سید غلام محی الدین
دوسرا حادثہ جناب سید غلام محی الدین کی وفات کا ہے، جو بڑے خاموش، متین، متواضع اور ذی علم شخص تھے۔ مولانا آزاد میموریل اکیڈمی لکھنؤ کے روح رواں اور اس کے انگریزی جرنل کے ایڈیٹر تھے، وہ مجلس تحقیقات و نشریات اسلام لکھنؤ کے بھی نہایت سرگرم رکن اور انگریزی کے اچھے اہل قلم تھے، مولانا سیدابوالحسن علی ندوی مدظلہ سے بڑا مخلصانہ تعلق رکھتے تھے، ان کے دینی و دعوتی کاموں میں ان کے معادن بھی تھے، ان کی متعدد کتابوں اور مضامین کا انگریزی ترجمہ کیا، مولانا ان کی خاموش خدمت اور علمی صلاحیت کے معترف تھے، عرصہ سے تنفس کا مرض لاحق ہوگیا تھا۔ بالاخر ۹؍ نومبر کو وقت موعود آگیا، اﷲ تعالیٰ ان کے درجات بلند فرمائے، آمین۔ (ضیاء الدین اصلاحی، دسمبر ۱۹۹۶ء)
The question of moral rectitude and upbringing of youth in the current social arena is the contemporary discovery attributed to social and family norms that also undergo change due to social and economic reasons. Consequently, deferring levels of piety become more or less acceptable according to an individual’s surroundings and age. The study was done to determine the association between religiosity and behaviors likely to improve the moral, social and psychological habits of young Muslims. The discussion of the article contextualizes the effects of observing practices of Islam on a larger scale. A sample study of this research can be used as evidence to counter the contemporary environment which inevitably generates contradictions for young people. The contradictions result in uncertainty and materialistic atmosphere which does not cater to their spiritual needs and the requirements to develop as the youth of Ummah. Yet, we cannot stop or avoid the negative channels and their effects prevailing on the internet. We can; however, extend the positive spiritual energy in youth that is only possible through careful observance of religious practices comprising regular prayers, fasting, charity and pilgrimage (Hajj). The current apathy of our youth towards the religious injunctions may be attributed to social and family norms that are in some cases relative to the economic conditions and social backup. This will evaluate and assess the way and means of effective inlaying of moral fields where our young people can improve their moral aptitude and rectitude. The impasse of current moral turpitude can be shattered with the bounding relation of human activity and Islamic ritual.
Liver is an essential organ that controls around various physiological functions such as production of bile, plasma proteins, and hormones aids in digestion and detoxification of drugs as well. Drug induced liver injury (DILI) is the principal cause of acute liver failure (ALF) in various countries. There is a broad array of anti-psychotic drugs (APDs) which are used to treat bipolar disorders most commonly schizophrenia and other neuro-psychotic disorders. One of the two famous anti-psychotic agents; aripiprazole and ziprasidone belong to atypical class of anti-psychotics. Although APDs are currently being used all over the world yet these drugs have displayed many side effects. In-vivo estimation of acute liver injury level by APDs therefore bears significance so as to determine the efficacy and identify potential health hazards. Current study will determine the liver injury induction potential of APDs in animal model.To induce acute liver injury, acetaminophen (APAP) was used. The foremost drug responsible for DILI is APAP which induces oxidative stress and dysfunction of mitochondria. Collection of blood samples was done in aseptic conditions, and collected serum was subjected to biochemical estimations. Serum ALP and ALT levels has been assessed to determine the effect of APDs on liver functioning efficiency. Estimation of serum ferritin has provided iron storage estimation. Moreover, the study had also evaluated the renal efficiency changes induced by APDs via estimation of urea and creatinine levels. HDL, LDL, TG and cholesterol levels were also estimated to identify the effect of these drugs on lipid profile. Thus, the study will provide a rationale for the utilization of APDs and their effects on a body system, in comparison to APAP induced acute liver injury.