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Interleukin-6 Gene Polymorphism Study in Patients With Cardiomyopathy

Thesis Info

Author

Amna Didar Abbasi

Department

Department of Biochemistry, QAU

Program

Mphil

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2012

Thesis Completion Status

Completed

Page

xi, 62,

Subject

Biochemistry

Language

English

Other

Call No: DISS/M.Phil. BIO/3137

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676715008123

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پروفیسر اسنوک ہرخر دنئے

پرنس کائتانی ؍ پروفیسر گویدی ؍ پروفیسر اسنوک ہرخردنئے
امسال مرحوم مارما ڈیوک پکتھال کے علاوہ ن کو ہم سب جانتے تھے، کئی نامور مستشرقین نے وفات پائی، اٹلی کے پرنس کائتانی اور پروفیسر گویدی اور لائڈن کے پروفیسر اسنوک ہر خردنئے نے امسال ہماری دنیا کو الوداع کیا، پرنس کائتانی تاریخ اسلام کے عالم اور گویدی عربوں کے ریاضیات اور جغرافیہ کے ماہر اور اسنوک ہر خردنئے ’محمڈنزم‘ نامی کتاب کے مصنف ہیں جس کو انھوں نے خطبہ کی صورت میں امریکہ کی ’’مجلسِ تاریخِ مذاہب‘‘ میں پیش کیا تھا اور بھی دوسری کتابیں اور مضامین ان کے قلم سے نکلے تھے۔ (سید سلیمان ندوی، اکتوبر ۱۹۳۶ء)

COMPARISON OF REGIONAL MANUAL THERAPY AND STANDARD PHYSICAL THERAPY INTERVENTION IN FEMALES WITH SACROILIAC JOINT PAIN

Background and Aim: Sacroiliac joint pain is localized in the region of sacroiliac joint which can be increased by stress and provocation tests of the joint. Aim of this study was to compare two interventions for reduction of sacroiliac joint pain. Methodology: Study design was randomized clinical trial. Study was conducted in bajwah hospital and children polyclinic Lahore. Duration of study was six months. The total sample size was 64 patients. Females of 20-50 years old with diagnosed sacroiliac joint pain were included in this study. Compression and distraction objective tests were performed for further confirmation of sacroiliac joint pain.  Purposive sampling technique was used. Numeric pain rating scale (NPRS) and Oswestry low back disability questionnaire (ODI) were used to collect the data. Exclusion criteria was females with fractures and other abnormalities of spine. Results: Results showed that both groups were equal when assessed on baseline by normality test colmogorov-smirnova. Independent t test was applied to compare the mean value of NPRS. Pretreatment mean of NPRS scale for both the regional treatment and standard treatment groups was 7.After 4 weeks NPRS of regional treatment group was 4 and of standard treatment group was 7. The mean value of pretreatment ODI for regional treatment group was 33 and for standard treatment group was 34.After 4 weeks ODI of regional treatment group was 24 and mean of standard treatment group was 27. Conclusion: It is concluded that after giving equal sessions to both groups when results were assessed regional treatment is more effective than standard treatment.

Microorganisms Causing Urinary Tract Infection Uti &Amp; Their Susceptibility Among Children Aged 0 to 5 Years at French Medical Institute for Children, Kabul Afghanistan

Introduction: Urinary tract infections (UTI) are the common medical problem affecting children that lead to frequent clinic visit and hospitalization. Undiagnosed, untreated UTI may lead to renal scoring, hypertension and end stage renal disease, early detection and treatment of UTI in children must be prompt. Objective: To isolate the causative organisms causing UTI among children of 0-5 years of age and to determine the antibiotic susceptibility of the isolated microorganisms. Methodology: Clinical data and outcome were prospectively analyzed for 140 patients with confirmed diagnosis of urinary tract infection (UTI) based on urine culture and sensitivity report. The data collected from June to August 2015 and the study done on Afghan children who were aged between 0 to 5 years included data of outpatients and admitted patients came to clinic at FMIC Kabul Afghanistan. Results: A total of one hundred and forty (n=140) children aged 0 to 5 years with UTI were included in this study. Out of 140 patients, 94 (67.14%) were female, while 46 (32.82%) were male. Escherichia coli (E.coli) were the most common isolated uropathogen. out of 89 cases of E.coi; 62.14 % cases showed their highest sensitivity to Augmentin, Aminoglycosides and third generation cephalosporin while, 37.86% exhibited their extended spectrum beta lactamase (ESBL) properties which, showed their highest sensitivity to Amikacine, Fosfomycine and Imipenem. The second common uropathogen was Klebsiella pneumonia 7.86% followed by Serratia odorifera 7.14%, Enterococcus 5.71%, Proteus 6.46% and others 9.29%. Conclusion: Culture conformation and proper treatment of the organisms causing UTI in children is the key to success. E.coli is the leading uropathogen which showed its highest 7 sensitivity to Augmentin, Amino glycosides and third generation cephalosporin which are still the most suitable agents for empiric therapy in pediatric UTI. At the hospital setting, E-coli and Klebsiella pneumonia were the organisms that exhibited extended spectrum Beta- lactamase (ESBL) properties which revealed that, resistance to commonly used antibiotics is on the rise. The treatment recommendations of community acquired uropathogen should be based on individual urine culture conformation and sensitivity result.