Factors Affecting the Failure of Patient Safety Target Indicators in the Regional Hospital of the Datu Beru Takengon Central Aceh

The application of patient safety management is very important in an effort to prevent or minimize the occurrence of adverse patient safety incidents. The purpose of this study was to identify the factors that influence the achievement of patient safety target indicators. The method is a quantitative observational study with a cross sectional study approach. The study population was a nurse who worked in the inpatient room with a sample of 60 people who were taken by purposive sampling. The statistical test used is Multiple Linear Regression Analysis. The results of the Multiple Linear Regression Test show that knowledge, communication systems, commitment and experience (regression coefficient values ​​of 0.164, 1.1192, 0.528 and 1.169 have a positive influence on the achievement of patient safety goal indicators and leadership, risk management systems and reporting systems have a significant influence. Negative impact on the achievement of patient safety target indicators (regression coefficient values ​​of -0.064, - 0.967 and -0.281). The results of the t test were obtained that the communication system is the dominant factor that has a significant effect on the achievement of the patient safety goal indicators. Significant towards the achievement of patient safety target indicators. It is expected that input or consideration for the hospital in evaluating and improving hospital policies in increasing the achievement of patient safety target indicators is in accordance with existing targets.

Structural Elucidation, Bioassay and Pyrolytic Characterization of Coordination Compounds With Novel Schiff’S Bases

This research work was planned to synthesize and characterize transition metal complexes of some biologically active Schiff base chelating agent and then to investigate their antimicrobial and antioxidant activities. The ligands (L1-L5) are the modified forms of pyridine-3-carbaldehyde containing azomethine linkage which is of considerable importance in coordination chemistry. All the ligands were synthesized by reacting pyridine-3-carbaldehyde with primary amines. The structure of the newly synthesized amines were established by IR, NMR, Mass and elemental analysis. The ligands formed complexes of the type [MLX 2 ]. The comparison of the IR spectra of ligands and their metal complexes suggested that pyridine-3-carbaldehyde-N and amine-N are involved in the coordination with the metal ions. The UV-visible spectra of the complexes indicated the tetrahedral geometry for Co(II), Ni(II), Cu(II) and Zn(II) complexes. The antibacterial and antifungal activities of all the compounds were tested against the gram negative bacteria Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa, gram positive bacteria Bacillus subtilis, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumonia and fungal strains Aspergillus Fumigatus, Aspergillus Flavus and Fusarium Solani. Antioxidant activities including Free Radical Scavenging Assay, Nitric Oxide Scavenging Activity, Hydroxyl Radical (OH) Scavenging Activity and Reducing Power were also carried out. Thermal stability of the compounds was studied through TG/DTA.