قاری سید صدیق احمد صاحب باندوی
۲۸؍ اگست ۱۹۹۷ء کو مشہور عالم ربانی اور مرجع خلائق بزرگ قاری سید صدیق احمد صاحب باندوی نے رحلت فرمائی۔ اناﷲ وانا الیہ راجعون۔
وہ ضلع باندہ کے ایک گاؤں ہتھورا کے رہنے والے تھے جو علمی و تمدنی حیثیت سے بہت پس ماندہ تھا، انہوں نے مظاہر العلوم سہارنپور میں تعلیم حاصل کی اور مولانا اسعد اﷲ صاحب خلیفہ حضرت تھانویؒ سے بیعت ہوئے اور اجازت و خلافت حاصل کی، تعلیم سے فراغت کے بعد اپنے وطن سے قریب فتح پور میں مفتی ظہور الاسلام صاحب کے مدرسہ میں مدرس مقرر ہوئے مگر کچھ ہی دنوں بعد ان کے گاؤں ہتھورا اور اس کے گردونواح میں ارتداد کی لہر پھیل گئی۔ چنانچہ قاری صاحب نے اپنے گاؤں میں بڑی بے سروسامانی کے عالم میں ایک مدرسہ کی بنیاد ڈالی اور اس فتنہ کی سرکوبی کے لیے سرگرم عمل ہوگئے، ان کی یہ اصلاحی کوشش بارآور ہوئی اور جو خطہ ارتداد کی لپیٹ میں آچکا تھا اب وہ مرکز علم و رشد بنا ہوا ہے، جہاں دور دراز سے طلبہ اور علوم نبوت کے شائقین رختِ سفر باندھ کر آتے ہیں۔
قاری صاحب اچھے معلم و مدرس ہی نہ تھے بلکہ ایک داعی و مصلح بھی تھے، اس کی وجہ سے علوم دینیہ کی تحصیل کے لیے آنے والوں کے علاوہ ہر وقت طالبین و سالکین کا جمگھٹ ان کے یہاں لگا رہتا تھا اور ہر ایک بقدرِ استعداد ان سے فیضیاب ہوتا تھا۔ مشرقی اضلاع کے لوگوں کو ان کی تذکیر و ہدایت سے خاص طور پر بڑا فائدہ ہوا۔
راقم الحروف جامعہ عربیہ ہتھورا میں حاضری کے موقع پر ان کی مشغول زندگی کا خود مشاہدہ کرچکا ہے، نماز فجر کے بعد سے ظہر تک طلبہ کی ایک جماعت ان سے سبق پڑھ کر جاتی تو خالی گھنٹے...
Vivekananda was the Hindu revivalist of nineteenth century who preached the message of equality of all religions. In his lectures, he guided people to assimilation of religions and not their destruction. He emphasized on peace and harmony of religions that could only be attained through tolerance. This paper explores his claim of equality of religions from his writings regarding two religions - Christianity and Islam. Critical approach is utilized to identify the fact that either he is equating all religions or he is trying to submerge the non-Hindu religions in his philosophy of neo-Vedanta. Apparently, the tension between these two positions makes his theory of pluralism suspicious. In other words, his popular image of being a pioneer of religious pluralism needs to be reassesses by studying his writings and presentation of the beliefs, rituals, and practices of other religions, as well as, his practical interactions with the followers of different religions during his life. In this connection, it is important to explore how he perceives and depicts the personalities of Jesus Christ and Muhammad.
The technetium ( 99m Tc) radiopharmaceuticals have been used for diagnosis of many diseases especially cancer in nuclear medicine for many years ago. Currently, target specific radiopharmaceuticals containing peptides have become more interesting due to increasing the knowledge of receptor binding affinity of specific peptides as well as ease of chemical modification of peptide sequences. Many chelators have been developed as bifunctional chelators for 99m conjugation to peptides as well as for chelation with Tc. Small size chelators are desireable for labeling the small peptides. One of the most important requirements of radiopharmaceuticals is an aqueous phase labeling the biomolecules to 99m Tc. These requirements must meet in order to use for nuclear medicine. In this context, cyclopentadiene (Cp - ) is obviously as a good choice of chelator due to its small size and low molecular weight. The 99m Tc radiolabeled peptide comprising Cp - core have not been synthesized in an aqueous phase. Instead, they have been synthesized by double ligand transfer approach in an organic solvent using harsh reaction conditions which are still not suitable for routing use. In this study we describe the syntheses of half-sandwich complexes of the type [h 5 -Cp(CONH-R)M(CO) 3 ] with M=Re or 99m Tc. The R group represents different tri-peptides which display high binding affinities for oligopeptide transporters PEPT2 and cyclic RGD peptides which have high binding affinity with integrin family receptor. The 99m Tc complexes [(h 5 - CpCONH-R) 99m Tc(CO) 3 ] were prepared directly from [ 99m Tc(OH 2 ) 3 (CO) 3 ] + and Diels-Alder dimerized, cyclopentadienyl derivatized peptides in an aqueous phase. This approach corroborates the feasibility of metal-mediated retro- Diels-Alder reactions for the preparation of not only small molecules but also of peptides for carrying a [(h 5 -Cp) 99m Tc(CO) 3 ] tag. The Diel-Alder products [(HCpCONH-R) 2 ] containing selected peptides were synthesized from Thiele’s acid [(HCp-COOH) 2 ] via double peptide coupling. The peptides of different sequences in this study were prepared through solid phase peptide synthesisxiv (SPPS). The Re-complexes [(h 5 -CpCONH-R)Re(CO) 3 ] were synthesized by attaching [(Cp-COOH)Re(CO) 3 ] directly to the N-terminus amino group of peptides as prepared from SPPS. The authenticity of the 99m Tc-complexes is confirmed by HPLC retention time comparison with the corresponding rhenium complexes, fully characterized by spectroscopic techniques.