سوشل میڈیا کا استعمال اخلاقیات اور شریعت کے نکتہ نظر سے: ایک تفصیلی جائزہ

Throughout the history humanity has witnessed many ups and downs. There might have been many eras of moral lawlessness in which humanity might have suffered from lack of moral character, civilization, lack of social norms and values and many such things. But in the present era social media has emerged as a very sharp sword which has destroyed social values, norms and morality. It has proven destructive to a unprecedented level. Sometimes people share news about a person without conformation and on other times people destroy human shapes and give them resemblance with animal shapes and then share them on social media by way of comparison between human and animals. Insulting political opponents, playing with honor and dignity of others, humiliating others have become a game to play for people on social media. Many users of the social media think that there is no respect for others at all so they don’t hesitate from humiliating people. For them the only act worth doing is to protect the so called respect of the leader they follow and love. They are ready to cross any limit for this.  While doing all this they forget anything and everything about civility, morality, and social values etc. Someone has quite rightly said that good character is proof of good blood. While using social media one is in fact representing one’s family and blood. According to statistics 58% of the whole population of our country consists of young people the majority of which is so much attached and engrossed with the use of social media that they are oblivious of what is going around them. The spell of social media has bound people in the galleries of hospitals, pathways, passengers, and in educational institutes. So much so that even in homes, social media has preoccupied people to an extent that they damn care for the people living in the same home with them. There is value for a friend on social media but there is no value for a person sitting very next to them. A young man is busy and engaged with a so called sister on social media but his real sister is seen tantalized for his care and affection. In the university students miss out lectures of teacher but want to learn things from google and social media. This is the dilemma of the current age. The use of social media has taken people far away from the people sitting and living very close to them. Now the young generation has options i.e. Positive or negative use of social media. Your face book account, your profile is reflective of your personality. Any visitor, while visiting your profile and account will have your whole personality open up to him. Difference of opinion is permitted and appreciable thing but it should be done within limits. The current research paper is an attempt to cover up all these things and to see the Islamic teachings about the use of social media. How to open an account on social media, how to share pictures on it either self or that of others, sending friend requests and accepting them? These and other related issues will be discussed in the present paper in the light of Islam.

Assessment of Anti-Proliferative and Anti-Inflammatory Potential of Thymoqunione Tq and Thymohydroquinone Thq Coupled With Poly Lactide-Co-Glycolide Nanoparticles

Current study was designed to extract phytochemical compounds, thymoquinone (TQ) and thymohydroquinone (THQ) from indigenous herbs i.e., Nigella sativa (seeds) and Thymus vulgaris (aerial parts). Extracted compounds were further subjected to evaluate their anti-proliferative and anti-inflammatory activities and loaded in novel biodegradable drug carrier system including pectin and poly lactide-co-glycolide (PLGA) to achieve a controlled drug release system. Drug carrier system was synthesized by extracting pectin from waste peels of citrus fruits (lemon, orange and grape fruit). To enhance the stability, FDA approved PLGA drug carrier was physically cross-linked with pectin hydrogel. This may potentially introduce an opportunity to utilize organic waste in pharmacology.Results showed that soxhlet extraction at ratio of n-hexane: methanol (1:4) has been the appropriate combination to extract maximum yield of TQ from N. sativa (56.13%) and T. vulgaris (22%). THQ extraction was not achievable due to its very less stability. HPLC quantification of essentials oil of N. sativa showed higher amount of TQ i.e., 368.55±0.12 mg/kg (Mean±SEM) and T. vulgaris had 197.58±0.7 mg/kg. The pectin was successfully extracted in maximum yield from waste peels of lemon as compared to other two samples i.e., 35.3±0.66 g (Mean±SEM). Characterization of pectin extracted from each samples showed orange pectin potentially more suitable for hydrogel formation. SEM analysis confirmed the nanoparticles of TQ efficaciously produced loaded in PLGA-PEG at average size of 280 nm. TQ has been proved to be potent anti-proliferative and anti-inflammatory agent by in-vivo antioxidant assays (DPPH and FRAP assay), MTT assay against HeLa cancer cell line and SRB assay against HCT116 colon cancer cell line. Inhibition concentration (IC50) of TQ against HeLa and HCT116 cancer cell lines showed less significant difference (p > 0.05) to the IC50 of control commercial anti-cancer drug (cisplatin). TQ and its nanoparticles loaded in pectin hydrogel showed delayed release of TQ thus enabling the controlled drug release from 24 to 72 hours. TQ thus obtained can be utilized against early treatments of variety of cancers as can be observed from IC50 obtained against HeLa and HCT116 cancer cell lines. Findings of the current study indicate the potential of local resources in effectiveness against cancer. Therefore, increased incidences of cancer can be reduced among impoverished areas.