Implementasi Aplikasi Presisi Paten Dalam Peningkatan Pelayanan Cepat Dan Tepat

Penelitian ini untuk mengimplentasikan Presisi dalam bentuk aplikasi pelayanan cepat dan tepat Kepolisian Republik Indonesia dengan konsep  prediktif, responsibilitas, transparan dan berkeadilan (PRESISI). Konsep presisi terdapat pencegahan atau prediktif perlu dilakukan dalam upaya pencegahan kejahatan.  Kemudian terkait responsibilitas menekankan bahwa kepolisian memang harus cepat tanggap untuk menangani kasus hukum terkait dengan ketertiban dan keamanan di masyarakat. Dengan era 4.0 penggunaan teknologi informasi dapat membantu kepolisian untuk cepat merespons dan segera menangani segala bentuk laporan yang masuk. Bencana yang melanda dunia pandemic  Covid-19 yang membatasi ruang lingkup berkumpul dalam suatu tempat untuk menghindari tertularnya virus covid-19. Implemtasi aplikasi Presisi adalah menjadi sousi yang tepat dalam melayani perpanjngan SIM. Aplikasi ini di desain untuk memangkas waktu antrian sehingga masyarakat yang memperpanjang  surat izin mengemudi tanpa turun dari kenderaan dengan konsep drive trhu.

Synthesis and Characterization of Palladium Ii Complexes With Thioureas, Heterocyclic Thiones and Phosphine Derivatives

The interaction of thioureas with metal ions has been the subject of numerous recent investigations because of their variable binding modes and because of the relevance of their binding sites to those in living systems. The complexes of palladium(II) in this regard are particularly important because of its similarity to platinum(II) complexes. Forty palladium compounds of formula [Pd(L1)2(L2)2]Cl2, where L1 = thioureas (Tu), Methylthiourea (Mtu), dimethylthiourea (Dmtu), tetramethylthiourea (Tmtu), 2-mercaptopyridine (2Mpy) and 2-mercaptopyrimidine, 6-mercaptopurine and 4-mercaptopyrimidine, L2 = Tri-p-tolylphosphine, Tri-o-tolylphosphine, Benzyldiphenylphosphine, Tris-4-chlorophenylphosphine and cyclohexyldiphenylphosphine have been synthesized by the reaction of K2[PdCl4] to phosphine and after that thiones ligands. The complexes (1), (2) and (3) were also characterized by single crystal X-ray diffraction technique. The spectral and crystallographic data suggest that the complexes show sulphur coordination of thioureas/heterocyclic thiones and phosphorous coordination of phosphines to palladium(II). The geometry of palladium(II) is distorted square planar. The antibacterial activities against bacterial strains were checked using Imipenum as reference. The antitumor ability for MCF7 tumor cell line was found comparable to that of doxorubicin. The investigated compounds have shown a relatively less cytotoxic effect in brine shrimp bioassay study. The antioxidant activity indicate potential for further study. The results designate that palladium complexes with thiones and phosphines ligands should be studied further for their use as anticancer palladium drugs in future.