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Genetic Mapping of Hearing Impairment Genes

Thesis Info

Author

Naveeda

Department

Deptt. of Biochemistry, QAU.

Program

Mphil

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2007

Thesis Completion Status

Completed

Page

xvii,126

Subject

Biochemistry

Language

English

Other

Call No: DISS/M.Phil BIO/1867

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676717716994

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ڈاکٹر الکزنڈر کرم برون

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            اڈنبرا یونیورسٹی کے مشہور ماہر کیمیات ڈاکٹر الکزنڈر کرم برون کا ۸۵ سال کی عمر میں ا نتقال ہوا۔ انھوں نے تقریباً ۵۰ سال تک یونیورسٹی میں خدمات انجام دی تھیں اور تمام دنیا میں اپنے فن کے مستند استاد تسلیم کیے جاتے تھے۔ (جنوری ۱۹۲۳ء)

 

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The ultimate goal of an education system is to produce a better citizen and create a better society. In this regard, it is the responsibility of state to design its education system on sound grounds. In Pakistan, there is dual education system, modern education system and traditional Madrasah system. Modern education system prepares its students on the bases of western education pattern while Maddris develop their students in the light of their own respective schools of thought. Thus, the two educational systems are producing two different categories of graduates, leading to imbalance and intodlerance in the society. To bridge this gap between the two systems and to make the education system harmonious, the government has passed “Pakistan Madrasa ‘h Education Board Ordinance ". Three model Maddris have been set up as a pilot project in Karachi and Sakkar for boys and in Islamabadfor girls. It was supposed to be extended in other cities as well but due to the reservations of Ulamd ' and their bitter opposition, the process did not get due attention among the public. In this paper, the authors will try to bring out the Ulamd’s reservations on "Pakistan Madrasah Education Board” in order to bringforth the policy suggestionsfor the betterment of the program.

Robust Osberver Synthesis for Lipschitz and One-Sided Lipschitz Nonlinear Systems

Practically, system dynamics are nonlinear, requiring the estimation of unknown states, which encourages the observer schemes to be implanted in control structures. This dissertation presents estimation andltering of the Lipschitz and one-sided Lipschitz nonlinear systems and provides robustness against L2 normbounded disturbances and parameter uncertainties for state estimation. The developed approaches overcome the practical consequences of time-delays, perturbations and disturbances. Robust state estimation for Lipschitz and one-sided Lipschitz nonlinear systems is established by the adoption of Luenberger-like observer scheme, which is extended to the generalizedltering scheme to exhibit diverging manifolds, namely, the conventional static-gainlter and dynamiclter as speci c scenarios. Further, the presented estimation schemes unfolded the application based designs, including observer-based control of the nonlinear systems. Observer-based controller application is a duple process: It requires the estimation of unknown states atrst step, while in second stage, a controller is designed using these estimated states. A decoupling condition, necessary and su cient, for the presented approach, is explored to obtain controller and observer gains. Moreover, the controller scheme is further extended to overcome time-varying parametric uncertainties and norm-bounded disturbances. Convex optimization is adopted to solve the nonlinear constraints by combining nested bilinear-term-solver approach with a nonlinear optimization-based cone complimentary linearization. Comprehending the contributions of this dissertation, robust estimation based approaches for Lipschitz and one-sided Lipschitz systems are explored under output delays. Delay-range-dependent stability criterion is adopted to establish the stability, which foregrounds less conservative schemes. Robust generalizedltering for delayed nonlinear systems extends the concept of estimation tolter the noises and perturbations. Furthermore, robust estimation scheme for the nonlinear systems against parametric uncertainties is provided under measurement delay. Robust observer-based controller schemes as applications of the proposed estimation methods are studied. Numerical simulation results of practical systems are provided.