تعارف پس منظر:
غالب کے آباؤ اجداد ترکی سے تعلق رکھتے تھے اور ان کا شمار ایبک قوم سے تھا۔غالب کے دادا قوقان بیگ ہندوستان ہجرت کر کے آئے۔یہ دور مغلیہ سلطنت کے زوال کا دور تھا۔
پیدائش:
۷۲ دسمبر ۷۹۷ ۱ء کو آگرہ میں پیدا ہوئے ان کا پورا نام بمع خطا بات مرزا اسد اللہ خان غالب (تخلص /خطاب) نجم الدولہ دبیر الملک نظام جنگ بہادرعرف مرزا نوشہ تھا۔والد کے انتقال کے بعد چچا نصراللہ بیگ نے پرورش کی آٹھ سال کی عمر میں چچا بھی وفات پا گئے۔ ان کی وفات کے بعد ننھیال رہنے لگے۔
ازدواجی زندگی:
۳۱ برس کی عمر میں نواب احمد بخش خان کے چھوٹے بھائی نواب الہی بخش خان معروف کی ۱۱سالہ لڑکی امراؤ بیگم سے شادی ہوئی۔ اللہ نے سات بچوں سے نوازا لیکن وہ سبھی بچپن میں وفات پا گئے اور بیگم کا بھی انتقال ہو گیا۔غالب ۱۵ فروری ۱۹۶۹ ء میں ۷۲ برس کی عمر میں ظہر کے وقت انتقال کر گئے۔
ابتدائی حالات:
غالب جس دور سے تعلق رکھتے ہیں وہ مسلمانوں کے زوال کا دور ہے اس وقت حکومت کا مرکز دلی تھا۔اس دور میں بادشاہوں کی حیثیت بہت معمولی ہو گئی تھی مغل بادشاہ شطرنج کا مہر بن گئے اور آہستہ آہستہ سکھو ں،جاٹوں اور روہیلوں نے زور پکڑنا شروع کیا اور اس حکومت کو گرانے میں اہم کردار ادا کیا۔ ۱۷۳۹ء میں نادر شاہ نے دلی پر حملہ کیا۔۱۷۴۸ء سے لے کر ۱۷۶۱ء تک احمد شاہ ابدالی نے بہت سے حملے کیے اور مغلوں کی رہی سہی طاقت بھی ختم کر دی۔ احمد شاہ ابدالی نے ان حملوں میں مرہٹوں کی کمر توڑ کر رکھ دی۔اس سیاسی تاریخی پس منظر میں غالب نے ہوش سنبھالا غالب کا تعلق رئیس لوگوں کے ساتھ تھا ان کی پہنچ بادشاہوں کے دربار تک تھی۔
تہذیبی...
Background and Aims: To explore the prevalence of neuropathic hand pain in young adults and how it affects hand functionality.
Methodology: A convenience sampling was used to conduct a cross-sectional study on 192 medical students aged 18 to 28 years from October 2022 to March 2023. The purpose of the study was to evaluate the prevalence of neuropathic hand pain in young adults and how it affects hand functionality. Both the Duruoz Hand Index and the Douleur Neuropathique Four Questionnaire were used.
Results: This study included 192 participants, the majority of whom were females (84%) and aged 20-24 years. 16.1% of participants reported having had surgery or an injury to their upper limb in the past. Participants described neuropathic pain symptoms such as electric shocks (21.4%), burning pain (18.2%), and painful cold (15.6%).
Limitations and Future Implications: A small sample size and a focus on a particular group of medical students may restrict the generalizability of the findings. To improve the generalizability of the findings, future research should replicate these findings using larger sample sizes and diverse populations. Insights into the development and chronicity of neuropathic hand pain in young adults may also come from longitudinal studies.
Conclusion: Our study demonstrates the prevalence of neuropathic hand pain in young adults and how it affects hand functionality. Female participants were more likely to experience pain and functional hand impairments.
