اسلام امن کا پیغام
نحمدہ ونصلی علی رسولہ الکریم امّا بعد فاعوذ بااللہ من الشیطن الرجیم
بسم اللہ الرحمن الرحیم
معزز سامعین اور میرے ہم مکتب شا ہینو!
آج مجھے جس موضوع پر لب کشائی کی سعادت حاصل ہورہی ہے وہ ہے:’’اسلام امن کا پیغام‘‘
صدرِذی وقار!
اسلام کے معنی سلامتی کے ہیں، اسلام کو سچے دل سے قبول کرنے والا سلامتی میں ہوتا ہے، اسلام کے جملہ احکام سلامتی کا ہی درس دیتے ہیں۔ اس پرعمل پیرا شخص میدان امن و آشتی میں نہ صرف داخل ہوتا ہے بلکہ امن و آشتی کا پیامبر بن جاتا ہے۔
جنابِ صدر!
حدیث نبویؐ ہے کہ’’ المسلم من سلم المسلمون من لسانہ ویدہ‘‘ مسلمان وہ ہے کہ جس کے ہاتھ اور زبان سے دیگر مسلمان محفوظ رہیں ،کسی کو اس کی زبان سے گزند نہ پہنچے کسی کے جسم کے عضو سے اس کو جسمانی یا روحانی پریشانی نہ ہو، اسلام کی ابدی تعلیمات امن و آشتی کے پیغام سے مملو ہیں۔
صدرِمحترم!
ایک مسلمان دوسرے مسلمان کی طمانیت اور سکون کا خواہاں ہوتا ہے۔ اس کی خوشی اور مسرت کا متمنی ہوتا ہے، اس کی تکلیف دور کرنے میں اس کاممد و معاون ہوتا ہے۔ اس کے مسائل کے حل میں کوئی لمحہ ضائع نہیں کرتا۔
جنابِ صدر!
ایک حقیقی مسلمان، مسجد میں ہو، عدالت میں ہو، فیکٹری یا کارخانے میں ہو ،بازاریا دربارمیں ہو، دکان یا مکان میں ہو، سفروحضر میں یا کھیت وکھلیان میں ہو، ہمہ وقت امن و آشتی کا مجسمہ نظر آتا ہے۔ اس کے خدوخال بھی امن سکون کا نمونہ فراہم کر رہے ہوتے ہیں۔
جنابِ صدر!
اسلام کی تعلیمات جس خطہ ارضی میں پہنچیں ، وہاں ظلم و استبداد کے بادل چھٹ گئے،قہر و غضب کے طوفان ختم ہو گئے ، عداوت وخصومت کے جھکڑ چلنا بند ہو گئے ،...
With advancement in the modern world, psychological issues, including anxiety and depression has become the leading cause of mental illness. Herbal products have been explored to observe their effects in helping such conditions and citrus fruits are found to be among these helping tools. To study this, current research was designed to explore the antidepressant effects of Citrus paradisi in various doses on rodents. Swiss Albino mice were used and fresh extract of Citrus paradisi was prepared. Imipramine was used as the standard drug. Ethical approval was taken from the Board of Advanced Studies, University of Karachi. The animals were divided into controlled, standard and test groups. All the animals were recruited from the animal house of University of Karachi. Forced Swimming Test was used to analyses the efficacy. It is a standard test, which is commonly used to evaluate the behavioral response in animals using a cylinder at room temperature. After the completion of dosing and monitoring the animals for 30 days, it was observed that marked improvement in the test animal’s behavior with significant p-values indicating that the extract has improved the animal’s psychological response towards the external stress and animals showed noteworthy improvement in the mobile phase as compared to the immobile phase. It can be concluded from the experimental results that protocol established in this study can be used as an alternative for patients suffering with depression as an herbal option, keeping in mind the other co morbidities of patient and drug interactions of Citrus paradisi.
The main objectives for this study were to determine the molecular basis of the disease resulting in the particular clinical phenotype of thalassemia intermedia in Pakistan, to identify the factors affecting genotype – phenotype relationship, to determine the possibility for a consistent prediction of phenotype severity from the genotype factors and to asses their relative importance. Thalassemia Intermedia is clinically and genetically heterogeneous and the genotype is retrospective. However, the disease being of milder form is characterized by late commencement of transfusion, lesser degree of anemia and greater survival time. In this study one consistent factor having a fair ground for the classification was the age of the patient at presentation. Age of the patients in this study was between 2.5 – 36 years. These patients in the radiance of presentation were grouped in four categories; Severe, Moderate, Mild and Very Mild depending on the transfusion commencement. Eleven different beta chain mutations were identified, IVSI-5 = 46 %, Fr 8-9 = 11.5 %, Cap+1 = 10%,, Cd30 = 7.0%, IVSI-I 6.5%, HbE = 6%, HbS = 3%, Del 619 = 1.5 %, Cd15 = 1.0%, Fr 41 – 42 = 0.5%, Fr16 = 0.5% and δβ = 5%. However, 1.5 % of the alleles remained unknown. Out of 100 samples tested for Xmn-I polymorphism 79 were found to be positive, 36 % for +/+ genotype and 43% for -/+ genotype and 21% were negative for the genotype. The samples were also tested for δβ mutations and 5 of them were found to be homozygous. Deletions for α- chain were observed in 30% of the samples, all of them had α3.7 deletions out which 8 % had - α/ - α deletions , 21% had -α/αα deletions and 1% had - - / - α deletions (Table 3.46). Frequency of Alpha Thalassemia in different ethnic groups were determined which revealed that alpha thalassemia mutations are more prevalent in Sindhis, Punjabis and Mahajirs. Relating phenotype to genotype is complicated by complex interaction of the environment and other genetic factors such as coinheritance of other hemoglobin mutations. Alpha thalassemia and Xmn-I predominantly contributed the phenotype. Hemoglobinopathies account for only 9% of the patients. Compound heterozygosity was another factor involved particularly with the assistance of Xmn-I polymorphism and coexistence of α- Thalassemia. Xmn-I +/+ and Hemoglobin S mutation accounted for 9% of cases. To establish a comprehensive diagnosis program the problem of detection of an ability to produce fetal hemoglobin, inheritance of β+ Thalassemia genes and inheritance of α Thalassemia and other factors ameliorating the disease should be defined and incorporated. Molecular basis of thalassemia intermedia as defined in this study explains the involvement of different factors that tend to develop the disease phenotype. However, no single factor finds an authority for the discipline of mildness and thus require cooperation of the elements serving in amelioration.