When we go through the history of Sub-continent it becomes clear that Islam entered in this area during the period of rightly guided Caliphs. In 92 A.H when Muhammad bin Qasim conquered Sindh and some other parts of the present Pakistan, many Tab‘een and some companions came in the Sub-continent. It is famous that Shāh Walī Allāh (d:1176 A.H) is the first person in Sub-continent who translated Holy Qur’an in Persian and urged to ponder over its meanings. But it is not true. Makhdūm Nūḥ Hālāe’ (d:998 A.H/1589A.D) translated the Qur’ān in the Persian language and he must be regarded as the pioneer of the translation works. Shāh Walī Allāh had to face opposition on translating the Holy Book. Later on, his sons followed him produced translations in Urdu. Many scholars have written tafasir (commentaries) of the Quran. When we analyze these commentaries, it seems that influence of different schools of thought is visible on them. Although Hanfi School of Thought is in the majority but there is a division in Hanfis as well. Salfi approach has also influence in Sub-continent. In some tafsir, Sufi approach can also be seen. Moudidi is the first person who presented a theory of political Islam and his tafsir Tafhīm al- Qur’ān advocates this aspect. Hameed-ud-Deen Farahi is the first person in the Sub-continent who highlighted Nazm-e-Qur’an and his student Maulānā Amīn Aḥsan Iṣlāḥī advocated his approach in Tadabbur-e-Qur’ān.
To sum up it can be said that in Sub-continent there is variety of approaches for understanding Qur’an. This is blessing of Allah Almighty that Holy Qur’an is being understood in different ways and every scholar is getting pearls of guidance as per his ability and approach.
Among the prohibited actions, gambling is on the top. There is definite prohibition in many verses of the Holy Quran and the hadiths of the prophet. Despite such strict prohibitions by Islam, the gambling has been entered in economy in different shapes. Among the different types of gambling, some forms are very clear, every one considers it wrong, whereas some kinds of gambling are not considered wrong by the peoples. Whatever the name of gambling is, it is illegal and immoral, because changing name doesnot change its reality. Every type of gambling creates destruction in society and economy and brings various evils with it. Gambling makes man greedy, miser, lover of money, jealousy, wastage of time and money. Such evils takes men away from generosity and worship of Allah, carelesness in his duties and man becomes immoral and irrespossible. Therefore, in any society where gambling is spread, the concept of peace, love, humanity bacomes meaning less. As a result, the poor get poorer and the rich grow richer.
Objective: This was a prospective analytic study that aimed to compare the agreement between CT pulmonary angiography (CTPA/CTV) and ultrasonography (US) for diagnosis of thromboembolic disease and determine the sensitivity, specificity, positive and negative predictive values of the 2 tests using the presence of thromboembolic disease as a reference standard.
Methods: 76 consecutive patients who were referred for CTPA at the Radiology department of Aga Khan University Hospital over an 8 month period between December 2008 and July 2009 were included in the study. All the patients underwent combined CTPA/CTV according to the usual departmental protocol. They subsequently had bilateral lower limb duplex US within 24 hours of the CTPA/CTV study. Results for the presence or absence of DVT were analyzed for both CTV and US. Presence of thromboembolic disease was defined by a composite reference standard and this was used to determine the sensitivity, specificity, positive and negative predictive values for both tests.
Results: 73 patients were included in the final analysis. The 2 imaging tests had similar results in 62 (84.93%) patients; CTV was positive and US was negative in 7 (9.6%) patients, while CTV was negative and US was positive in 4 (5.5%) patients. There was a moderate level of agreement (k= 0.528) between CTV and US for detection of DVT. CTV had a much higher sensitivity (94.1%), specificity (100%), PPV (100%), NPV (98.2%) compared to US (58.9%, 94.6%, 76.9%, 88.3% respectively) when the presence of thromboembolic disease was used as a reference standard.
Conclusion: CTV has higher sensitivity, specificity, positive and negative predictive values for detection of asymptomatic DVT compared to US when the presence of venous thromboembolic disease is used as a reference standard. Therefore, in patients suspected to have PE, CTV can be used to detect DVT without an additional duplex US examination.