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Home > Studies on Therapeutic Effects of Spindus Mukorossi Gaertn. Bark Extracts and Protective Aptitude Against Cci4 Induced Renal and Adrenal Toxicity in Rat

Studies on Therapeutic Effects of Spindus Mukorossi Gaertn. Bark Extracts and Protective Aptitude Against Cci4 Induced Renal and Adrenal Toxicity in Rat

Thesis Info

Author

Madeha Shah

Department

Department of Biochemistry, QAU

Program

Mphil

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2017

Thesis Completion Status

Completed

Page

ix,95

Subject

Biochemistry

Language

English

Other

Call No: Diss / M. Phil / BIO / 4753

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676716757786

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ستاروں سے آگے جہاں اور بھی ہیں

ستاروں سے آگے جہاں اور بھی ہیں
نحمدہ ونصلی علی رسولہ الکریم امّا بعد فاعوذ بااللہ من الشیطن الرجیم
بسم اللہ الرحمن الرحیم
معزز اسا تذہ کرام اور میرے ہم مکتب شاہینو!
آج مجھے جس موضوع پر اظہار خیال کرناہے وہ ہے: ’’ستاروں سے آگے جہاں اور بھی ہیں‘‘
جنابِ صدر!
شاعراس شعر میں ہماری توجہ جہد مسلسل کی طرف دلانا چاہتا ہے، وہ کاہلی، سستی اور تساہل کے قعرِ ذلت میں گرنے سے بچاتا ہے ،وہ یہ یاد کرانا چاہتا ہے کہ حرکت میں برکت ہے اور ہمیشہ کی کدو کاوش سے انسان بالآ خرمنزل پرپہنچ جاتا ہے۔
صدرِمحترم!
زندگی حرکت کا نام ہے۔ حیات کے لمحات متحرک رہنے والے کے ہوتے ہیں،لمحات زیست کی چاشنی جمود کا شکار افراد کے لیے سمِ قاتل ہے۔ زندگی کی رنگینیاں، زندگی کی رعنائیاں اسی کوملتی ہیں جو ان کے حصول کے لیے جسمانی اور فکری قویٰ منظر عام پرلاتا ہے اس طرح وہ نہ صرف ستاروں کو دیکھتا ہے بلکہ ستاروں پر کمندیں بھی ڈال لیتا ہے اور کامرانی اس کے قدم چوم لیتی ہے۔
جنابِ صدر!
انسان اگر آگے بڑھنے کا جذبہ بیدار رکھے گا، تو آسانیاں میسر آتی جائیں گی، مشکلیں حل ہوتی جائیں گی ، پریشانیوں کا وجود عنقا ہو جائے گا ، مشکلات، سہولیات میں بدل جائیں گی ، الجھنیں کافور ہو جائیں گی ، خوشیوں اور مسرتوںکے گلستانوں میں بہار آجائے گی۔
صدرِ محترم!
جمود انسان کے لیے سم قاتل ہے، جمود اشیاء خوردنی میں آجائے تو انہیں متعفن کر کے رکھ دیتا ہے۔ اعضائے جسمانی میں آجائے تو انہیں شل کر کے رکھ دیتا ہے علم و دانش میں آجائے تو فصاحت، جہالت کے قریب ہو جاتی ہے۔ جمودمطالعہ میں آجائے توصاحب علم کی میز گردآلود ہو جاتی ہے۔
صدرِمحترم!
انسان کی ترقی کا راز...

Image of Islam Western Media: An Overview of Studies About Portrayal of Islam and Islamic World 1971-2001

ABSTRACT: This article presents an over view of studies conducted by the various scholars about portrayal of Islam and Islamic world during the time period (1971-2001) . It is claimed that mainstream media of west and US have been disseminating false information about Islamic world since the several decades. Due to the distorted images, developed and manipulated by the media, Islam is the name of negativity in the west. It is generally believed that western and United States mainstream media often misrepresents and inaccurately interprets/portrays Islam, Islamic world and its manifestation. After conducting in depth analysis of various studies regarding portrayal of Islamic world prior the incident of 9/11, it was found that elite media in the United States including the newspapers: Like New York Times and Washington post; the magazines: like Time and News Week, electronic media including: like ABC, CBS, NBS & CNN have been highlighting Islamic world in negative and unfavorable manner. It is said this anti Islamic campaign has reached to enormous proportion with the demise of communism. The that negative image of Islamic country is primarily a conspiracy of American foreign office to invent a new bogy and enemy to fill vacuum created by the collapse of soviet Union and world wide desperation of communism, particularly demise of communism in former USSR

Green Approach Towards the Synthesis of Schiff Bases and Synthesis of Nanoparticles of Different Metals by Various Methods

