”اور حُسن بھی ہا ر گیا“
سیمیں کرن
کچھ روز سے میں اِک عجیب سے مخمصے سے دو چار ہوں۔ با ت کرتے کرتے کہیں کھو جا تی ہوں۔ میری حا ضر جوا بی و شگفتہ بیا نی جیسے مفقود ہو کررہ گئی ہے۔ اِک عجیب سی پز مر دگی سی چھائی ہو ئی ہے یوں کچھ کھو گیا ہو جو دھو نڈنے پر بھی مل کر نہ دے رہا ہو۔ اِک بے چینی نے میرے و جود کا احاطہ کر رکھا ہے۔ میں نا قا بلِ بیان اذ یت میں ہوں شکست و ریخت کے عمل سے دو چا ر ہوں۔ در اصل ہُوا یوں کہ ___مگر نہیں یوں آپ سمجھ نہیں پائیں گے پہلے میرا تعا رف ضروری ہے۔ میں ایک پینتیس چا لیس سا لہ نو جوا ن خا تون ہوں۔ پینتیس چا لیس سا لہ اورنو جوا ن۔ میرے اِس متضا د بیا ن پر یقینا ہنس رہے ہوں گے۔ آپ اپنی ہنسی میں حق بجا نب ہیں اور اپنے بیا ن میں مَیں بھی غلط نہیں۔ در اصل آپ نے مجھے دیکھا نہیں اگر دیکھ لیتے تو یقینا میرے بیا ن کی صحت پر ایما ن لے آتے۔ آپ اسے میری خو ش فہمی سمجھئے یا مجھے احساسِ بر تری سے ما ری ہو ئی حُسن کے زعم میں گُم کو ئی مغرور حسینہ مگر سچ یہی ہے کہ میں خود شنا س ہوں۔ میں جا نتی ہوں کہ میں اُن چند خوا تین میں سے ہُوں جن کے حُسن و جوا نی پر وقت جیسے آکر ٹھہر سا جا تا ہے اوراس صو رتِ حا ل سے میں اِ ک طویل مدت سے لطف اندوز ہو رہی ہوں۔ مجھے دیکھ کر لوگ پو چھتے ہیں:" Are you miss or mrs"اور جب...
Background: For organizations, conducting work in a safe environment has become mandatory under the provisions and guidelines provided by international and local laws. Occupational health and safety (OHS) standards have become a requisite in almost every industry these days; however, many organizations in developing countries are negligent at adhering to the safety measures, and there is also an absence of proper monitoring. Objective: Our objective was to determine the occupational health and safety standards that are prevailing in the food manufacturing sector of Pakistan. For this, we approached several food manufacturing companies and conducted interviews with quality assurance managers and health and safety executives to evaluate and analyze the workplace conditions to understand their OHS practices. Methods: We conducted 7 interviews with quality assurance managers in the food manufacturing and services companies of Pakistan. The interview guide was used for eliciting responses and a coding method was used to arrive at the themes of the data gathered. Results: The interviews conducted with quality assurance managers and those working to ensure that safety measures are practiced in their company, showed that the export-oriented food manufacturing companies in Pakistan are following OHS standards, as it has become a necessity, with numerous benefits such as ensuring worker safety, maintaining company reputation. However, the extent to which these measures are implemented and strictly followed varies, as there are certain issues that arise when companies try to follow and implement OHS practices The problems vary from company to company however, most of them relate to worker adaptability, costs, and training needs. OHS situation in local firms is concerning. Most of them do not have HSE officers, not the concept of toolbox talk, no preventive and safety measures. These poor practices make the situation unsafe, which lead to fatalities Conclusion: By establishing a national framework for policies and legislations as per the conventions of ILO for a better workplace environment along with proper law enforcement improvement in occupational health and safety domain can be achieved.
Diabetes mellitus is a metabolic disorder having serious consequences on health and is becoming the 3rd most fatal disease worldwide. The current study was designed to prepare, characterize, standardize and explore the antidiabetic potential of a polyherbal formulation comprising aqueous extracts of Momordica charantia,Syzygium cumini, Acacia nilotica, Elettaria cardamomum, Cicer arietinum L, Foeniculum Vulgare and Gymnema sylvestre. Hyperglycemia was induced by alloxan monohydrate. After induction of diabetes polyherbal formulation was administered in graded doses 200 mg/kg, 400 mg/kg & 600 mg/kg to treated groups I, II and III respectively.Prior to start of In-vivo trial, polyherbal formulation was standardized by performing phytochemical, mineral and proximate analysis. Polyherbal formulation was found to be rich in phytoconstituents and minerals with antihyperglycemic and antioxidant potential. Proximate/physicochemical analysis further confirmed the nutritional value of formulation due to the presence of crude fat, crude fiber, crude protein and carbohydrate contents in formulation. Antihyperglycemic potential of polyherbal formulation was determined through biochemical, histopathological and oxidative stress analysis. Results of the study have revealed that polyherbal formulation significantly reversed the alloxan induced hyperglycemia in rat models by improving the biochemical and oxidative stress parameters in dose dependent manner. Highest dose of polyherbal formulation (600 mg/kg) significantly reduced the serum overall mean glucose (239+21.35), glycosylated hemoglobin (8.16+0.47) and increased the serum overall mean insulin (12.84+1.28) levels in comparison to positive control group having serum overall mean glucose (356.27±6.57), glycosylated hemoglobin (12.34±0.48) and insulin (6.84±0.71) levels respectively. Moreover, histopathological analysis also supported the antidiabetic potential of polyherbal formulation. Polyherbal formulation enhanced the performance of pancreatic β cells by upregulating the expression of Pdx-1, Ins-1 and Ins-2 (insulin signaling cascade) and down regulating the expression of cellular stress cascade, MAPK downstream c-Jun N terminal kinase (JNK). Conclusively, the results of current study indicated the potent hypoglycemic properties of polyherbal formulation.