Search or add a thesis

Advanced Search (Beta)
Home > Identification of Drug Targets by Investigating the Druggable Genome of Clinical Pathogen and Multi-Drug Resistant Bacteroides Fragilis

Identification of Drug Targets by Investigating the Druggable Genome of Clinical Pathogen and Multi-Drug Resistant Bacteroides Fragilis

Thesis Info

Author

Iqra Shahzadi

Department

National Center for Bioinformatics, QAU

Program

Mphil

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2015

Thesis Completion Status

Completed

Page

x,104

Subject

Bioinformatics

Language

English

Other

Call No: Diss / M.Phil / BIO /3987

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676716370851

Similar


Loading...
Loading...

Similar Books

Loading...

Similar Chapters

Loading...

Similar News

Loading...

Similar Articles

Loading...

Similar Article Headings

Loading...

مولانا احتشام الحسن کاندھلوی

مولانا احتشام الحسن کاندھلوی
مذہبی حلقہ کے لیے مولانا احتشام الحسن کاندھلوی کی وفات بھی بڑا حادثہ ہے، وہ اس دور کے صاحب تدین و تقویٰ عالم تھے، شیخ التبلیغ مولانا محمد الیاس رحمۃ اﷲ علیہ کے مجاز اور تبلیغی کاموں میں ان کے دست راست تھے، انھوں نے تبلیغ کو زندگی کا مقصد بنالیا تھا، ہر وقت اسی کی دھن رہتی تھی۔ انھوں نے بہت سے تبلیغی رسائل بھی لکھے، ان کی صحت عرصہ سے خراب تھی، اس کے علاوہ مختلف قسم کی مشکلات میں مبتلا رہے، لیکن کوئی معذوری تبلیغی کام میں حائل نہ ہوسکی اور مرض الموت تک اس کام کو انجام دیتے رہے، اﷲ تعالیٰ ان کے مدارج بلند فرمائے۔ (شاہ معین الدین ندوی، جنوری ۱۹۷۲ء)

Novel Bioactive Compound Production by Microbial Biota: Potential Antimicrobials Potential antimicrobials produced by microbial biota

Man is always trying to make his life easier and accomplished. He has faced mass destruction in history due to epidemics like small pox, malaria and plague. In order to combat diseases, exploration of man led him to search for causative agents and their control. A time reached when it was found that microbes are themselves a source of potent metabolites which have proved to be effective as drugs and medicines showing great antibiotic activity. It is necessary to find out new sources for potential new antimicrobial compounds. Several hundred important compounds have been isolated which have antibiotic activities and diverse chemical nature. But these compounds should have minimum toxicity to be useful clinically. Because of the increasing resistance of pathogens, there was a never ending desire and need to search for more. Bioactive Compounds have been extracted from microbes which are produced as secondary metabolites. Day by day, new compounds are being discovered giving a hope of golden future of drug industry. The current article emphasizes the importance and need to search for new bioactive compoundsto overcome infections caused by multiple drug resistant (MDR) and biofilm forming pathogens irrespective of the previously present knowledge. 

Evaluating the Role of Seed Size and Enhancements in Improving Wheat Productivity under Different Rice Wheat Systems

Rice-wheat cropping system is the most exhaustive cereals production system and hasseveral issues asdelayed wheatsowing, residue management and uniformstand establishment. Therefore, this study was conducted to develop low input, zero tillage wheat sowing technology for residues management in rice-wheat cropping system with better seedling emergence through two independent field experiments. In the first experiment, the potential role of seed size and seed enhancements in improving wheat productivity planted by conventional and conservation methods was evaluated. In the second experiment, influence of seed size in improving the productivity of wheat in conventional and conservation rice system was evaluated. Rice was either raised in conventional anaerobic (puddled + flooding) ordirect seeded aerobic system (DSR), and after rice harvest, wheat was planted following conventional method, Happy seeder and Turbo seeder using wheat cultivars with bold, medium and smallsized seeds used in experiment was tested. Both experiments werelaid out in randomized complete block design with split-split plot arrangement.Wheat sowing methods andrice production systems werekept in main plots in both studies respectively, while seed size (first experiment)and wheat sowing method (second experiment) was randomized in sub-plots;seed priming techniques and different seed size was placed in sub–sub plots in first and second study respectively. In the first experiment, wheat planted with conservation tillage using Happy seeder improved thegrain yield and yield related traits. Seed priming significantly improved the stand establishment. Bold seed had better stand establishment, yield related traits and grain yield of wheat than smaller and medium grains. Crop sown with Happy seeder using hydroprimed seedscompleted maturity earlier through rapid Phenologicaldevelopments. In second experiment,rice production systems did not improve all recorded traits; however,better establishment stand was observed in wheat sown afterconventional rice culture while poor seedling emergence was recorded for the wheat sown after DSR. Among different sowing methods of wheat, the happy seeded planted wheat had better performance. Different seed size influenced allagronomic traits; however,the cultivar with medium sized seeds (FSD-2008) gave higher yield than bold and small seededvarieties.The economic analysis showed that maximum net income and benefit cost ratio werewhen bold seeded (AS-2011) wheat cultivar was planted using happy seeder following DSAR. In conclusion, zero tillage wheat and aerobic rice culture were best resource conservation technologies, whichimproved the performance and productivity of rice-wheat cropping system