درد کا حد سے گزرنا ہے دوا ہو جانا
نحمدہ ونصلی علی رسولہ الکریم امّا بعد فاعوذ بااللہ من الشیطن الرجیم
بسم اللہ الرحمن الرحیم
معزز اسا تذہ کرام اور میرے ہم مکتب ساتھیو!السلام علیکم! آج مجھے جس موضوع پر گفتگو کرنی ہے وہ ہے:’’درد کا حد سے گزرنا ہے دوا ہو جانا ‘‘
جنابِ صدر!
دکھ درد، تکلیف ہم معنی الفاظ ہیں، زندگی میں ہر شخص کوکسی نہ کسی موقع پر رنج وغم اور دکھ و تکلیف سے واسطہ پڑتا ہے خوشیاں روٹھ جاتی ہیں، رنج و الم کے بادل گھٹائیں بن کر برسنا شروع ہو جاتے ہیں گھر کے آنگن میں نوید ومسرت کی چاندنی بکھیرنے والا قمر گہنا جاتا ہے۔
صدرِ ذی وقار!
زندگی کے نشیب وفراز سے انسان ہمکنارر ہتا ہے۔ افراط و تفریط کا سلسلہ شروع رہتا ہے، کامیاب انسان وہ ہے جوایسے حالات میں مستقل مزاج رہتا ہے ان بوقلمونیوں سے اس کے پائے استقلال میں لغزش نہیں آتی اور یوں اس کی زندگی کی گاڑی رواں دواں رہتی ہے۔بقول غالبؔ
رنج سے خوگر ہوا انساں تو مٹ جاتا ہے رنج
مشکلیں اتنی پڑیں مجھ پر کہ آساں ہو گئیں
صدرِ محترم!
جب کوئی چیز حد سے بڑھ جاتی ہے، اپنی انتہا کو پہنچ جاتی ہے تو اس کا وجود عنقا ہو جاتاہے اس کی حیثیت بدل جاتی ہے اس کے نفع نقصان کا تصور تبدیل ہو جاتا ہے۔ اس کے مضر اثرات مصلح ہو جاتے ہیں اس میں یکسر تبدیلی آجاتی ہے اور ایّام کے ساتھ ساتھ وہ قصہ پارینہ بن جاتی ہے۔
محترم سامعین!
رات اپنی انتہا کو پہنچتی ہے تو بادِ نسیم صبح کے حیات بخش جھونکوں سے آشنا ہے۔ دن اپنی بلندیوں کومس کرتا ہے تو قمر کی برووت بھری چاندنی قلب و ذہن کی طراوت کا باعث بنتی...
This paper presents the usage of Information Communication Technology (ICT) tools in Islamabad High Court (IHC) and determine the applications of ICT tools in the court. ICT plays vital role in the court processes. It has been adopted all over the world to enhance the performance of judiciary. The analyses are based on the primary collected data through survey questionnaire from judges, lawyers, clients, IT operators and administrative staff. The findings of the study revealed that ICT tools have been uses, particularly, basic IT tools such as computers etc. Are most commonly uses in the courts, however, it needs to use advance tools. Most of the respondents agreed that overall ICT tools have been adopted in the court. It is suggested for the IHC court to increase the judge’s ratio in the courts and bring judicial reforms in the system. The new findings and recommendations would be helpful for IHC.
The work reported here deals with the bio-assay guided isolation of secondary metabolites from Cestrum nocturnum (leaves) and Cestrum diurnum (leaves and berries). First part of the dissertation deals with the biological activities of different parts of the selected plants while second part describes the purification and characterization of the isolated constituents. Shade dried plant material was extracted with methanol. The concentrated methanolic extract was fractionated with n-hexane, chloroform, ethyl acetate and iso-butanol and extractive values determined. All the collected extracts were screened for anti-bacterial, anti-fungal, anti-oxidant and anti-leishmanial activities. The anti-oxidant experiment was also conducted with all the parts. Crude extract of aerial part of C. nocturnum displayed 57 % antioxidant activity while one of its isolated fractions (ethyl acetate) displayed a maximum of 67 % antioxidant activity. Similarly, the crude extract of aerial parts of CD i.e., aerial part without fruit, green fruit, ripe fruit, exhibited 86, 81 and 90 % antioxidant activities respectively. The hexane fraction of CD green fruit showed higher antioxidant potential (87 %) than its crude methanolic extract. Due to our interest in saponins for further studies, they were selectively isolated and processed in the same way for antioxidant activities in crude form from both the plants. The highest antioxidant activity was found with the CD ripe fruit CS extract (90 %) while the least one was with both the aerial parts of the two plants (approx. 80 %). The results obtained with nine microbial strains were moderate. S. typhii was the most resistant strain. On the average gram positive bacteria showed good zone of inhibition with Cestrum diurnum. Gram negative strains showed good results mostly with Cestrum nocturnum. The crude saponins extracts of berries were the most active giving zone of inhibition in the range of 8.5-15mm. Incredible anti-leishmanial activities are being reported for the selected plants. All the plant extracts exhibited hundred percent inhibition of the leishmania parasite. Second part of the thesis deals with the isolation and purification of the secondary metabolites of C. nocturnum and C. diurnum. Hum-V isolated from C. nocturnum was characterised using different spectroscopic techniques as (25R)- spirost-5ene-2,3-diol, [2α, 3β] 3-O-{β-Dglucopyranosyl (1→4)-β-D-glucopyranosyl (1→2)-β-D-glucopyranosyl{(1→4)-β-Dxylopyranosyl] (1→4)-β-D-galactopyranoside). It was reported as nocturnoside A. Another reported compound was also purified and characterized as karatavoiside A, spirost-5-ene-2,3-diol [2α, 3β,25R], 3-O- [β-D-glucopyranosyl(1→2)] {-β-Dxylopyranosyl( 1→3)-β-D-glucopyranosyl(1→4)}-β-D-galactopyranoside. A new compound isolated from the same specie, elucidated as 3-O-β-D-xylopyranoside-olean- 12-en-28-oic acid-28-O-β-arabinopyranosyl-(1-3)-β-D-galactopyranosyl-(1-2)- β-Lglucopyranosyl-( 1-4)- β-L-glgucopyranosyl ester.