ذکر میرا وہ کریں منظور کیوں
جانے وہ الفت سے ہیں معذور کیوں
پوچھتی ہے تم سے یہ میری وفا
جان کر مجھ سے ہوئے رنجور کیوں
آن بیٹھے وہ نظر کے سامنے
قبلہ و کعبہ ہو اب منظور کیوں
ہیں میسر ان کی مست آنکھیں جنھیں
وہ اٹھائیں بادہ و انگور کیوں
تم فضاؔ جب ہو مری محبوب تو
پھر میں دیکھوں حسن کیا اور حور کیوں
Background: Chronic hepatitis C infection has created a huge burden of disease causing serious health effects. The combination therapy used to treat hepatitis C virus (HCV) infection includes Pegylated interferon and Ribavirin. As cholesterol biosynthesis plays a pivotal role in HCV replication, the use of various statins has been associated with higher sustained viral response Objective: To compare the efficacy of atorvastatin plus pegylated interferon and ribavirin versus pegylated interferon and ribavirin alone in patients of chronic hepatitis C with genotype-3a Methods: This Randomized controlled trial was conducted at outpatient department, Mayo Hospital Lahore for six months i.e. May to November 2017. After ethical approval, 60patients of ages 25 to 55 years of either gender with chronic hepatitis C with genotype 3a were included in the study. Informed consent was taken from all patients. Then patients were randomly allocated into two groups “A” and “B” using random number table. Patients in Group A received standard of care treatment for chronic hepatitis C i.e. Pegylated interferon and ribavirin while the patients in Group B also received tab atorvastatin along with the standard treatment. Patients were follow up for 4 week. Blood samples were collected and HCV RNA detection. All this information were entered in proformaResults: In standard therapy group, the mean age of patients was 39.50±8.39years. In atorvastatin plus standard therapy group, the mean age of patients was 34.30±6.78years. In standard therapy group, there were 25 (83.3%) males and 5 (16.7%) females. In atorvastatin plus standard therapy group, there were 16 (53.3%) males and 14 (46.7%) females. After 4 weeks, Rapid VirologicalResponse (RVR) was achieved in 4 (13.3%) patients in standard therapy group while in 14 (46.7%) in atorvastatin plus standard therapy group. The difference was significant (p<0.05) Conclusions: Atorvastatin in combination with Pegylated interferon and ribavirin have better efficacy as compared toPegylated interferon & ribavirin alone in chronic hepatitis C-3a.
Teaching and learning mathematics is considered a boring and difficult task by the teachers as well as students where teachers have to take whole responsibility of transferring mathematics knowledge to students and students fearfully receive this knowledge as passive recipients. My experiences a learner and later as a teacher in the same situation has stimulated my thinking about a better and effective way of teaching and learning mathematics which could invite students' active participation in their own learning. Hence I took the opportunity to conduct a study according to my interest in mathematics teaching. The focus of my study was the implementation of the Do - Talk - Record strategy in lower secondary mathematics' class in a government school. The research was carried out for five weeks and the study was designed to follow three stages (pre-intervention, intervention and post-intervention). I followed a qualitative research design because qualitative research seeks to enlarge our sense of explanation and makes things understandable by means of explanation or interpretation. The observation of classroom practice, interview of research participants and my own teaching helped me with data collection. During the pre-intervention stage, I found that the teacher's current emphasis was on rote learning. Students blindly followed the procedure directed by the teacher. The purpose of my study was to create an environment for the students in which they became self learners and, they would relate mathematics to their daily life with anintent to promote long-term memory. Through the Do - Talk - Record strategy I tried to develop discussion skills in students. For that purpose I gave students some activities. During activities I recognised some teaching approaches which helped me to know how students learn; such as learning through misconception, learning through prior knowledge, learning by doing, learning by questioning and learning through discussion. I used those approaches which enabled me to support students' conceptual understanding of fraction'. The result of this approach enabled me to suggest some recommendations, like the Do - Talk - Record strategy be introduced in the educational institutions in Pakistan on a trial basis.