مولانا عبدالسمیع
گزشتہ ماہ کاالم ناک سانحہ دارالعلوم دیوبند کے قدیم تر استاذ حضرت مولانا عبدالسمیع صاحب ؒ کی وفات ہے۔مولانا مرحوم کئی ماہ سے علالت کے امتداد واشتداد کی تکلیفیں اٹھا رہے تھے، بالآخر ۱۰/صفر المظفرکو ہمیشہ کے لیے اس جہان فانی سے رخصت ہوگئے۔
مرحوم حضرت مولانا میاں سید اصغر حسین صاحبؒ کے مخصوص ہم سبقوں میں تھے اوربزرگوں کی خوبیوں اورخصوصیتوں کے جامع، بڑے با وضع، بڑے سادہ مزاج اوردارالعلوم کے اساتذہ میں بعض اوصاف کے لحاظ سے بے عدیل و بے مثیل۔ پیرانہ سالی اورغیر معمولی نقاہت کے باوجود جب درس دیتے تھے تو معلوم ہوتا تھا کوئی تازہ دم اور بلندآواز مدرس پورے شوق و انہماک کے ساتھ طلبہ سے مصروف تخاطب ہے۔ مولانا کا طرزتعلیم عام فہم بھی تھا اوردل پذیر بھی، پڑھاتے پڑھاتے بہت سی کتابوں کے حافظ ہوگئے تھے۔اُن کے تلامذہ میں آج بڑے بڑے مدرس بھی ہیں اورباکمال مصنف اورانشاء پرداز بھی۔ ندوۃ المصنفین کے تقریباً تمام بڑے بڑے رفقاء کوآپ سے شرف تلمذ حاصل ہے۔اﷲ تعالیٰ مرحوم کے مراتب بلند فرمائے۔ہمیں اس حادثۂ عظیم میں مولانا مرحوم کے اکلوتے صاحبزادے مولوی عبدالاحد صاحب مدرس دارالعلوم دیوبند سے دلی ہمدردری ہے اورہم اُن کے شریک غم ہیں۔ امید ہے مولوی صاحب موصوف اپنے والد کے صحیح قائم مقام ثابت ہوں گے۔ [فروری ۱۹۴۷ء]
Firstly, I would like to welcome all the readers, authors, editorial team and management of Pakistan Biomedical Journal (PBMJ) to this new journal in Biomedical Sciences. It is an intenational peer-reviewed, open-access journal that merges the basic and clinical research for the better outcome in terms of diagnosis and therapeutics. This approach will update and upgrade the existing knowledge among the researchers and clinicians, regarding the patient care and practice as well as understanding of underlying mechanisms of diseases. The ultimate beneficiary is patient and community as a whole. PBMJ is led by an outstanding Editorial Board comprising of national and international members with multidisciplinary research background. Our goal is to promote the basic and clinical research, health and disease perspectives. We receive original studies, review articles, case reports, systemetic reviews on medical, biomedical, basic and therapeutic research. We welcome scientific contributions from all over the world. It is the need and demand of the recent world scenario to focus on biomedical research. In the current world, basic and medical science cannot be considered as two separate and independent entities. There should be coherent efforts to unveil the basic understandings of pathologies at physiological, cellular and molecular level. Furthermore, the therapeutic strategies should also be explored on regional and global levels, by keeping in mind the different genetic makeups and considering the individual identities. It leads to the field of ‘personalized medicine’. There are many other recent therapeutic regimens such as regenerative medicine, exosomes, gene silencing and gene editing technologies. The world has also advanced in diagnostic modalities. Much focus has been emphasized on rapidness, accuracy and cost-effectiveness of these techniques. Imaging, scanning, histopathological, biochemical and hematological techniques have been much advanced than before. World has been changing rapidly in medical profession. Hence, it is important to be aware of these advancements worldwide and also to share the health related researches at local level. We hope this new journal will be a good addition in this perspective of sharing the recent knowledge, advancements and create awareness among masses.
Alcohols and cyclic alkanes oxidation, in an environment friendly protocol, was carried out in a typical batch reactor. These reactions were carried out in solvent free conditions and/or in eco-friendly solvents using molecular oxygen as the only oxidant and ZrO2 and/or ZrO2 supported noble metals (Pt, Pd) as catalysts. The influence of different reaction parameters (speed of agitation, reaction time, and temperature), catalyst parameters (calcination temperature and loading), and oxygen partial pressure on the catalyst performance was studied. Different modern techniques such as (FT-IR, XRD, SEM, EDX, surface and pores size analyzer and particle size analyzer) were used for the characterization of catalyst. ZrO2 calcined at 1223 K was found to be more active as a single catalyst than the one calcined at 723 K for alcohol oxidation to the corresponding carbonyl products under solvent free conditions and in ecofriendly solvent as well. Platinum supported on zirconia was highly active and selective for oxidation of benzyl alcohol to benzaldehyde in n- heptane, and toluene to benzoic acid in both solvent free conditions and in aqueous medium. Similarly, zirconia supported Pt or Pd catalysts were tested for cyclohexane oxidation in solvent free conditions and for phenol oxidation in aqueous medium. Both catalysts have shown magnificent catalytic activity. Bismuth was added as a promoter to these catalysts. Bismuth promoted Pt/ZrO2 has shown outstanding catalytic performance. These catalysts are insoluble in the reaction mixture and can be easily separated by simple filtration and reused. Typical batch reactor’s kinetic data were obtained and fitted to the classical Langmuir–Hinshelwood, Mars–van Krevelen and as well as to the Eley-Rideal model of heterogeneously catalyzed reactions. In alcohol oxidation reactions the Langmuir-Hinshelwood model was found to give a better fit. The rate-determining step was proposed to involve direct interaction of an adsorbed oxidizing species with the adsorbed reactant or an intermediate product of the reactant. While in toluene oxidation the Eley-Rideal model was found to give a better fit. Eley-Rideal mechanism envisages reaction between adsorbed oxygen with hydrocarbon molecules from the fluid phase. The calculated apparent activation energy and agitation effect have shown the absence of mass transfer effect.