ڈیجیٹل بچے
محمد علی صدیقی
"انٹرنیٹ اور موبائیل نے نوجوان نسل کو کہاں پہنچا دیا ہے سمجھ میں نہیں آتا۔ آنے والا کل نہ جانے کیسا ہو۔!!۔" مینیجنگ کمیٹی کے صدر نے فکرمند لہجے میں کہا۔
"اتنی مایوسی ٹھیک نہی" میں نے کہا۔
میں کچھ اور بھی کہنے والا تھا کہ ایک ٹیچر درجہ چہارم کی ایک بچی کو لے کر آفس میں داخل ہوئیں اور بولیں
"سر یہ آپ سے کچھ کہنا چاہتی ہے۔"
"ہاں۔ کہو" میں نے ان کی طرف متوجہ ہوتے ہوئے کہا۔
"سر۔۔۔ کلاس میں ایک لڑکا مجھے بھابھی بلاتا ہے۔"
وہ اپنی مسکراہٹ چھپانے کی ناکام کوشش کر رہی تھی۔ مجھے کچھ عجیب سا لگا۔ میں نے اس بچے کو بلا کر وارننگ دی اور ٹیچر سے کہا
"آپ لوگ یہ شکایتیں خود ہی سن لیا کریں۔ آفس میں نہ لایا کریں۔"
"ہم تو سنتے ہی رہتے ہیں سر۔ میں نے سوچا کہ آج آپ بھی سن لیں" ٹیچر نے تھکے ہوئے لہجے میں کہا، " کل کے۔جی کا ایک بچہ اپنے ساتھ بیٹھی بچی سے پوچھ رہا تھا کہ کیا وہ اس سے پیار کرتی ہے۔ بچی کی شکایت پر میں نے ان دونوں کو الگ الگ بٹھا دیا لیکن کچھ ہی دیر بعد دونوں پھر ایک ساتھ بیٹھے باتیں کرتے نظر آئے۔"
میں نے ٹیچر کو جانے کا اشارہ کیا اور صدر کی طرف دیکھا۔ ان کے چہرے پر ایک معنی خیز مسکراہٹ کھیل رہی تھی۔
Sources of Quranic Narrates of Syda Mariam (AS): A Critical Analysis of Orientalistic Approach Origin of the Qur’ᾱnic narrates towards Mariam Virgin (AS) has broadly been under debate in orientalist studies. Orientalist, in general, have had the opinion that Qur’ᾱnic stories of virgin Mariam were not the divine revelation; these are plagiarized and utilized from Christian apocryphal sources and literature like Arabic Gospel of infancy and Protoevangelium of James. This research paper’s questions were that according to Orientalist: is it true that the sources of Qur’ᾱnic Stories of Mariam (AS) are plagiarized from apocryphal Christian literature and Quran has done mistake about name of Mariam (AS)'s father and brother. This research is historical and textual. In conclusion, if anyone who has sincerely studied dating apocryphal literature and its dating should be able to see that his sincerity negates taking data for making Qur'ᾱnic narrates towards virgin Mariam (AS) from Christian apocryphal impacts upon Qur'ᾱnic narrate and also this paper shows that Christian developed their apocryphal literature after revelation of Quran.
Pioglitazone is an oral anti-diabetic agent which belongs to a class “thiazolidinediones”. It is used in the treatment of type 2 diabetes mellitus. It acts primarily by increasing peripheral sensitivity to insulin through binding to peroxisome proliferators activated receptor gamma. In recent years, due to variation in pharmacokinetic parameters under different environmental conditions, drug pharmacokinetics has received increasing attention. Therefore, the present study was designed to evaluate the biokinetics, renal clearance and effect on glycation level of pioglitazone in human beings under indigenous conditions. After through clinical examination healthy male volunteers (n = 24), female volunteers (n = 12) and diabetic patients (n = 8) were selected for the study. Each volunteer was given a therapeutic dose of 30 mg pioglitazone tablet orally. Patients were given a dose of 30 mg pioglitazone daily up to 12 weeks. In healthy volunteers scheduled plasma and urine samples were collected at different time intervals. Concentration of pioglitazone in plasma and urine samples was determined by validated high performance liquid chromatographic method. For the estimation of renal clearance of pioglitazone, the endogenous creatinine level was measured in plasma and urine samples spectrophotometrically using kit method based on Jaffe reaction. In plasma samples obtained from healthy volunteers and patients, amount of glucose was estimated by kit method, proteins by Biuret method and glycation level was measured by Thiobarbituric acid (TBA) method, spectrophotometerically. Both differences and similarities are present in the values of different calculated parameters and the values reported in the literature. After comparison minor sex differences were also found to be present in the values of different calculated parameters but statistically these differences were found to be non-significant. A single dose of pioglitazone (30 mg) has no effect on glucose concentration and glycation level in healthy male volunteers. Long term treatment of pioglitazone in diabetic patients, significantly decreased the glucose concentration and glycation level. This indicates that pioglitazone acts as an inhibitor of glycation.