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Us Drone Stokes Policy in Pakistan:

Thesis Info

Author

Muhammmad Noman

Supervisor

Noman Omar Sattar

Department

Department of Area Study, QAU

Program

Mphil

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2015

Thesis Completion Status

Completed

Page

62

Subject

Area Study

Language

English

Other

Call No: DISS / M.PHIL / A.SC / 241

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676717488747

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حرفے چند

عصر حاضر میں موسمیاتی تبدیلی بین الاقوامی مسئلہ بن چکا ہے۔ انٹرنیشنل کلائمیٹ چینج پینل کی تازہ ترین رپورٹ بتاتی ہے کہ اس وقت ماحولیاتی تبدیلیاں پوری دنیا کو بری طرح متاثر کر رہی ہیں۔ عالمی موسمیاتی تبدیلیوں سے متاثر ہ ممالک میں پاکستان  بھی شامل ہے۔سیلاب 2022ء موسمی تبدیلی کے  اثرات کا منہ بولتا ثبوت ہے۔ افسوسناک بات یہ ہے کہ پاکستان میں سیاسی و معاشی بحران کی وجہ موسمیاتی تبدیلی کے خوفناک اثرات کا مسئلہ پس پردہ چلا گیا ہے۔ مسئلہ حقائق کا نہیں بلکہ اقدامات اٹھانے کا ہے۔موسمیاتی تبدیلیوں کے اثرات کو انفرادی اور اجتماعی طور پر روکنے کے ہنگامی بنیادوں پر اقدامات اٹھانے کی ضرورت ہے۔پرنٹ،الیکٹرانک اور سوشل میڈیا کی مدد سے ماحولیاتی مسائل (موسمیاتی تبدیلی،گلوبل وارمنگ،ماحولیاتی آلودگی ) کو اجاگر کرنا چاہئے۔یہ ایک خالصتاً انسانی و قومی مسئلہ ہے۔

قدرتی وسائل کا غیر دانشمندانہ استعمال ہی موسمیاتی  تبدیلیوں کا باعث بنتا ہے۔ان موسمیاتی تبدیلیوں پر قابو پانا حضرت انسان کے لئے ایک چیلنج  بن چکا ہے۔اس کے لئے اقوام متحدہ کے زیرنگرانی  کوپ (COP)کے نام سے ماحولیاتی کانفرنسز منعقد کی جاتی ہیں۔ اس وقت ماحولیات کے بارے میں آگاہی پیداکرنا قومی فریضہ ہے۔ میرے عزیز ترین شاگرد ڈاکٹر عبدالمنان چیمہ نے " قدرتی وسائل اور ان کا استعمال: اسلامی اور سائنسی علوم کے تناظر میں " کے موضوع پر قلم اٹھا کر ایک قومی خدمت سرانجام دی ہے۔ڈاکٹر چیمہ نے اس کتاب میں قدرتی وسائل اورماحولیاتی تحفظ کے اسلامی اصول و آداب پیش کئے ہیں۔ پیش نظر کتاب ڈاکٹر چیمہ کی تحقیقی بصیرت کی آئینہ دار ہے۔امید ہے کتاب " قدرتی وسائل اور ان کا استعمال: اسلامی اور سائنسی علوم کے تناظر میں " کا مطالعہ قارئین کے لئے مفید و نافع ثابت ہوگا۔

 ڈاکٹر فرحت نسیم علوی

پوسٹ ڈاکٹریٹ...

Impact of Traditional Values on the Equality of Females Living in Balochistan, Pakistan

Societies follow a traditional value. Traditions evolve and are adapted according to the wish of majority of the people. Cultures mostly are under the disposition of the patriarchal system, a system dominated by men, where women are discriminated and subjugated because they hold a vulnerable position in the society. The present study focuses on equality of women present in Quetta Balochistan, effected by the cultural values present. Data was selected from seven Government Girls degree Colleges of Quetta based on random sampling method. The researcher used SSPS tool to evaluate the data. Results highlighted that cultural values are affecting the females here in Quetta and they are not treated as equals to their male counterparts.

