Relationship Between Organizational Culture and Employee Performance Through Work Stress at the Regional Office of the East Java I Directorate General of Customs

This study aims to analyze the Relationship between Organizational Culture and Employee Performance through Work Stress at the Regional Office of the Directorate General of Customs and Excise, East Java I. This research method is an explanatory research, the analysis unit in this study is employees who work in the Directorate General of Customs and Excise Office. East Java I region, which consists of 80 structural officials, 79 functional officials and 1323 executive staff. The method of collecting research data using a questionnaire. The results showed that organizational culture affects the work stress of employees at the Regional Office of the Directorate General of Customs and Excise, East Java I, this shows that organizational culture is able to increase the work stress of employees of the Regional Office of the Directorate General of Customs and Excise, East Java. Organizational culture influences the performance of the employees of the Regional Office of the Directorate General of Customs and Excise, East Java I, this shows that with a good and appropriate organizational culture, it is able to increase the performance of the employees of the Regional Office of the Directorate General of Customs and Excise, East Java I. New organizational culture that also improves Employee stress, namely the imposition of input into daily work activity reports by employees in the daily logbook through an internet-based application with details on the types of activities, time norms, achievement targets and employee daily problems for all levels of employees, both structural, functional and executive.

Association Study Between Vitamin D Receptor Gene Apai Polymorphism and Osteoporosis in Population of Lahore

Osteoporosis is known as a chronic and systemic bone disorders. Osteoporosis xiv destroys the bone microarchitecture tissues thus bone becomes so weak that leads the high risk of fractures. Mostly women are affected than men. Osteoporosis and its related fractures has become serious problem in Pakistani elder population and according to survey the prevalence of osteoporosis in our country is 9.9 million and 7.2 million out of them are osteoporotic women. Genes of Vitamin D receptor (VDR) consider as candidate gene for bone mass regulation in osteoporosis. The current study examined the VDR gene polymorphism (ApaI) on PCR-RFLP based on hundred samples among the population of Lahore, city of Pakistan to determine prevalence of osteoporosis and compare the frequency of osteoporosis between genotype and allelic sub-groups. The analysis showed that the single nucleotide polymorphism (SNP) followed HardyWeinberg equilibrium (HWE) that p > 0.05. No significant association was found among case and controls for allelic and genotypic frequency. The case and controls both have almost same frequency of AA, AC and CC genotype. Almost same allelic (A and C) frequency of ApaI also demonstrated no significant association among case and controls. Therefore it was observed that ApaI polymorphic site on VDR gene has no significance relation for osteoporosis in studied patients (p> 0.05). The current study recommended that ApaI VDR genotype could not be candidate gene leading to osteoporosis. The current study is also tried to uncover its associated risk factors that Phosphorus has significance association (p =.006) with normal?and patient (by an independent-sample t-test) hence it has also significant association (p =.026) with age groups (by ANOVA). It means that phosphorus has key function for bones development and bone strength