حرية الفكر والتعبير عند الإمام بديع الزمان سعيد النورسي رحمه الله

The freedom of thought and expression has acquired a diversity of meanings and limitations determined by the evolving socio-historical contexts of various civilizations through the history. This piece of research briefly investigates the history of evolution of this concept in Islamic and Western intellectual circles and then intends to focus upon the elaboration of this idea by Imam Badi-uz-Zaman An-Naurasi. Iman Naurasi supports the human right of thinking and expressing ideas freely but at the same time recognizes the need of divine intervention in delimiting its boundaries. Humans, if left entirely unrestricted to make their choices in life, would only bring about disastrous results and thus lead to cessation of a collaborative social life. Therefore, Imam proposes that humanity should abide by some universal principles and high moral values inspired by the divine revelation so that the society could collectively ensure the pursuit of human progress and well-being. Imam proves his point through the instances from the Islamic history that divinely guided freedom of thought and expression provided the world with a vivid model of life which provided people the rights of choosing everything in their life ranging from faith to marital and economic decisions.

Development, Characterization and In-Vivo Evaluation of Emulgels Containing Avocado and Kiwi Fruit Extracts

Nowadays, considerable attention has been given to those plants which have highest antioxidant value because they are used for the treatment of various dermal disorders such as acne, inflammation, hyper pigmentation, dry skin and for aging. They are also used as sunscreens, moisturizing and smoothing agents as synthetic agents have various adverse effects. The aim of the present study was to formulate and evaluate a thermodynamically stable carrier system which contains Persia americana and Actinidia deliciosa fruit extract and used as topical oil-in-water emulgels. Their characterization was done through in-vitro studies and was evaluated through in-vivo studies upon facial skin of healthy human female volunteers.Extracts of fruits i.e Persia americana and Actinidia deliciosa were prepared successively and the antioxidant activity of both fruits were determined by DPPH (2,2, diphenyl-1-picryl-hydrazyl) assay. The antioxidant activities of Persia americana and Actinidia deliciosa fruit extracts were 84% and 79% respectively. Total phenolic and flavonoid contents of both fruit extracts were determined by qualitatively and quantitatively. Suitable oil-in-water type of emulgels E1 containing 4% Persia americana fruit extract, E2 containing 5% Actinidia deliciosa fruit extract and E3 containing combination of 2% Persia americana and 2% Actinidia deliciosa fruit extracts and a base emulgel containing no fruit extract were prepared. All theses emulgel formulations were kept at four different stability storage conditions i.e at 8˚C, 25˚C, 40˚C and40˚C+ 75% RH for study duration of 3 months to observe the following physical parameters like colour, odour, thickness, pH, conductivity, centrifugation, rheological parameters and SEM (scanning electron microscopy). This study was performed according to the criteria of stability guidelines. In-vivo characterization of emulgel formulation was done by applying these formulations on facial skin of healthy human female volunteers for study duration of 3 months to evaluate the following parameters i.e skin melanin, erythema, moisture, sebum, elasticity, Surface evaluation of living skin (skin scaliness, smoothness, roughness and wrinkles) and R parameters of elasticity through cutometer. The study was single blinded and controlled with three groups of active formulation (E1, E2 and E3) and each group having 13 female volunteers. The statistical analysis was done through two- way ANOVA at 5% level of significance and also through paired sample t-test. Active formulations showed significant decrease in skin melanin contents, skin erythema contents, skin sebum contents while a significant increase in skin elasticity and skin moisture contents were observed with respect to base. Active emulgel formulation also showed a significant effect on SELS parameters in increasing the skin smoothness and a significant effect was also observed in decreasing the scaliness, roughness and wrinkleswith respect to base. Therefore it can be concluded from this study that active formulations (E1, E2 and E3) were found completely safe and effective to be used as anti-aging and skin whitening agent by improving the patient compliance.