مولانا سعید انصاری
افسوس ہے کہ گذشتہ مہینے ہمارے قدیم اور سابق رفیق مولانا سعید انصاری نے لاہور میں انتقال کیا، وہ دارالمصنفین کے دور اول کے رفقاء میں تھے، ان میں تالیف و تصنیف کا بہت اچھا سلیقہ تھا، اور وہ اردو زبان و ادب کا بڑا ستھرا مذاق رکھتے تھے، لیکن مزاج میں استقلال اور اعتدال و توازن نہ تھا، اس لئے کسی ایک مقام پر جم کر نہ رہ سکے، پہلی مرتبہ دارالمصنفین میں ان کا قیام سات آٹھ سال تک رہا، اس مدت میں انھوں نے سیر انصار اور سیر الصحابیات لکھی، اور امام ابو مسلم اصفہانی معتزلی کی تفسیر ’’جامع التاویل لمحکم التنزیل‘‘ جو اب دنیا سے ناپید ہوچکی ہے، اس کے اقتباسات امام رازی کی تفسیر کبیر سے جمع کرکے اس کو کتابی شکل میں مرتب کیا، جو اسی زمانہ میں دارالمصنفین سے شائع ہو گئی تھی، پھر دارالمصنفین چھوڑ کر صوفی پنڈی بہاء الدین کے یہاں چلے گئے اور اس کے لئے سیر الصحابہ کے نام سے شیخینؓ کے حالات ایک جلد میں لکھے، اس کے بعد مختلف اسکولوں میں ٹیچر رہے، مگر ان میں مستقل قیام نہ رہ سکا اس لئے حضرت سید صاحبؒ نے ان کو پھر دارالمصنفین بلالیا، اس مرتبہ ان کا قیام تین چار سال رہا، مگر متفرق مضامین کے علاوہ اس دور کی اور کوئی یادگار نہیں ہے، یہاں سے دوبارہ الگ ہونے کے بعد مختلف رسالوں کے اڈیٹر رہے، پھر سید صاحب نے ان کو ہندوستانی اکیڈمی الہ آباد کے سہ ماہی اردو رسالہ کا اڈیٹر مقرر کروایا، چند برسوں کے بعد اس سے بھی الگ ہوگئے، اور پاکستان قائم ہونے کے بعد لاہور چلے گئے، حضرت سید صاحبؒ نے ان کو لاہور یونیورسٹی کے شعبۂ اردو انسائیکلوپیڈیا میں رکھا دیا، اسی خدمت پرتھے کہ دفعتہ ان کے انتقال کی خبر ملی، شاعر...
Human cloning has emerged as a new and innovative technology in the reproductive and therapeutic science in the recent past. So far it has not been practiced over human beings but owing to its huge potential and possible scope, it has attracted the attention of not only the masses (particularly the infertile couples and LGBTQs etc) but the other stakeholders including the religious scholars from worlds’ prominent religions have given their views on this technology in order to guide their followers. This paper examines and reviews the religious points of view on human cloning. For this purpose, three Semitic religions in the world i-e Judaism, Christianity, and Islām have been examined. As far as Islam is concerned, this portion has been divided into two broad sections elaborating the Shī‘ah and Sunnī schools’ opinions. Being an innovative topic, the religious teachings do not address it directly hence the injunctions related to the reproduction are most relevant to it. Three Semitic religions have been examined from the perspective of admissibility or non-admissibility of human cloning, the rationale behind the verdict on human cloning and the possible solutions to the issues and problems faced by the followers in the case of acceptance or rejection of this biomedical technology. Most of the religions emphasize over adaptability of the natural mode of reproduction only, where male and female genders contribute to the reproductive cycle. The Semitic religions reject the reproductive cloning generally. The religious experts need to conduct more focused and updated research before coming to any conclusion about the permissibility or non-permissibility of this technique.
Biological sequence comparison is fundamental in extracting information that is valuable in applications such as protein structure prediction, predicting structural similarity, phylogenic analysis, homology detection, function prediction and discovering evolutionary relationship. Besides biologists, numerous researchers like mathematicians, statistician and even computer scientists attracted largely towards sequence analysis because of its involvement in various important applications. Protein classi cation is one of the major areas of research in recent years. Despite technological advances, classifying proteins accurately is still a big challenge. In this work, werst introduce an ant-inspired data mining approach for protein classi cation problem to investigate the e ectiveness of rulesbased approach. Supervised classi cation mechanism along with data mining concepts establishes compact and e cient rules classifying proteins into its correct family. Towards biological sequence analysis, we propose ASIF, a novel algorithm that consists of an alignment algorithm ASIFALIGN and a mathematical model (dASIF ) quantifying the sequence alignment. The proposed approach is based on intra-residue-distance and a plausible (unbiased) penalty factor. A standard dataset of DNA sequences are tested that produces reliable and robust sequence dissimilarities/similarities. Moreover, the proposed approach is used to construct a phylogenetic tree. Phylogenetic trees constructed by our approach outperform other methods. In addition, the proposed approach is applied to protein secondary structure classi cation problem. A dataset of twelve secondary structures are used to validate the distance matrix for classi cation purpose generated by the new alignment algorithm and a mathematical model. Results produced by the new scoring model are very much encouraging which shows reliability of our approach. Our approach not only provides a solid ground for its applications but also performs the fundamental job of dissimilarities/similarities calculation at a reasonable computational complexity. Results reveal the signi cance of our approach and provide a basis of the proposed model to be adopted for other biological applications such as protein function prediction, homology detection and protein fold recognition problem. I would like to dedicate this thesis to My Father (A strong and gentle soul who taught me to trust in ALLAH, believe in hard work and rest assure for the best of the results), My Mother (late)(For being myrst mentor and a true guide in shape of her beautiful memories and love), My Brothers, Sisters and Family (For supporting and encouraging throughout my studies and research).