عروج آدم ِخاکی سے ا نجم سہمے جاتے ہیں
نحمدہ ونصلی علی رسولہ الکریم امّا بعد فاعوذ بااللہ من الشیطن الرجیم
بسم اللہ الرحمن الرحیم
معزز اسا تذہ کرام اور میرے ہم مکتب شاہینو!آج مجھے جس موضوع پر اظہار خیال کرن ہے وہ ہے:’’عروج آدم خاکی سے انجم سہمے جاتے ہیں‘‘
جنابِ صدر!
انسان کو اللہ تعالیٰ نے اعلیٰ مقام عطا فرمایا ہے، اس کو کلامِ مجید میں اشرف المخلوقات کا تاج پہنایا ہے، اس کی عظمت کو فرشتوں سے منوایا ہے، اس کو مسجودِ ملائکہ بنایا ہے، اس کے شرف سے دیگر مخلوقات کو آگاہ فرمایا ہے۔
فرشتے سے بہتر ہے انسان بننا
مگر اس میں پڑتی ہے محنت زیادہ
صدرِذی وقار!
انسان جب اپنی تخلیق کا مقصد پہچان لے، اپنے وجود کے بارے میں آگاہی حاصل کر لے، اپنی حیات کوصحیح خطوط پر گزارنے کا سلیقہ حاصل کرلے، اپنے لمحات زیست سودمند مواقع کی تلاش میں صرف کر دے، اپنے حواسِ خمسہ کا صحیح استعمال کرنا سیکھ لے تو اس کو اپنی منزل آسمانوں پر نظر آنی شروع ہو جاتی ہے۔
عقابی روح جب بیدار ہوتی ہے جوانوں میں
نظر آتی ہے ان کو اپنی منزل آسمانوں میں
صدرِمحترم!
اس آدم خاکی نے جب سرحدوں کا رخ کیا تو دشمن لرزہ براندام ہو گئے ، دشمن کو قہر آلود نظروں سے دیکھا تو ان کے رونگٹے کھڑے ہو گئے ، اعداء پر ضربِ کلیمی لگائی تو فضاء گونج اُٹھی، اس نے دشمنوں کی زندگی اجیرن کر دی ، اس کی نسلوں تک مار کرنے والے تصورات پیش کیے، دشمنِ اسلام کو بتایا کہ خدا اور اس کے رسولﷺ کے پیروکارکبھی گھبراتے نہیں۔
دو نیم ان کی ٹھوکر سے صحرا و دریا
سمٹ کر پہاڑ ان کی ہیبت سے رائی
جنابِ صدر!
انسان جب کھیتوں ، کھلیانوں میں پہنچتا ہے تو انہیں...
Islam is a complete code of life and it provides complete guidance in every field of life. Islamic law provides protection to the human wisdom, race and respect. Spiritual purity, sacred heart and environmental cleanliness, is one of the important persistence of Islamic sharia. Every act which leads us towards ignorance, contradiction, ambiguity and vulgarity is prohibiting in human societies. Zina has destroyed the spiritual values of individuals, families, societies and even nations. This ruthless deed is not only prohibited and sentenced in Islam, but also rather detested by other heavenly religions as well. Without discrimination of any religion, many scholars considered this hated act as the source of unrest and anarchy. Physically, ethically, medically, socially and even religiously zina has infinite hindrances in the society. Islam has provided various teachings and precautions to shun from this major sin for the protection of greatness and superiority of humanity. One of the important teachings is punishment for committing this sin, which is known as “Hadd” in Islamic sharia. In the current book, the punishments of married and unmarried (Fornicator) zani have been described in the light of Sunnah and Quran. The important purpose of Qisas and Hadd is the correction of societies, protection of life, respect and wealth, not the humiliation of people. To punish the criminals is the source of rectification for others.
Present research work was planned for the formulation of cardioprotective nanosuspensions of four indigenous medicinal plants with improved bioavailability and better therapeutic efficacy. Ongoing research was divided into four different phases. First phase of the study was comprised of formulation and optimization of formulative parameters for the preparation of stable nanosuspensions by using CCD design of RSM. Characterization (ZP, SEM, AFM and FTIR) and stability studies of optimized nanosuspensions was the second phase of the study. In third phase of study, in-vitro dissolution testing and in-vivo pharmacokinetic profile of selected nanoformulations was determined. In fourth phase, different in-vitro and in-vivo bioactivities and toxicity studies of optimized nanosuspensions were evaluated with reference to the respective coarse plant suspensions. Results of stabilizer screening demonstrated that SLS was the best stabilizer for the formulation of A. cepa and C. oxyacantha nanosuspensions. HPMC was the selected stabilizer for P. nigrum and P-80 was chosen for the formulation of T. arjuna nanosuspensions. Among the optimized nanosuspensions, minimum particle size with appropriate PDI value was possessed by T. arjuna (79.1nm, 0.244) followed by C. oxyacantha (121.3nm, 0.241), P. nigrum (172.9nm, 0.328) and A. cepa (275.5nm, 0.415) nanosuspension. Results of zeta potential studies confirmed the stability of the optimized nanosuspensions. Results of AFM and SEM illustrated that nanosuspensions were in nanometer range with varied particle size and morphology. FT-IR studies indicated slight interaction between herbal extracts and stabilizers. Moreover, optimized nanosuspensions of all the four medicinal plants showed better stability at refrigerated conditions. Dissolution and pharmacokinetic studies demonstrated improved results for nanosuspensions as compared to coarse suspensions of the respective plant extracts. In-vitro (antioxidant, antimicrobial, hemolytic, thrombolytic) and in-vivo (cardioprotective) bioactivities also revealed better therapeutic efficacy of nanosuspensions over coarse suspensions. Results of toxicity studies confirmed the non-toxic nature of formulated nanosuspensions. From the present results it was concluded that nanosuspensions of the selected herbal extracts can be used as a better alternative to treat cardiovascular diseases with improved therapeutic efficacy as compared to their conventional coarse suspensions.