اکرامؔ سانبوی (۱۹۴۲ء۔۲۰۱۱ء) کا اصل نام محمد اکرام ہے۔ آپ ریاست جموں کشمیر کے سرمائی صدر مقام جموں میں پیدا ہوئے۔ آباؤ اجداد کا تعلق ضلع جموں کی تحصل سانبہ سے تھا۔ اسی لیے اکرام سانبوی کہلاتے تھے۔ قیام پاکستان کے بعد جموں سے ہجرت کر کے سیالکوٹ کے محلہ پورن نگر میں آباد ہوئے۔ آپ نے ایم ۔اے اردو اورنیٹل کالج لاہور سے کیا اور اس کے بعد جناح اسلامیہ کالج سیالکوٹ میں اردو کے لیکچرا ر کی حیثیت سے آپ کا تقرر ہوگیا۔(۹۸۷)
اکرام ؔغزل اور نظم کے شاعر ہیں۔ کالج کے زمانے میں انھوں نے کئی مزاحیہ مضامین اور افسانے لکھے جو کالج میگزین کے علاوہ کئی سطح کے ادبوں رسالوں میں شائع ہوئے۔ تنقیدی مضامین اور خصوصاً شاعری کا شوق بڑی عمر میں ہوا۔ اس لحاظ سے ان کی شاعری کی عمر کچھ زیادہ نہیں تاہم ان کے کلام سے ظاہر ہوتا ہے کہ ان میں ایک اچھا شاعر بننے کی پوری صلاحیت ہے۔ اکرامؔ کے کلام میں ہمیں گہرا سماجی شعور ملتاہے۔انھوں نے بڑی خوبصورتی سے اپنی شاعری میں اپنے ماحول کی شعری زبان میں عکاسی کی ہے ۔اور اس کے ساتھ ساتھ اپنے وقت کے مسائل کو بھی بڑی عمدگی سے پیش کیا ہے۔ ان کے ہاں ہمیں افسردگی اور بے چینی نظر آتی ہے۔ جو ان کے دل کی دنیا کی بھر پور عکاسی کرتی ہے:
ہر طرف یاس کا اندھیرا ہے
/زندگی ہو گی اب بسر کیسے
-بے ثمر ہو گئے شجر کیسے
-بے صدا ہو گئے نگر کیسے
(۹۸۸)
زبان شعر...
Najeeb Al-Kailani is a famous Egyptian Islamic writer. He was immensely impressed by Iqbal’s philosophy. He was absorbed in the study of Islamic literature in the early days of his life and dared to write many articles in various magazines, touching various aspects of Iqbal’s poetry. Al-Kailani then by maintaining his interest in Iqbal’s poetry, was compelled to write the book entitled إقبال الشاعر الثائر"”, (Iqbal, the Revolutionary poet). He was awarded with prize by ministry of education and training, and in 1977 President of Pakistan General Muhammad Ziaul haq awarded him gold medal. This article highlighted the impact of Allama Muhammad Iqbal in al-Kailani’ book and analyzed its text by refereeing it to the original poetry of Allama Muhammad Iqbal. This article concluded that Kailani’s book is finest and comprehensive book, which demonstrated the life and philosophy of Allama Muhammad Iqbal.
The work reported here deals with the bio-assay guided isolation of secondary metabolites from Cestrum nocturnum (leaves) and Cestrum diurnum (leaves and berries). First part of the dissertation deals with the biological activities of different parts of the selected plants while second part describes the purification and characterization of the isolated constituents. Shade dried plant material was extracted with methanol. The concentrated methanolic extract was fractionated with n-hexane, chloroform, ethyl acetate and iso-butanol and extractive values determined. All the collected extracts were screened for anti-bacterial, anti-fungal, anti-oxidant and anti-leishmanial activities. The anti-oxidant experiment was also conducted with all the parts. Crude extract of aerial part of C. nocturnum displayed 57 % antioxidant activity while one of its isolated fractions (ethyl acetate) displayed a maximum of 67 % antioxidant activity. Similarly, the crude extract of aerial parts of CD i.e., aerial part without fruit, green fruit, ripe fruit, exhibited 86, 81 and 90 % antioxidant activities respectively. The hexane fraction of CD green fruit showed higher antioxidant potential (87 %) than its crude methanolic extract. Due to our interest in saponins for further studies, they were selectively isolated and processed in the same way for antioxidant activities in crude form from both the plants. The highest antioxidant activity was found with the CD ripe fruit CS extract (90 %) while the least one was with both the aerial parts of the two plants (approx. 80 %). The results obtained with nine microbial strains were moderate. S. typhii was the most resistant strain. On the average gram positive bacteria showed good zone of inhibition with Cestrum diurnum. Gram negative strains showed good results mostly with Cestrum nocturnum. The crude saponins extracts of berries were the most active giving zone of inhibition in the range of 8.5-15mm. Incredible anti-leishmanial activities are being reported for the selected plants. All the plant extracts exhibited hundred percent inhibition of the leishmania parasite. Second part of the thesis deals with the isolation and purification of the secondary metabolites of C. nocturnum and C. diurnum. Hum-V isolated from C. nocturnum was characterised using different spectroscopic techniques as (25R)- spirost-5ene-2,3-diol, [2α, 3β] 3-O-{β-Dglucopyranosyl (1→4)-β-D-glucopyranosyl (1→2)-β-D-glucopyranosyl{(1→4)-β-Dxylopyranosyl] (1→4)-β-D-galactopyranoside). It was reported as nocturnoside A. Another reported compound was also purified and characterized as karatavoiside A, spirost-5-ene-2,3-diol [2α, 3β,25R], 3-O- [β-D-glucopyranosyl(1→2)] {-β-Dxylopyranosyl( 1→3)-β-D-glucopyranosyl(1→4)}-β-D-galactopyranoside. A new compound isolated from the same specie, elucidated as 3-O-β-D-xylopyranoside-olean- 12-en-28-oic acid-28-O-β-arabinopyranosyl-(1-3)-β-D-galactopyranosyl-(1-2)- β-Lglucopyranosyl-( 1-4)- β-L-glgucopyranosyl ester.