guidance through PKM program in SDN Gugus IV (SD Inpres Perumnas) was greeted enthusiastically by the students. However, the interest of learners in following religious coaching is different, some are very enthusiastic, but some of them not enthusiastic. The implication of religious guidance through PKM program can correct and improve the ability of learners in reading and writing verses of Al Quran. They can also actualize memorization materials, daily prayers, and understand the procedures of worship in daily life.

3D Simulations of Low-Mass Proto-Stellar Disks With Certain Initial Conditions Using Smoothed Particle Hydro Dynamics

Results of the numerical study on the initial formation stages of low-mass protostellar systems leading to single, binary, triplet, and quadruple protostar systems formation are reported here. In addition to these various types of protostellar objects we also investigate the overall structure formation that takes place within collapsing molecular cores that yield during the course of evolution the spiral structure formation, ring formation, and bar formation under various initial conditions chosen for a rotating solar mass cloud of molecular hydrogen to mimic the states prevailing in star formation regions in our Milky Way galaxy. There have been three key parameters belonging to the initial star forming conditions whose effects on the overall outcome of protostallar systems have been examined. These parameters are the initial thermal state of the prestellar core, the amplitude of azimuthal density perturbation introduced in initially uniform density state of the core, and the impact of the critical density which governs the transition from isothermal to adiabatic thermodynamic behavior of the collapsing core. For protostellar binaries, the separation is determined as a function of the initial thermal state of the core by varying its initial temperature. For this purpose a slightly modified version of the Burkert and Bodenheimer collapse test is taken into consideration. We find that the result is fairly sensitive to both the initial thermal state of the cloud and the initial azimuthal density perturbation’s amplitude A. For A=10 %, variations of only 1 unit Kelvin below 10 K causes a change of up to 100 AU in protobinary separation, while for this small amplitude of perturbation the initial temperatures above 10 K result a single low-mass fragment, instead of a binary, that does not reach even near to the protostellar densities. However, protostellar binaries, do appear if the amplitude of perturbation is enhanced from 10 % to 25 %. A star forming hydrogen gas is normally considered to be initially at 10 K. For structural formation study, we have explored that an oscillation around this normally considered value can be influential in determining the fate of a collapsing gas as it evolves in its structural properties that may lead to formation of proto-stars. We examined the initial range of temperature of star forming gas between 8 K to 12 K and tried to compare the emerging physical properties within the early phase of formation of protostellar system. According to our findings the spiral structures are likely to appear in a strongly perturbed molecular cores that commence their phase of collapse from temperatures lesser than 10 K. However, cores with initial temperatures more than 10 K potentially develop, instead of spiral, a ring structure which afterwards experiences the clumps formation. It is possible to observe a transition from spiral to ring instability at a typical initial core temperature of 10 K. Similarly, while investigating the effects of critical density variations on the evolution of protostellar systems, we find that the critical density affects the structural evolution of the envelope of gas, also the dimension of emerging rotating disk structures during collapse too get affected as well as the number of fragments appearing from the concluding fragmentation of the disks. It is suggested that this mechanism has the potential to give birth to young protostellar objects that may eventually constitute systems of bound multiple protostars. The entire numerical experiment is conducted by using 250025 SPH particles to construct virtually the geometry of each molecular core investigated here.