Study on Pharmacology and Toxicology of Carissa Carandas Auct. and Herbal Products Used in Cardiovascular Diseases

BACKGROUND OF RESEARCH: Herbal medicines have been used for thousands of years. The practice continues today because of its biomedical benefits and place in cultural believes in many parts of the world. The economic reality of the inaccessibility of modern medications for many societies has also played a major role in the broad use of herbal medicines. The World Health Organization has recognized the contribution and value of the herbal medicines used by a large segment of world’s population. A growing interest in usage has created the need for greater precision in preparation and evaluation and has stimulated research into herbal medicines’ various uses and applications. AIMS OF RESEARCH: This study was carried out on the pharmacological and toxicological screening of ethanol: water (1:1) extract of leaves of Carissa carandas (Auct.) and a Poly Herbal Product Mufarreh Yaqooti Motadil (Hamdard Laboratories (Waqf.) Pakistan), and comparative study of these with allopathic medicines. This Herbal product also contains extracts from animal and mineral origin. It has been used traditionally for the treatment of different cardiovascular disorders particularly it has cardio tonic property. But the use was not having any scientific evidences or data for the mechanism of action to prove its efficacy and safety. RESEARCH METHADOLOGY: In this effort we planned to evaluate the In vivo and In vitro the pharmacodynamic study of this drug on different cardiovascular parameters. Another Aquous:Ethanol (1:1) extract of Carissa Carandas leaves was also used for screening and following parameters were studied in different doses by precise methods: i. Effect of tested samples on Blood pressure using invasive method of I.V. cannulation on Sprague Dawley Rats, using four channel Recorder. ii. Comparative study with the synthetic drugs for hypotensive effect. iii. Determination of mechanism of action for Hypotensive activity. XIII iv. Diuretic activity of the tested materials on healthy male and female Sprague Dawley rats. v. Comparison of the diuretic effect with the conventionally used allopathic medicine, Furosemide. vi. Effect of the tested samples on different Cardiac parameters using Intact Heart, model of Frogs (Rana cyanophlictis). vii. Determination of mechanism of action for cardiac activity. viii. Comparison of these cardiac parameters with Digoxin using Intact Heart model of Frog. ix. Cardiac activity of tested samples by invasive method of Langendorf’s Assembly of Isolated Heart, using heart models of Rabbits (Oryctolagus cunniculus). x. Antihyperlipidaemic Activity of the tested samples on rats by the method of histopathological study of organs like Heart, Liver, Kidney and Spleen for structural changes xi. Biochemical screening of serum for different chemicals like Cholesterol, HDL, LDL, Total Protein, Creatinine Uric acid etc., and enzymes like ALAT, ASAT, Alkaline Phosphatase, etc., for functional changes of the organs in these models. xii. Toxicological studies of the tested samples for the Safety Evaluation of these herbal products after Acute (for determination of LD50), Sub acute and Chronic use of drugs in NMRI Mice and Sprague Dawley Rats. xiii. Histopathological and Biochemical Screening for structural and functional changes respectively, in Rat models for safety evaluation. FINDINGS AND CONCLUSION: The Drug and extract has shown very significant results for pharmacological activity on cardio vascular system.The toxicological studies of the extract and drug on treated animals showed that, they are very safe in acute treatment even with a very high dose i.e., 5000mg/kg which did not show any mortality. The high dose was also used for Sub acute and chronic toxicity testing and was found to have no toxic effects except some adverse effects on liver, spleen and kidneys, only by Chronic administration of Carisssa carandas leaves extract in very high dose, as demonstrated by Biochemical and Histopathological evaluations. Other Poly Herbal Drug Product did not show any toxic effects. It is suggested that further studies for the Pharmaceutical preparation of a product form this extract should be performed in doses less than 5000mg/kg. That will help to introduce a potent, safe and cost effective drug for our people suffering from cardiovascular disorders