This dissertation has been divided into three chapters. Each chapter has its own references. The chapter 1 describes synthesis, characterization and bioassay screening of sixtytwo (62) Schiff bases of different aldehydes (ᵴƀ1-ᵴƀ55) and ciprofloxacin (cp1-cp7) with primary amines by both, conventional as well as ultrasonication methods. Thirteen Schiff bases (ᵴƀ6, ᵴƀ11, ᵴƀ17, ᵴƀ22, ᵴƀ23, ᵴƀ24, ᵴƀ28, ᵴƀ29, ϲρ3, ϲρ4, ϲρ5, ϲρ6 and ϲρ7) are new derivatives. Comparative analysis of these two methods was also carried out. The structures of all synthesized compounds were determined with the help of IR, 1H-NMR, 13C-NMR and EI-MS spectroscopy techniques. All synthesized compounds subjected to different biological activities such as Antiinflammatory activity, Insecticidal activity, Urease Inhibitory Activity, Tyrosinase Inhibitory Activity, Anti-bacterial activity, Anti-fungal activity and Anti-oxidant activity. Only eight compounds showed tyrosinase inhibitory activity in which four compounds ᵴƀ33, ᵴƀ49, ᵴƀ50 and ᵴƀ51 were found most active and the rest of four compounds ᵴƀ32, ᵴƀ34, ᵴƀ38 and ᵴƀ55 were moderately active. ϲρ is active against tyrosinase enzyme but its derivative ϲρ6 was more active. Total eight compounds were found active in urease inhibitory assay. Five compounds ᵴƀ35, ᵴƀ38, ᵴƀ41, ᵴƀ52 and ᵴƀ54 exhibited good activity and rest of three ᵴƀ33, ᵴƀ37 and ᵴƀ49 were moderately active. ϲρ and its derivative ϲρ1 and ϲρ2 were also active in urease inhibitory assay. The compounds ᵴƀ1, ᵴƀ13, ᵴƀ41 and ᵴƀ49 were found significantly active against nearly all applied bacterial strains, ϲρ and its all derivatives (ϲρ1-ϲρ7) are active against many bacterial strains. It is found that Compounds ᵴƀ1 and ᵴƀ2, ᵴƀ13, ᵴƀ38, ᵴƀ40 to ᵴƀ43 showed strong activity against various fungal strains. The synthesized compounds were also tested for anti-oxidant activity. They displayed varying % inhibition, among them ᵴƀ3, ᵴƀ6, ᵴƀ11, ᵴƀ22, ᵴƀ24, ᵴƀ29, ᵴƀ30, ᵴƀ37, ᵴƀ38, ᵴƀ43, ᵴƀ48 and ᵴƀ52 exhibited remarkable anti-oxidant activity. ϲρ, ϲρ1 and ϲρ6 also displayed anti-oxidant activity. ϲρ6 exhibited insecticidal and immunomodulatory/anti-inflammatory activity while Unfortunately, all candidates were found inactive towards both activities. The chapter 2 describes Synthesis of nanoparticles of different metals by various methods. Three types of nanoparticles were synthesized, metal, metal oxide and metal ferrite. Metal nanoparticles were synthesized by Chemical Reduction Method, (Green synthesis) by consuming Cucumis sativus, Azadirachta indica and Syzygium aromaticum aqueous extract and egg white as a source of albumin. Metal nanoparticles of Fe (INP), Ni (NNP), Cu (CNP), Zn (ZNP), Pb (LNP), Mg (MNP) and Co (CTNP) were synthesized. For the synthesis of metal ferrite Co-precipitation technique was employed, by this method CuFe2O4 (CFNP), NiFe2O4 (NFNP), CoFe2O4 (CTFNP), PbFe2O4 (LFNP), and MgFe2O4 (MFNP) nanoparticles were synthesized. For metal oxide nanoparticles Sol-Gel Synthesis (using tartaric acid as Complexing agent), Sonochemical synthesis by using Camellia sinensis extracts and by using seaweeds (Hypnea musciformis, Gracilaria, Laurencia pinnatifida and Enteromorpha intestinalis). These seaweeds were first time used to synthesize different metal nanoparticles along with sound waves. Fe3O4 (IONP), NiO (NONP), CuO (CONP), ZnO (ZONP), MgO (MONP) and PbO (LONP) metal oxides nanoparticles were prepared. UV-vis, FTIR, SEM, AFM, EDX and XRD were the characterization techniques used to confirm the synthesis, attachment of capping agent, morphology and size determination. These nanoparticles were employed to check their anti-microbial activity. These nanoparticles were also used with anti-aging / anti-bacterial cream to investigate antimicrobial and anti-oxidant activity. Some nanoparticles were also used to remove lead ion from aqueous solution by Adsorption. Chapter 3 deals about overview of biological activities and all the procedures used to find the inhibitory power of all synthesized products.