مولانا حافظ احمد ؍ مفتی عزیز الرحمن صاحب
یہ مہینہ بھی آہ ماتم کی صدا سے خالی نہیں، شکر کا مقام تھا کہ اب تک دیوبند میں اکابر کی صحبت یافتہ اور اکابر کی زندہ یادگاریں موجود تھیں، مگر افسوس کہ یہ بھی یکے بعد دیگرے ہم سے رخصت ہورہی ہیں، مولانا حافظ احمد صاحب مہتمم مدرسہ عالیہ دیوبند خلف الصدق حضرت مولانا محمد قاسم صاحب رحمۃ اﷲ علیہ گزشتہ مہینہ حیدرآباد میں سپردخاک ہوئے اور اب اس مہینہ ۱۸؍ جمادی الثانی ۱۳۴۷ھ کو دائرہ قاسمیہ کے مفتی اعظم حضرت مولانا عزیز الرحمن نے ۷۲ برس کی عمر میں دیوبند میں بمرض فالج انتقال کیا۔ اِنَّا لِلّٰہِ وَ اِنَّا اِلَیْہِ رَاجِعُوْنَ۔
مرحوم نے مولانا مملوک العلی صاحب اور مولانا فضل رحمان صاحب گنج مراد آبادی، اور مولانا رشید احمد صاحب گنگوہی سے ظاہر و باطن کا فیض اٹھایا تھا، کم سخن، متین، حلیم اور سادہ مزاج تھے، تقویٰ اور دینداری، ان کے چہرہ کمال کا خط و خال تھی، حدیث کی درس و تدریس کے ساتھ کتب فقہ کی جزئیات پر ان کی وسعت نظر بدرجہ اتم تھی، فتاویٰ کے جوابات مختصر لیکن قل و دل دیتے تھے اور بیالیس برس تک اس خدمت کو انجام دیا۔ ایسے متقی اور محتاط فقیہ اور محدث آئندہ کہاں پیدا ہوں گے۔
زمانہ کا رنگ پلٹ رہا ہے، انقلاب کی لہریں دیواروں تک پہنچ گئی ہیں، جن کے رہنے والے زمانہ کے اس سیلاب سے اپنے گوشۂ عافیت کو محفوظ سمجھتے تھے، علماء کے خیالات بھی بدل رہے ہیں، اختلاط، میل جول اور مبادلہ آرا سے ان کے نقطۂ نظر میں بھی فرق آرہا ہے، یہ زمانہ علمائے اسلام کے لئے حد درجہ نازک ہے، ایک طرف تو تقویٰ، دینداری، اسلام کی اصلی روح کی حفاظت اور دوسری طرف نئے نئے مسئلے، نئے نئے فتوے اور نئے نئے سوال...
The Benazir Income Support Program (BISP), introduced in 2008-09, is a unique cash support scheme for economically stressed families. Its uniqueness arises from several facets. The cash transfers are provided only to women aged over 18 years and have been ever married. It is unconditional and aimed at supplementing income as opposed to alleviating poverty. It was politically neutral, given that the facility to identify potential beneficiaries was extended to all parliamentarians, irrespective of party affiliation. A set of filters, applied electronically, ensured objectivity in beneficiary selection. Disbursement mechanism was automated to ensure minimal leakage. This paper outlines the process of the preparatory work that went into designing BISP – the conceptual debates, the beneficiary identification and disbursement procedures, etc. – involving a combination of high quality research with political decision making. It also addresses the debates surrounding BISP, cites independent empirical studies that show that the parliamentarian-based beneficiary selection mechanism was efficient and equitable and did indeed cover the deserving, and also responds to the variety of criticisms. ______
Accelerated research in the field of Co-ordination chemistry has vitalize the scientists world over to consider transition metals as possible powerful agents to enhance the pharmacological activities of different drugs. Additionally, it has been explored that accompaniment of transition metal ions to a drug not only potentiates the already known pharmacological action of the drug but may also be responsible for exhibition of newer activities of the compound unnoticed hitherto. Medicinal inorganic chemistry is flourishing with successful clinical application of many metal complexes. Based on these findings the present work aims at synthesizing various transition metal complexes of some reputable and well practiced pharmacological agents. The drugs included antimicrobial agents, Isoniazid and Pyraziamide, antihypertensive agent, Losartan, antimycotic Fluconazole and oral hypoglycemic agent, Biguanide Metformin. Copper, Nickle, Cobalt, Mangnese, Iron and Cadmium ions were used for complex formation. The structures and characterization of all synthesized complexes were established and characterized by using FTIR, UV-visble, NMR, elemental analysis, AA, SEM and XRD data and their physicochemical properties was done by melting point, color, solubility, conductance and magnetic susceptibility values. The metal complexes of Isoniazid and Pyrazinamide were evaluated for their antimycobacterial activity against Mycobacterium strains resistant to commonly used anti tuberculous agents. Furthermore, all complexes were evaluated for their cytotoxic, antiplatelet and antibacterial activities. Cobalt complex of Pyrazinamide were found active against all resistant tuberculous mycobacterium strains while the Mangnese complex of this drug showed anti mycobacterial activity against two of the strains. All complexes of Isoniazid demonstrated activity against resistant strains of Mycobacterium Tuberculosis, Copper complex of Fluconazole exhibited cytotoxic activity against all four cancer cell lines whereas Cobalt and Iron complexes were cytotoxic against KB-3-1 cancer cell line. Pure Losartan was also found to be cytotoxic against cervical carcinoma cell lines. Contrary to these findings, Biguanide metformin metal complexes were inactive in terms of cytotoxic, antibacterial and antipletelet activities depicting no encouraging results.