Thermoluminescent dosimeter (TLD) is a device used to evaluate integrated dose of ionizing radiation. Natural mineral topaz as a thermoluminescent (TL) material has been studied for radiation dosimetry. The northern area of Pakistan along with Himalayas, due to its geological settings, is rich in topaz which is found in pegmatite rocks. Four mines namely: Kharguluk, Nyit, Sabser, and Yono in district Skardu were selected for sampling of topaz. Relatively big pieces of topaz were converted into chips and powder of micron size. Pellets of topaz composite with glass 1:2 wt.% and teflon 2:1 wt.% were prepared by compressing and sintering. The mineral was recognized as topaz through phase identification by XRD (X-ray diffraction). The mineral collected from Kharguluk mine was not topaz rather mixed with quartz. The elemental analysis by the XRF (X-ray fluorescence) of topaz of understudy mines resulted about 56.554, 22.030, 11.293, 9.560 and 0.453 at.% of the elements O, Si, Al, F and H. These results confirmed the mineral as topaz. The irradiation of topaz pieces with fast neutrons and thermal treatment produced deep and London blue colours in topaz. The TL response of virgin topaz of understudy mines generated a single huge peak in glow curve at temperature around 250 oC, which is the gesticulation of topaz. The INAA (Instrumental Neutron Activation Analysis) of topaz from the three mines detected the elements Na, Ga and Cs in three mines, while As and Sb were detected in Yono and Nyit mines respectively. The photoinduced emission spectra of topaz powder from three mines at the excitation wavelength 230 nm produced two bands. One band is at 430 nm and other at 470 nm which are the characteristics of topaz. The pellets of the composites were sintered at 400 to1200 oC. The TL response of the composites and [OH]/[F] ratio decreased with increasing sintering temperature. The optimum temperature selected for preparation of topaz composites was 900 oC. The effect of ultraviolet (UV) and visible light on topaz revealed that UV and visible light contribute to phototransference of charge. The TL glow curves of topaz chips, topaz-glass and topaz-teflon composites showed stable peaks (dosimetric peaks) at about 250-260, 250-260 and 257-265 oC respectively. Initially, the fading was maximum (27-30 %) and became 6-9% after few days. Chips and pellets showed the linearity with dose, good reproducibility, independent dose rate, linear dose response and strong energy dependence below 600 keV. The chips and pellets were found suitable for dosimetry for dose greater than 0.01 Gy at high energy beams. Saturation in the TL response was observed above 2000 Gy. The pellets of topaz-glass showed better mechanical stability than topaz chips and topaz-teflon pellets. The cutting of topaz chips was found difficult and time consuming, while the preparation of pellets of topaz-glass and topaz-teflon was relatively easy. Topaz-glass showed better TL dosimetric features as compared to topaz chips and topaz-teflon composites. These are recommended to be used at the facilities where high radiation doses are involved. The TL analysis of the glow curves using IRM (Initial Rise Method), Tm-Tstop, PSM (Peak Shape Method) and VHR (Variable Heating Rate) method showed that topaz and its composites with glass and teflon follow second order kinetics. The thermal activation energies 0.976- 1.576 eV for natural topaz were found to be greater than 0.488-0.627 eV for topaz- glass and 0.447-0.616 eV for topaz-teflon. The thermal activation energy found by VHR was 1.35 times higher than determined by PSM and IRM. The OSL (optical stimulated luminescence) dosimetric characteristics of the pellets of topaz-glass and topaz-teflon composites were studied for various energy beams of photons and particles using CW (continuous wave)-OSL mode. Blue light as a stimulation source for OSL generated a rapid decaying response within 10 s and then a long non-zero tail was observed. The integrated OSL (IOSL) response met the dosimetric requirements for topaz-glass and topaz-teflon at dose greater than 0.01 Gy and 1.0 mGy respectively. The TL response of topaz before and after OSL measurement showed two peaks in the glow curve at the same position. After OSL measurement, decline of about 1.35 times less in intensity of peak 2 was observed. Radiation dose was measured at IPEN, Brazil with the TLDs: LiF, topaz- chips and the composites of topaz-glass and topaz-teflon. Using the respective calibrations curves and applying the fading corrections, the measured dose proved that topaz and its composites are suitable for radiation dosimetry at high radiation areas. The price of topaz based TLDs is less than commercial dosimeters. Topaz-glass and topaz-teflon pellets can be recommended for the measurement of dose greater than 0.01 Gy by the TL method, while topaz-teflon are suitable for dose greater than 1.0 mGy using OSL read out. Further exploration of topaz from other mines of Pakistan, their TL/OSL analysis and applicability at sterilization, irradiation and medical centres is strongly recommended.