علی اکبر ناطق نے بہت ہی منظم انداز میں کہانی کے پلاٹ کو ترتیب دیا ہے۔مسلمانوں ہندوؤ ں اور انگریزوں کی نفسیاتی کشمکش، کیفیات اس طرح جامع انداز میں منظر عام پر لے کر آئے ہیں گویا محسوس ہوتا ہے کہ ایک ہی وقت میں اس نیان تمام زندگیوں کو جیا ہے اور محسوس کرنے کے بعد اسے ناول کا رنگ دیا ہے۔سکھ ، انگریز ، مسلمان اورجاگیرداروں کی چپقلش کو اس نے وہ عملی جامہ پہنایاہے کہ گرفت بھی قائم رہتی ہے اور اس ہنر مندی نے پلاٹ کو منظم اور موبپط بھی کیا ہے۔
Background: Controversy occurs in the relationship between serum ferritin levels, insulin resistance and risk of developing anemia in adolescents with family history of diabetes. Aims & Objectives: This study was designed to find out the association between serum ferritin levels with risk of developing anemia in non-diabetic adolescents with family history of type 2 diabetes mellitus (T2DM). Materials & Methods: A descriptive cross-sectional was conducted in a local medical institute of Lahore. Study included 50 non-diabetic, non-obese male / female adolescent with family history of type 2 diabetes mellitus and 50 healthy male/female non-obese adolescents without family history of T2DM considered as controls. Level of serum ferritin and serum insulin was estimated by Enzyme Linked Immunosorbent Assay. Blood glucose was estimated by auto-analyzer. Insulin resistance was calculated by HOMA-IR index and beta cell function was assessed by HOMA- beta index. Results: Levels of fasting blood sugar, insulin resistance were found to be increased with decreased level of serum ferritin and decrease beta cell function in both male as well as female cases as compared to controls. Negative correlation was found between serum ferritin and insulin resistance while a positive correlation was found between serum ferritin and beta cell function. Conclusions: Low level of serum ferritin is associated with reduced beta cell function and increased insulin resistance. This may increase the risk of developing iron deficiency anemia that can affect both immune system as well as increase susceptibility to infections.
Genetic modification of the rooting system may lead to more drought tolerant upland cotton. A number of different root and physiological traits have been suggested as important mechanism of drought tolerance of cotton. This study was conducted to identify and map quantitative trait loci (QTLs) conferring root architecture in an interspecific cross Gossypium hirsutum x Gossypium barbadense population. An F 2 population was developed which differed greatly in root characteristics. A genetic map covering 3190.50 cM, with 219 marker loci and 26 linkage groups, was constructed by using this F 2 population. The Two F 2 populations were grown in tube and pots experiments. Tap root traits (length, weight, and lateral root numbers) were evaluated. QTL analysis via composite interval mapping detected 17 QTLs, for three root traits including 3 QTLs for fresh root weight, 6 QTLs for lateral root numbers, and 2 QTLs for tap root length in tube experiment, while in pot experiment, 3 QTLs for fresh root weight and 3 QTLs for lateral root numbers were identified. Individually the QTLs accounted for 11-28% of phenotypic variation. Common QTLs were indentified for fresh root weight and lateral root numbers on chr. 18 & chr. 25 respectively, in both pot and tube experiments. The QTLs for root traits, firstly detected in Gossypium, may provide a basis for marker-assisted selection to improve productivity in root-crop breeding.