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Combinatorial Solution Phase Synthesis of Molecular Libraries of Chalcones As Potential Antibacterial and Cytotoxic Agents

Thesis Info

Author

Samina Nazir

Department

Deptt. of Chemistry, QAU.

Program

Mphil

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2005

Thesis Completion Status

Completed

Page

ii,81

Subject

Chemistry

Language

English

Other

Call No: DISS/M.Phil CHE/622

Added

2021-02-17 19:49:13

Modified

2023-02-19 12:33:56

ARI ID

1676718456646

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مولوی مظہر الحق

مولوی مظہرالحق صاحب پٹنہ
جس طرح ہمارا پرانا سال ایک بڑے قومی حادثہ یعنی پرانی تعلیم کے ایک بہترین نمونہ (مولانا حبیب الرحمان عثمانی دیوبندی) کے دائمی فقدان پر ختم ہوا، اسی طرح ہمارے نئے سال کا آغاز بھی ایک بڑے قومی حادثہ یعنی نئی تعلیم کے ایک بہترین نمونہ (مولوی مظہرالحق صاحب بیرسٹر پٹنہ) کی دائمی جدائی سے ہوا، مولوی مظہرالحق صاحب مرحوم کی قومی و سیاسی حیثیت تو الگ ہے، ان کی اخلاقی اور علمی حیثیت بھی کچھ کم قابل ذکر نہیں ہے، وہ فارسی سے واقف، عربی سے آشنا، انگریزی کے ادیب و خطیب اور فلسفہ کے نہایت دقیقہ رس طالبعلم تھے، ان کے علمی کارناموں کا آغاز طوفان نوح کی بحث سے ہوا، الپنچ پٹنہ اور وقت گورکھپور ان کے ابتدائی علمی مباحث کے جولان گاہ تھے، ان کی سب سے آخری علمی تحریر غالباً وہ ہے جو ابھی ابھی پونہ سے شائع ہونے والی انگریزی کی کتاب تصوف و روحانیت پر مقدمہ ہے، وہ نسباً فاروقی تھے، اس لئے ان کی اخلاقی قوت و جرأت کیا سلطنت اور کیا قوم دونوں کے مقابلہ میں برابر تھی، وہ جس کو حق سمجھتے تھے اس کے اظہار میں نہ ان کو سلطنت کی پروا ہوتی تھی اور نہ قوم کی، ان کا یوروپین طرز معاشرت کو الوداع کہہ کر وفعتہ مشرقی اور غالی مشرقی بن جانا ان کی بے مثال اخلاقی جرأت کا نمونہ ہے، مرحوم کی آخری عمر روح و روحانیت کی تحقیق میں صرف ہوئی، خدا ان کی روح کو اپنی مغفرت کی لازوال دولت سے مالا مال کرے، اب وہ وہاں پہنچ چکی ہے، جہاں کے کشف زار کے لئے وہ بے قرار تھی۔ (سید سلیمان ندوی، جنوری ۱۹۳۰ء)

 

مولانا سید زوار حسین شاہ کے تراجم: ایک تعارفی جائزہ

Hazrat Maulana Syed Zawwar Hussain Shah is the knowledgeable and spiritual personality of the fourteenth century Hijra. There are diverse aspects of his qualities and perfections. A matchless diversity can easily be found in his services related to his scholarly work and reformation of Muslim Ummah. Not only a Translator, Biographer or Poet but he, at the same time, was also an expert of Islamic Jurisprudence and held the position of a Sheikh of Islamic Sufi order of Naqshbandi Mujaddiah. Shah Sahib authored and compiled 13 books. The study of translated works ( Mabda wa Ma’ad, Muarif-e-Ludniya, Maktoobat-e-Masoomia, Maktoobat Imam Rabbani) of Shah Sahib's and discussion on its importance is the prime focus of this article.

Process Modification for Improvement in Conventional Reactive Printing of Cotton Fabric

Current study was based on the imperative constituent’s replacement of the reactive printing paste for cotton printing. They are sodium alginate, sodium bicarbonate and urea. Although sodium alginate is a natural thickener and environment friendly, but its availability and cost are the major concern which motivated the researcher to replace it with some better constituent. Other main part of the printing paste recipe is urea. Urea is nitrogen containing compound and it causes water stream pollution. It supports the reactive dyes molecule in solubility and moisture management to the fabric. Moisture helps the dye shade to remain sharp and shine during steaming process. The third and final replacement was sodium bicarbonate. Alkali is prerequisite in printing as reactive dyes form covalent bond to cellulosic cotton in alkaline condition. However, alkali hydrolyzes the dye molecules as well. Also, it has detrimental effects towards environment. Sodium alginate was replaced with synthetic acrylic thickener and tamarind kernel powder after its carboxy methyl substitution. Its degree of substitution was dignified by using both dry and wet methods. 0.654 was the DS value with dry method and 0.661 was the DS value with wet method. Urea was replaced with nitrogen free polymer i.e. polyethylene glycol 400 which increased dye solubility. Sodium bicarbonate was replaced with tri chloro acetic acid. Tri chloro acetic acid dissociated at high temperature around 100℃ and became alkaline (as required for fixation) during steaming process of the printed fabric. Five Mono chloro triazine and one vinyl sulphone reactive dye was selected for reactive printing. One conventional recipe was prepared with sodium alginate (2%), sodium bicarbonate (2.5%) and urea (15%) and six modified recipes were prepared against standard recipe 1. Recipe 2 included acrylic synthetic thickener (3%) and the rest of the chemicals were same as recipe 1. Recipe 3 and 4 have mixed ratio of SA and AST. Recipe 5 was prepared by using TCAA (4%) and CMTKP (6%). Recipe 6 by adding PEG-400 (2%) in recipe 5. In recipe 7, PEG-400 (1%) reduction in recipe 6. All 7 seven recipes were used in 6 reactive dyes at two dose levels (2% and 4%). There were total 84 trials of reactive printing and each trial was accessed with 9 tests. Sum K/S and shade strength, penetration of the dyes into the fabric, staining on the white ground of the fabric, washing fastness (change in shade and staining), rubbing fastness (dry and wet), light fastness, perspiration fastness (acidic and basic), sharpness of the edges, fabric hardness and cost saving. After running 6 colours at different dose levels, it was confirmed that recipe 6 is best in all aspects. However, based on cost and results, recipe 7 had better outcomes than recipe 1.