نواب مقصود جنگ مولاناحکیم مقصود علی خاں
اسی طرح کادوسرا حادثہ نواب مقصود جنگ مولانا حکیم مقصود علی خاں صاحب کاپیش آیا۔ مرحوم ایک طبیبِ حاذق، ممتاز عالمِ دین اور بہترین خطیب و مقرّرتھے۔زندگی کابڑا حصّہ حیدرآباد میں بسر کیااورکوئی شبہ نہیں کہ بڑی شان سے بسر کیا۔ ہوش مندی، معاملہ فہمی، صاف گوئی،جرأتِ حق اورپاسِ وضع میں اپنا جواب نہیں رکھتے تھے۔نظام دکن کے طبیبِ خصوصی اورمصاحبِ خاص ہونے کے باوجود حیدرآباد کی عوامی زندگی میں بھی پوری طرح دخیل تھے،ہراجتماعی کام میں بڑھ چڑھ کرحصّہ لیتے تھے اور ہرطبقے میں اُن کی رائے کاوزن محسوس کیاجاتا تھا یہی وجہ ہے کہ ریاست کے ختم ہونے کے بعد بھی اُن کے مقامِ عظمت میں کوئی فرق نہیں آیاتھا۔عمر بھر طبِ یونانی کی بے لوث خدمت کرتے رہے، جہاں تک فن کاتعلق ہے سچ تویہ ہے ان کی سرگرمیوں سے اس فن کے تنِ بے جان میں روحِ تازہ آگئی تھی، حیدرآباد کاطبیّہ کالج اور انجمن اسلامیہ اُن کی زندگی کے شاندار تعمیری کارنامے ہیں اور جب تک یہ ادارے قائم ہیں اُن کے جذبۂ خدمتِ خلق پرگواہی دیتے رہیں گے۔ ’’دارالعلوم دیوبند‘‘ ’’جمعیۃ علماء ہند‘‘ اور ’’ندوۃ المصنفین‘‘سے بھی ربطِ خاص رکھتے تھے۔ پیرانہ سالی ،ضعیفی اور معذوری کے باوجود طویل سفر کی صعوبتیں برداشت کرتے تھے اور دارالعلوم کی مجلسِ شوریٰ کی کارروائیوں میں جوانوں کی طرح حصّہ لیتے تھے اوراُن کے تجربے ،خلوص اور حُسنِ تدبّر سے بہت سے نازک اور اُلجھے ہوئے مسئلوں میں مدد ملتی تھی۔
۱۹۵۰ء میں حیدرآباد میں جمعیۃ علماء ہند کاجو تاریخی اجلاس ہواتھا اس کی کامیابی مرحوم ہی کی جدّوجہد اوراثر ورسوخ کی رہینِ منّت تھی،صدر استقبالیہ کی حیثیت سے مرحوم نے اس اجتماع میں جو خطبہ پڑھا تھااُس سے ان کے علمی پایہ اور سیاسی بصیرت کابخوبی اندازہ ہوسکتا ہے۔
راسخ العقیدۃقدیم عالم دین ہونے کے باوجود...
خطۂ بہاول پور کے چند مغربی اسفار(ایک نو آبادیاتی باشندے کی نظر میں) Where the western colonial powers have had a profound influence on other forms of literature, such a genre of travel journalism in the Bahawalpur region could not be safeguarded. The region is known for its civilization and culture, yet the rumors that have been written from Pakistan to Pakistan remain mournful that the tradition under the influence has stirred. Although the nature of the journals being written in the Bahawalpur region varied, the correspondents here discussed the impact that the west had given them. At the national level, the ambassadors sought for western couples and also showed an attitude of disregarding civilization and culture. At the national level, the ambassadors sought for western couples and also showed an attitude of disregarding civilization and culture. Travelling entrepreneurs separate from their country apart from a new angle and independent thinking, they seem to be lacking in the west. This difference can be seen even more clearly if domestic and international travels are taken into account.
The idea of starting this research project was to elucidate the development procedure of a novel biocompatible nano composite that is directly linked to the properties of natural bone in terms of its composition, morphology, mechanical properties and biocompatibility. These nanocomposites are composed of hydroxyapatite (HA) and whitlockite (WH) nanoparticles embedded in polymeric matrix and hydrogels.The fabrication procedures used are of common use including pre-treatment of nanoparticles and embedding into biopolymers such as Cyclic olefenic copolymer and CollagenPEGDMA hybrid matrix where effect of different loading ratios of HA nanoparticles and WH nanoparticles was investigated.Nano powders of HA were chemically synthesized under various processing conditions using surfactants with different charges and chain lengths such as CTAB (cationic) and SDS (anionic) surfactants were used in the synthesis procedures for regulating the nucleation and growth of the hydroxyapatite phase. The synthesis methods, mainly based on aqueous systems were used which are simple and can offer accurate control on the nano powders of various size and morphologies. The effect of different weight ratios ofHA nanoparticles and WH was evaluated after successful fabrication of nanocomposites by dispersing these nanoparticles in polymeric matrices. TOPAS/HA, TOPAS/WH and Collagen-PEGDMA/HA nanocomposites were successfully prepared and further characterized. Solution casting procedure was used to construct these nano composites. Effect of various weight ratios was investigated on physical, chemical and mechanical properties of the nano composites. These nano composites were characterized through Scanning Electron Microscopy, Fourier Transform Infrared Spectroscopy, Compression testing, Biocompatibility testing including cell culture of bone/cartilage cell lines, antibacterial test, biodegradability, and swelling characteristics. The morphology of nanocomposites has been investigated using Scanning electron microscopy and Atomic force microscopy. Compression testingwas performed on all type of nanocomposites to evaluate and optimize the mechanical strength. Cell culture wasperformedto evaluate thebiocompatibility ofthese nanocomposites onbone cell lines in case of TOPAS/HA and TOPAS/WH while cartilage cell lines were used in the case of COl-PGD/HA nanocomposites. Swelling and degradation characteristics were also evaluated. It was revealed from this study thet the compressive strengths of nano compositescan be enhancedwith the addition of nanoparticlesand optimized to make values comparable with the compressive strength of natural bone and cartilage tissues. In case of TOPAS/HA the increased values are185 % from 0.26 to 0.74 MPa at the concentration of 10 wt%.Whearas in case of PGD-16/HA, up to 10 wt%, strength is enhanced ~ 90 % from 9 to 17.3 kPa.In case of TOPAS/WH increase of 0.2MPa to 1.7MPa in strength at lower concentration of WH upto 10wt%has been experimented. The biocompatibility data of cell viability on the whole, is above 90% in all nanocomposites and the values are even higher than95%.In TOPAS/HA (10 wt%) exhibits the highest trend for cell viability of 99.9 ± , while in case of PGD-16/HA (10 wt%) the cell viability of hybrid composites is 100 % as comparedto the TCP control group while the cell viability values are around 95-100% in case of TOPAS/WH (10wt%). These results make these nanocomposites suitable for biomedical applications.